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The protein encoded by TBC1D10C has an N-terminal Rab-GTPase domain and a binding site at the C-terminus for calcineurin, and is an inhibitor of both the Ras signaling pathway and calcineurin, a phosphatase regulated by calcium and calmodulin. Additionally we are shipping TBC1 Domain Family, Member 10C Proteins (4) and many more products for this protein.
Showing 10 out of 35 products:
Human Polyclonal TBC1D10C Primary Antibody for IHC (p), WB - ABIN318913
White, Pasztor, Richardson, Zon: The gene encoding TBC1D1 with homology to the tre-2/USP6 oncogene, BUB2, and cdc16 maps to mouse chromosome 5 and human chromosome 4. in Cytogenetics and cell genetics 2000
Show all 2 references for 318913
Cow (Bovine) Polyclonal TBC1D10C Primary Antibody for WB - ABIN2786421
Pan, Sun, Kardian, Whartenby, Pardoll, Liu: Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin. in Nature 2007
Carabin as a new negative regulator of B-cell function, whose deficiency in B cells speeds up early B-cell responses
Carabin inhibits calcineurin (show PPP3CA Antibodies) and Ras and was identified by a yeast-two-hybrid screen with calcineurin (show PPP3CA Antibodies)
Carabin functions as an endogenous inhibitor of calcineurin (show PPP3CA Antibodies), Ras and CamKII (show CAMK2G Antibodies) kinase which resulted in protection against cardiac hypertrophy.
The protein encoded by this gene has an N-terminal Rab-GTPase domain and a binding site at the C-terminus for calcineurin, and is an inhibitor of both the Ras signaling pathway and calcineurin, a phosphatase regulated by calcium and calmodulin. Genes encoding similar proteins are located on chromosomes 16 and 22. Multiple transcript variants encoding different isoforms have been found for this gene.
TBC1 domain family, member 10C
, EBP50-PDZ interactor of 64 kD
, TBC1 domain family, member 10c