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TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa Proteins (TAF1)

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. Additionally we are shipping TAF1 Antibodies (69) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse TAF1 TAF1 270627  
Rat TAF1 TAF1 317256  
TAF1 6872 P21675
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Top TAF1 Proteins at antibodies-online.com

Showing 3 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag,DYKDDDDK Tag Recombinant TAF1 (1522-1656) activity using AlphaScreen. TAF1 (1522-1656) activity was assessed using an AlphaScreen® assay testing various buffer formulations. This data was generated and kindly provided courtesy of ChemPartner. Recombinant TAF1 (1522-1656) protein gel. TAF1 (1522-1656) protein was run on an SDS-PAGE gel and stained with Coomassie blue. 100 μg Log in to see 1 to 2 Days
$460.83
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details

TAF1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) Interaction Partners

Fruit Fly (Drosophila melanogaster) TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) interaction partners

  1. TAF1 is involved in both establishing an upper limit of transcription during induction and efficiently turning the gene off once the inducer is removed

  2. results suggest stepwise assembly of a testis-specific (show TUBA1B Proteins) TFIID (show TAF8 Proteins) complex (tTFIID) whereby a TAF1 isoform, presumably TAF1-2, is recruited to a core subassembly of tTAFs in spermatocyte nucleoli

  3. TAF1 pre-mRNA elements identified in this study are independently targeted by developmental signaling pathways to result in tissue-specific inclusion of exon 12a and/or 13a.

  4. The existence of a stable coactivator supercomplex consisting of the chromatin-remodeling factor (show ASH1L Proteins) Brahma (show SMARCA2 Proteins) (SWI (show SMARCA1 Proteins)/SNF (show SNRPA Proteins)) and the transcription initiation factor TFIID (show TAF8 Proteins), is shown.

Mouse (Murine) TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) interaction partners

  1. Data show that Taf1 is decreased at the osteogenic initiation stage in the maxilla of Tgfbr2 (show TGFBR2 Proteins) mutant mice.

Human TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) interaction partners

  1. The bromodomains of BRD9, CECR2, and the second bromodomain of TAF1 recognize the longer butyryl mark on histones. In addition, the TAF1 second bromodomain is capable of binding crotonyl marks.

  2. TAF1 variants are associated with dysmorphic features, intellectual disability, and neurological manifestations.

  3. TAF1 winged helix domain has intrinsic DNA-binding activity, which depends on characteristic residues that are commonly used by winged helix fold proteins for interacting with DNA.

  4. the surface of the TAF1-TAF7 (show TAF7 Proteins) complex contains two prominent conserved surface pockets, one of which binds selectively to an inhibitory trimethylated histone H3 (show HIST3H3 Proteins)

  5. This study demonistrated that frequencies of polymorphic genotype and allele of TAF1 gene were not different in patients than in control group and that they were not significant for cerebral venous thrombosis.

  6. As cellular ATP levels recover, TAF1 is able to phosphorylate p53 (show TP53 Proteins) on Thr55, which leads to dissociation of p53 (show TP53 Proteins) from the p21 (show CDKN1A Proteins) promoter.

  7. Lower efficiency of microRNA synthesis directed by TATA box or NF-kappaappaB is a consequence of frequent transcription initiations that lead to RNA polymerase II crowding at pause sites and premature termination.

  8. Although d3-d4 also affect genes potentially related to neurodegenerative processes, their physiologic role as splice variants of TAF1 awaits further exploration

  9. analysis of phosphorylation-dependent regulation of cyclin D1 (show CCND1 Proteins) and cyclin A (show CCNA2 Proteins) gene transcription by TFIID (show TBP Proteins) subunits TAF1 and TAF7 (show TAF7 Proteins)

  10. In the Brazilian population, genetic variations in both uPA (show PRAP1 Proteins) and TAFI (show CPB2 Proteins) were not relevant to endometriosis and/or infertility.

TAF1 Protein Profile

Protein Summary

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. This gene is part of a complex transcriptional unit (TAF1/DYT3), wherein some products share exons with TAF1 as well as additional exons downstream.

Gene names and symbols associated with TAF1

  • TBP-associated factor 1 (Taf1)
  • TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa (TAF1)
  • transcription initiation factor TFIID subunit 1 (AaeL_AAEL006082)
  • transcription initiation factor TFIID subunit 1 (CpipJ_CPIJ003658)
  • transcription initiation factor TFIID subunit 1 (TAF11.1)
  • transcription initiation factor TFIID, subunit TAF1 (HAF1501)
  • transcription initiation factor TFIID, subunit TAF1 (HAF1502)
  • TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf1)
  • TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa (Taf1)
  • 250kDa protein
  • AU015687 protein
  • B430306D02Rik protein
  • BA2R protein
  • BG:DS00004.13 protein
  • Ccg-1 protein
  • CCG1 protein
  • CCGS protein
  • cel protein
  • cell protein
  • CG17603 protein
  • d230 protein
  • Dmel\\CG17603 protein
  • dmTAF1 protein
  • dmTAF[[II]]230 protein
  • dTAF230 protein
  • dTAF250 protein
  • dTAFII250 protein
  • dTAF[[II]]230 protein
  • dTAF[[II]]250 protein
  • DYT3 protein
  • DYT3/TAF1 protein
  • EfW1 protein
  • KAT4 protein
  • l(3)84Ab protein
  • N-TAF1 protein
  • NSCL2 protein
  • OF protein
  • p230 protein
  • p250 protein
  • RGD1562050 protein
  • SR3-5 protein
  • TAF protein
  • TAF(II)250 protein
  • TAF1 protein
  • Taf1p protein
  • TAF2A protein
  • Taf200 protein
  • Taf230 protein
  • Taf250 protein
  • TAF250/230 protein
  • TAFII-250 protein
  • TAFII250 protein
  • TAF[II]250 protein
  • TAF[[II]] protein
  • TAF[[II]]230 protein
  • Taf[[II]]250 protein
  • TAF[[II]]250/230 protein
  • TFIID protein
  • TFIID TAF250 protein
  • XDP protein

Protein level used designations for TAF1

CG17603-PA , CG17603-PB , CG17603-PC , CG17603-PD , CG17603-PE , TATA-associated factor 250 , TBP-associated factor , TBP-associated factor 250 , TBP-associated factor 250kD , TFIID 230 kda subunit , Taf1-PA , Taf1-PB , Taf1-PC , Taf1-PD , Taf1-PE , cell lethal , suppressor of Ras85D 3-5 , TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa , transcription initiation factor TFIID subunit 1 , transcription initiation factor TFIID, subunit TAF1 , TBP-associated factor 1-like , transcription initiation factor TFIID subunit 1-like , TAF(II)250 , TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, neuron specific isoform , TAFII-250 , TBP-associated factor 250 kDa , cell cycle gene 1 protein , cell cycle, G1 phase defect , p250 , transcription initiation factor TFIID 250 kDa subunit , complementation of cell cycle block, G1-to-S , transcription factor TFIID p250 polypeptide , Cell cycle gene 1 protein , Transcription initiation factor TFIID 250 kDa subunit

GENE ID SPECIES
40813 Drosophila melanogaster
736556 Pan troglodytes
5567420 Aedes aegypti
6035208 Culex quinquefasciatus
8250009 Micromonas sp. RCC299
5930833 Physcomitrella patens subsp. patens
5942503 Physcomitrella patens subsp. patens
100348935 Oryctolagus cuniculus
100457071 Pongo abelii
270627 Mus musculus
317256 Rattus norvegicus
6872 Homo sapiens
491950 Canis lupus familiaris
101838159 Mesocricetus auratus
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