Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Additionally we are shipping SNCA Proteins (68) and SNCA Kits (67) and many more products for this protein.
Showing 10 out of 650 products:
Human Monoclonal SNCA Primary Antibody for EIA, IHC (fro) - ABIN264097
Trojanowski, Lee: \' of proteins. A comprehensive hypothetical mechanism underlying Alzheimer's disease and other neurodegenerative disorders. in Annals of the New York Academy of Sciences 2001
Show all 9 references for ABIN264097
Human Polyclonal SNCA Primary Antibody for EIA, IHC (p) - ABIN358988
Kumru, Santamaria, Tolosa, Valldeoriola, Muñoz, Marti, Iranzo: Rapid eye movement sleep behavior disorder in parkinsonism with parkin mutations. in Annals of neurology 2004
Show all 5 references for ABIN358988
Human Polyclonal SNCA Primary Antibody for EIA, WB - ABIN358993
Pigullo, De Luca, Barone, Marchese, Bellone, Colosimo, Scaglione, Martinelli, Di Maria, Pizzuti, Abbruzzese, Dallapiccola, Ajmar, Mandich: Mutational analysis of parkin gene by denaturing high-performance liquid chromatography (DHPLC) in essential tremor. in Parkinsonism & related disorders 2004
Show all 5 references for ABIN358993
Human Monoclonal SNCA Primary Antibody for EIA, IHC (fro) - ABIN264470
McLean, Kawamata, Ribich, Hyman: Membrane association and protein conformation of alpha-synuclein in intact neurons. Effect of Parkinson's disease-linked mutations. in The Journal of biological chemistry 2000
Show all 3 references for ABIN264470
Human Monoclonal SNCA Primary Antibody for ICC, FACS - ABIN439712
Huang, Xu, Wu, Zhou: Determining nuclear localization of alpha-synuclein in mouse brains. in Neuroscience 2011
Show all 2 references for ABIN439712
Human Polyclonal SNCA Primary Antibody for WB - ABIN390368
West, Kapatos, OFarrell, Gonzalez-de-Chavez, Chiu, Farrer, Maidment: N-myc regulates parkin expression. in The Journal of biological chemistry 2004
Show all 2 references for ABIN390368
Human Polyclonal SNCA Primary Antibody for IHC (p), WB - ABIN390364
Wang, Denison, Lai, Philips, Montoya, Kock, Schüle, Klein, Shridhar, Roberts, Smith: Parkin gene alterations in hepatocellular carcinoma. in Genes, chromosomes & cancer 2004
Show all 2 references for ABIN390364
Human Polyclonal SNCA Primary Antibody for ELISA, WB - ABIN1533020
Campion, Martin, Heilig, Charbonnier, Moreau, Flaman, Petit, Hannequin, Brice, Frebourg: The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease. in Genomics 1995
Cow (Bovine) Polyclonal SNCA Primary Antibody for WB - ABIN2775366
Wu, Kim, Fela, Baum: Characterization of conformational and dynamic properties of natively unfolded human and mouse alpha-synuclein ensembles by NMR: implication for aggregation. in Journal of molecular biology 2008
study examined the spatial and temporal expression patterns of three synuclein genes (snca, sncbb, sncg (show SNCG Antibodies)) during embryogenesis
Data suggest the produced mouse lines represent a set of useful tools for studies of alpha-synuclein normal function and the role of this protein in disease pathogenesis.
that loss of glucocerebrosidase (show GBA Antibodies) function may contribute to SNCA accumulation through inhibition of autophagy via PPP2A inactivation
provides evidence for a novel interaction of alpha-synuclein and SOD1 (show SOD1 Antibodies) that might be relevant for neurodegenerative diseases
It found that chromosome 1 harbors an expression quantitative trait locus that modulates Sncg (show SNCG Antibodies) expression in the mouse retina, and identified the prefoldin-2 (PFDN2 (show PFDN2 Antibodies)) gene as the candidate upstream modulator of Sncg (show SNCG Antibodies) expression.
The response of CPLX1 (show CPLX1 Antibodies) and Foxp1 (show FOXP1 Antibodies) levels to SNCA deficiency supports the notion that these factors are regulated by altered physiological function of alpha-synuclein.
The pattern of expression and distribution of alpha-synuclein during the development of ciliary body and iris of mice, chick and fish data concluded that alpha-synuclein has important cellular function during eye development of studied animals.
Longitudinal Metabolomics Profiling of Parkinson's Disease-Related alpha-Synuclein A53T Transgenic Mice.
This would suggest that as complex I-deficient cells have already adapted to their mitochondrial defect, the subsequent toxic effects of alpha-synuclein are reduced.
The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice and has an important role.
These findings support a reciprocal modulatory interaction of alpha-syn and synapsin III (show SYN3 Antibodies) in the regulation of dopamine neuron synaptic function.
Samples were taken from six sites and immunostained for phosphorylated alpha-synuclein
This study deminstrated that alpha-Synuclein methylation levels depended on disease status, sex, age, and the genotype of rs3756063.
HMGB1 (show HMGB1 Antibodies) or Beclin1 (show BECN1 Antibodies) upregulate alpha-synuclein degradation, ameliorating alpha-synuclein-mediated autophagy reduction in PC12 cells.
his study showed that decreased Levels of monomeric Alpha-Synuclein correlate with Duration of Dementia.
Chemical cross-linking in combination with solution-state NMR and multiangle static light scattering (MALS (show NCR3 Antibodies)) of alpha-Syn particles reveal a high-order protein-lipid entity composed of approximately 8-10 alpha-Syn molecules.
Results imply that accumulating alpha-synuclein severely affects hippocampal neurogenesis paralleled by impaired 5-HT (show DDC Antibodies) neurotransmission prior to the onset of aggregation pathology and overt motor deficits in a transgenic rat Parkinson's disease model
utility of alpha-synuclein as biofluid marker in neurodegenerative diseases
single-molecule Forster Resonance Energy Transfer to visualize directly the protein self-assembly process by wild-type alpha-synuclein and A53T, A30P and E46K mutants and to compare the structural properties of the ensemble of oligomers generated.
An alpha-synuclein mutant inhibited two forms of endocytosis, slow and rapid, in central nerve terminals.
analysis of membrane curvature sensing by amphipathic helices using alpha-synuclein and annexin B12 (show TNFAIP1 Antibodies) [ANXB12]
Immunocytochemistry shows alpha synuclein localized to the Golgi apparatus and vesicles of bovine adrenal medullary chromaffin cells, consistent with its putative role in vesicular function within synapses.
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
, alpha SYN
, non-A beta component of AD amyloid
, non-A4 component of amyloid
, non A-beta component of AD amyloid
, synuclein alpha-140
, alpha synuclein