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TATA-Binding Protein-Associated Phosphoprotein Proteins (DR1)

DR1 encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. Additionally we are shipping DR1 Antibodies (45) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DR1 13486 Q91WV0
Rat DR1 DR1 289881 Q5XI68
DR1 1810 Q01658
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Top DR1 Proteins at antibodies-online.com

Showing 9 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$756.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$385.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

DR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, , ,

Top referenced DR1 Proteins

  1. Human DR1 Protein expressed in Escherichia coli (E. coli) - ABIN667179 : Masson, Leimgruber, Creton, Collart: The dual control of TFIIB recruitment by NC2 is gene specific. in Nucleic acids research 2008 (PubMed)
    Show all 2 references for ABIN667179

More Proteins for TATA-Binding Protein-Associated Phosphoprotein (DR1) Interaction Partners

Human TATA-Binding Protein-Associated Phosphoprotein (DR1) interaction partners

  1. Knockdown of DR1 resulted in reductions of viral RNA and protein production, demonstrating that DR1 acts as a positive host factor in influenza A virus replication.

  2. The physiological functions of human Dr1 include regulation of polymerase III transcription.

  3. NC2 (show GTF2H5 Proteins) controls TBP (show TBP Proteins) binding and maintenance on DNA that is largely independent of a canonical TATA sequence

  4. the initiator core promoter element antagonizes repression of TATA-directed transcription by negative cofactor NC2 (show GTF2H5 Proteins)

  5. Data show that NC2beta is specifically involved in neuroblastoma (show ARHGEF16 Proteins) pathogenesis and may be considered a new neuroblastoma (show ARHGEF16 Proteins) biomarker.

  6. ATAC (show XCL1 Proteins) Is a GCN5 (show KAT2A Proteins)/PCAF (show KAT2B Proteins)-containing acetylase complex with a novel NC2 (show GTF2H5 Proteins)-like histone fold module that interacts with the TATA-binding protein (show TBP Proteins)

  7. heterodimerization with NC2alpha masks the nuclear localization signal in NC2beta, which prevents nuclear export of the NC2 (show GTF2H5 Proteins) complex

DR1 Protein Profile

Protein Summary

This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

Gene names and symbols associated with DR1

  • CG4185 gene product from transcript CG4185-RA (NC2beta)
  • TATA-BINDING PROTEIN-ASSOCIATED PHOSPHOPROTEIN (ECU11_0730)
  • TATA-binding protein-associated phosphoprotein (EDI_229030)
  • TATA-binding protein-associated phosphoprotein (PTRG_08168)
  • TATA-binding protein-associated phosphoprotein (Smp_160150)
  • TATA-binding protein-associated phosphoprotein (EBI_26279)
  • TATA-binding protein-associated phosphoprotein (EBI_23074)
  • TATA-binding protein-associated phosphoprotein (VDBG_02216)
  • down-regulator of transcription 1 (dr1)
  • down-regulator of transcription 1 (Dr1)
  • down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1)
  • 1700121L09Rik protein
  • BG:DS00929.3 protein
  • CG4185 protein
  • dDr1 protein
  • Dmel\\CG4185 protein
  • dNC2 protein
  • Dr1 protein
  • Dr1l protein
  • NC2 protein
  • NC2 beta protein
  • NC2-BETA protein
  • Nc2b protein
  • NC2beta protein
  • wu:fj15f04 protein
  • zgc:152914 protein

Protein level used designations for DR1

CG4185-PA , NC2beta-PA , TATA-BINDING PROTEIN-ASSOCIATED PHOSPHOPROTEIN , TATA-binding protein-associated phosphoprotein , protein Dr1 , NC2-beta , negative cofactor 2-beta

GENE ID SPECIES
34875 Drosophila melanogaster
860032 Encephalitozoon cuniculi GB-M1
5884241 Entamoeba dispar SAW760
6346449 Pyrenophora tritici-repentis Pt-1C-BFP
8346518 Schistosoma mansoni
8642100 Enterocytozoon bieneusi H348
8642196 Enterocytozoon bieneusi H348
9533879 Verticillium alfalfae VaMs.102
768171 Danio rerio
13486 Mus musculus
289881 Rattus norvegicus
1810 Homo sapiens
424496 Gallus gallus
479943 Canis lupus familiaris
613828 Bos taurus
Selected quality suppliers for DR1 Proteins (DR1)
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