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anti-Synuclein, alpha (SNCA) Antibodies

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Additionally we are shipping SNCA Proteins (71) and SNCA Kits (56) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SNCA 20617 O55042
SNCA 6622 P37840
SNCA 29219 P37377
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Top anti-SNCA Antibodies at antibodies-online.com

Showing 10 out of 656 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Western blot analysis of anti-Alpha-synuclein Pab in mouse brain tissue lysate. Alpha-synuclein (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, IHC (fro), WB 0.1 mg Log in to see 6 to 8 Days
$687.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SNCA Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-Alpha-synuclein Pab (ABIN390368) in mouse brain tissue lysate. Alpha-synuclein (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of anti-Alpha-synuclein Pab in mouse brain tissue lysate. Alpha-synuclein (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from mouse brain, using Synuclein-alpha (Phospho-Tyr136) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-Alpha-synuclein Pab (ABIN390364) in mouse brain tissue lysate. Alpha-synuclein (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ICC, FACS, IHC (fro), IF, IHC (p), IHC, WB Flow Cytometry: Synuclein-alpha [Nitrate Tyr125, Nitrate Tyr133] Antibody (24.8) [NBP1-26380] - Intracellular flow cytometric staining of 1 x 10^6 CHO (A) and HeLa (B) cells using Synuclein-alpha [Nitrate Tyr125, Nitrate Tyr133] antibody (dark blue). Isotype control shown in orange. An antibody concentration of 1 ug/1x10^6 cells was used. 0.1 mL Log in to see 5 to 7 Days
$408.19
Details
Human Mouse Un-conjugated ELISA, WB Western Blot: Synuclein-alpha Antibody (5C2) [NBP1-04321] - The recombinant human synuclein family (alpha-, beta- and gamma-) and alpha-synuclein domains (1-60, 1-95, 61-140 and 96-140) proteins were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-alpha-Synuclein (61-95 aa) antibody (1:1,000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 0.1 mL Log in to see 5 to 7 Days
$447.56
Details
Human Mouse Un-conjugated EIA, IHC (fro), IHC (p), WB   0.2 mL Log in to see 6 to 8 Days
$1,314.50
Details

SNCA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SNCA Antibodies

  1. Human Monoclonal SNCA Primary Antibody for EIA, IHC (fro) - ABIN264097 : Trojanowski, Lee: \' of proteins. A comprehensive hypothetical mechanism underlying Alzheimer's disease and other neurodegenerative disorders. in Annals of the New York Academy of Sciences 2001 (PubMed)
    Show all 9 references for ABIN264097

  2. Human Polyclonal SNCA Primary Antibody for EIA, IHC (p) - ABIN358988 : Kumru, Santamaria, Tolosa, Valldeoriola, Muñoz, Marti, Iranzo: Rapid eye movement sleep behavior disorder in parkinsonism with parkin mutations. in Annals of neurology 2004 (PubMed)
    Show all 5 references for ABIN358988

  3. Human Polyclonal SNCA Primary Antibody for EIA, WB - ABIN358993 : Pigullo, De Luca, Barone, Marchese, Bellone, Colosimo, Scaglione, Martinelli, Di Maria, Pizzuti, Abbruzzese, Dallapiccola, Ajmar, Mandich: Mutational analysis of parkin gene by denaturing high-performance liquid chromatography (DHPLC) in essential tremor. in Parkinsonism & related disorders 2004 (PubMed)
    Show all 5 references for ABIN358993

  4. Human Monoclonal SNCA Primary Antibody for EIA, IHC (fro) - ABIN264470 : McLean, Kawamata, Ribich, Hyman: Membrane association and protein conformation of alpha-synuclein in intact neurons. Effect of Parkinson's disease-linked mutations. in The Journal of biological chemistry 2000 (PubMed)
    Show all 3 references for ABIN264470

  5. Human Monoclonal SNCA Primary Antibody for ICC, FACS - ABIN439712 : Huang, Xu, Wu, Zhou: Determining nuclear localization of alpha-synuclein in mouse brains. in Neuroscience 2011 (PubMed)
    Show all 2 references for ABIN439712

  6. Human Polyclonal SNCA Primary Antibody for WB - ABIN390368 : West, Kapatos, OFarrell, Gonzalez-de-Chavez, Chiu, Farrer, Maidment: N-myc regulates parkin expression. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN390368

  7. Human Polyclonal SNCA Primary Antibody for IHC (p), WB - ABIN390364 : Wang, Denison, Lai, Philips, Montoya, Kock, Schüle, Klein, Shridhar, Roberts, Smith: Parkin gene alterations in hepatocellular carcinoma. in Genes, chromosomes & cancer 2004 (PubMed)
    Show all 2 references for ABIN390364

  8. Human Polyclonal SNCA Primary Antibody for ELISA, WB - ABIN1533020 : Campion, Martin, Heilig, Charbonnier, Moreau, Flaman, Petit, Hannequin, Brice, Frebourg: The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease. in Genomics 1995 (PubMed)

  9. Cow (Bovine) Polyclonal SNCA Primary Antibody for WB - ABIN2775366 : Wu, Kim, Fela, Baum: Characterization of conformational and dynamic properties of natively unfolded human and mouse alpha-synuclein ensembles by NMR: implication for aggregation. in Journal of molecular biology 2008 (PubMed)

More Antibodies against SNCA Interaction Partners

Xenopus laevis Synuclein, alpha (SNCA) interaction partners

  1. study examined the spatial and temporal expression patterns of three synuclein genes (snca, sncbb, sncg (show SNCG Antibodies)) during embryogenesis

Mouse (Murine) Synuclein, alpha (SNCA) interaction partners

  1. alpha-synuclein may have a varying modulating effect on the growth dynamics and the fate of populations of DA neurons.

  2. In the olfactory bulb, globus pallidus and substantia nigra pars (show EPRS Antibodies) compacta, alpha-synuclein was expressed, but not in the cerebral cortex, subthalamic nucleus or thalamus.

  3. identified alpha-synuclein as a new transcriptional target of p53 (show TP53 Antibodies)

  4. High SNCA expression is associated with epilepsy.

  5. Data suggest the produced mouse lines represent a set of useful tools for studies of alpha-synuclein normal function and the role of this protein in disease pathogenesis.

  6. that loss of glucocerebrosidase (show GBA Antibodies) function may contribute to SNCA accumulation through inhibition of autophagy via PPP2A inactivation

  7. provides evidence for a novel interaction of alpha-synuclein and SOD1 (show SOD1 Antibodies) that might be relevant for neurodegenerative diseases

  8. It found that chromosome 1 harbors an expression quantitative trait locus that modulates Sncg (show SNCG Antibodies) expression in the mouse retina, and identified the prefoldin-2 (PFDN2 (show PFDN2 Antibodies)) gene as the candidate upstream modulator of Sncg (show SNCG Antibodies) expression.

  9. The response of CPLX1 (show CPLX1 Antibodies) and Foxp1 (show FOXP1 Antibodies) levels to SNCA deficiency supports the notion that these factors are regulated by altered physiological function of alpha-synuclein.

  10. The pattern of expression and distribution of alpha-synuclein during the development of ciliary body and iris of mice, chick and fish data concluded that alpha-synuclein has important cellular function during eye development of studied animals.

Human Synuclein, alpha (SNCA) interaction partners

  1. This mathematical approach confirmed the clustering of premotor markers in preclinical stage of Parkinson's disease. This is the first report showing that alpha-synuclein in the colon and other premotor markers are related to each other in neurologically normal subjects.

  2. Hypomethylation of CpG islands located in intron 1 of the SNCA in leukocytes of dementia with Lewy bodies.

  3. Findings indicate that alpha-synuclein pathology in the peripheral nerves is axonal-predominant in Lewy body disease, whereas it is restricted to glial cells in multiple system atrophy.

  4. The subgroup of PD showed higher levels of CSF (show CSF2 Antibodies) alpha-synuclein (38.3 +/- 17.8 ng/ml) than the rest (25.3 +/- 11.3 ng/ml, P = 0.012). These results suggest that PD (and MSA (show TPO Antibodies)) includes two subgroups, which show different metabolism of CSF (show CSF2 Antibodies) transferrin (show Tf Antibodies) and alpha-synuclein.

  5. Programmed cell death protein 1 (PD1 (show PDCD1 Antibodies)) and programmed death-ligand 1 (PDL1 (show CD274 Antibodies)) status by immunohistochemistry was not associated with outcomes. The use of immune checkpoint blockade in tumors with higher mutational load was associated with improved OS. Our results suggest that the evaluation of tumor genomes may be predictive of immunotherapy benefit

  6. SNCA variant carriers with have more favorable treatment responses to deep brain stimulation.

  7. This study demonstrateed that the rs11931074 in SNCA association with PD risk in Iran population.

  8. extent of phosphorylated alpha-synuclein-immunoreactive astrocytes was correlated with disease durationfa

  9. the 5'-UTR (show UTS2R Antibodies) is an important positive regulator of SNCA synthesis under diverse physiological and pathological conditions.

  10. Intrinsic and membrane-facilitated alpha-synuclein oligomerization characteristic of Parkinson's disease has been revealed in model systems in solution.

Cow (Bovine) Synuclein, alpha (SNCA) interaction partners

  1. analysis of membrane curvature sensing by amphipathic helices using alpha-synuclein and annexin B12 (show TNFAIP1 Antibodies) [ANXB12]

  2. Immunocytochemistry shows alpha synuclein localized to the Golgi apparatus and vesicles of bovine adrenal medullary chromaffin cells, consistent with its putative role in vesicular function within synapses.

SNCA Antigen Profile

Protein Summary

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.

Gene names and symbols associated with anti-Synuclein, alpha (SNCA) Antibodies

  • synuclein, alpha (snca) antibody
  • alpha-synuclein (LOC619283) antibody
  • alpha-synuclein (LOC100359228) antibody
  • synuclein, alpha (Snca) antibody
  • synuclein, alpha (non A4 component of amyloid precursor) (SNCA) antibody
  • synuclein, alpha (non A4 component of amyloid precursor) (Snca) antibody
  • alphaSYN antibody
  • LOC619283 antibody
  • MGC64356 antibody
  • NACP antibody
  • PARK1 antibody
  • PARK4 antibody
  • PD1 antibody
  • snca antibody

Protein level used designations for anti-Synuclein, alpha (SNCA) Antibodies

synuclein, alpha , alpha-synuclein , alpha SYN , non-A beta component of AD amyloid , non-A4 component of amyloid , non A-beta component of AD amyloid , synuclein alpha-140 , alpha synuclein

GENE ID SPECIES
380315 Xenopus laevis
619283 Takifugu rubripes
100359228 Oryctolagus cuniculus
20617 Mus musculus
6622 Homo sapiens
29219 Rattus norvegicus
641350 Sus scrofa
282857 Bos taurus
395393 Gallus gallus
100294604 Ovis aries
Selected quality suppliers for anti-SNCA (SNCA) Antibodies
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