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DR1 Products

(TATA-Binding Protein-Associated Phosphoprotein (DR1))

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This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeq, Jul 2008].

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Featured DR1 Categories

DR1 Antibodies

High quality antibodies with extensive validation data.

DR1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DR1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (7)
Cat. No. ABIN515068
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (3)
Cat. No. ABIN7011423
Quantity 60 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7165308
Quantity 100 μL
Datasheet Datasheet

Recommended DR1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125319
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352004
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352002
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our DR1 products

Deng, Malecová, Oelgeschläger, Roberts: "TFIIB recognition elements control the TFIIA-NC2 axis in transcriptional regulation." in: Molecular and cellular biology, Vol. 29, Issue 6, pp. 1389-400, (2009) (PubMed).

Synonyms and alternative names related to DR1

Negative Cofactor 2beta (NC2beta), TATA-BINDING PROTEIN-ASSOCIATED PHOSPHOPROTEIN (ECU11_0730), TATA-binding protein-associated phosphoprotein (EDI_229030), TATA-binding protein-associated phosphoprotein (PTRG_08168), putative tata-binding protein-associated phosphoprotein (Smp_160150), TATA-binding protein-associated phosphoprotein (EBI_26279), TATA-binding protein-associated phosphoprotein (EBI_23074), TATA-binding protein-associated phosphoprotein (VDBG_02216), down-regulator of transcription 1 (dr1), down-regulator of transcription 1 (Dr1), down-regulator of transcription 1, TBP-binding (negative cofactor 2) (Dr1), down-regulator of transcription 1 (DR1), 1700121L09Rik, BG:DS00929.3, CG4185, dDr1, Dmel\\CG4185, dNC2, Dr1, Dr1l, NC2, NC2 beta, NC2-BETA, Nc2b, NC2beta, wu:fj15f04, zgc:152914

Protein level used designations for DR1

  • CG4185-PA
  • NC2beta-PA
  • TATA-BINDING PROTEIN-ASSOCIATED PHOSPHOPROTEIN
  • TATA-binding protein-associated phosphoprotein
  • protein Dr1
  • NC2-beta
  • negative cofactor 2-beta
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