anti-T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1) Antibodies

Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Additionally we are shipping TIAM1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TIAM1 21844  
TIAM1 7074 Q13009
TIAM1 304109  
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Top anti-TIAM1 Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Sheep Un-conjugated WB 50 μg Log in to see 2 to 3 Days
$324.50
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Dog Goat Un-conjugated IHC (p) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated WB TIAM1 Antibody (C-term) (ABIN1881884) western blot analysis in ZR-75-1 cell line lysates (35 µg/lane). This demonstrates the TIAM1 antibody detected the TIAM1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Detection of Human and Mouse TIAM1 by Western Blot. Samples: Whole cell lysate from NIH-3T3 (50 mcg) and Jurkat (25 mcg) cells. Antibody: Affinity purified rabbit anti-TIAM1 antibody ABIN250682 used at 1 mcg/ml. Detection: Chemiluminescence with an exposure time of 2 minutes. Western Blot: TIAM1 Antibody  - Samples : Whole cell lysate from Mouse NIH3T3 (50 ug) and Jurkat (25 ug) cells. Antibody : Affinity purified rabbit anti-TIAM1 antibody used at 1 ug/ml. Detection : Chemiluminescence with an exposure time of 2 minutes. 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Goat Un-conjugated IHC (p) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of extract of various cells, using TIAM1 antibody. 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated IHC IF on 1 day- old mouse cortical cell culture using Rabbit antibody to T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1, TIAM1): whole serum (ABIN351007) at 1: 2000 dilution. DAPI counter stained. 100 μL Log in to see 7 to 8 Days
$454.67
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy3 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

TIAM1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TIAM1 Antibodies

  1. Human Polyclonal TIAM1 Primary Antibody for WB - ABIN1881884 : Yang, Lv, Liu, Liu, Yang, Hu: Up-regulation of Tiam1 and Rac1 correlates with poor prognosis in hepatocellular carcinoma. in Japanese journal of clinical oncology 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal TIAM1 Primary Antibody for WB - ABIN250682 : Redell, Zhao, Dash: Altered expression of miRNA-21 and its targets in the hippocampus after traumatic brain injury. in Journal of neuroscience research 2010 (PubMed)

More Antibodies against TIAM1 Interaction Partners

Mouse (Murine) T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1) interaction partners

  1. Findings indicate the role of Tiam1-Rac1-Nox2 (show CYBB Antibodies) signaling pathway in the onset of spontaneous diabetes in the type 1 diabetes NOD mouse model.

  2. Tiam1 and P-Rex1 promote Rac1 anti- and pro-migratory signalling cascades.

  3. S1466 of Tiam1 is a novel Cdk1 (show CDK1 Antibodies) site whose phosphorylation is required for Tiam1's mitotic function.

  4. endometrial Tiam1/Rac1 signal down-regulation along with miR (show MLXIP Antibodies)-22 up-regulation during embryo implantation window in the natural menstrual cycle may be one of the reasons for the failure of embryo implantation in patients with repeated implantation failure

  5. The MAP1B (show MAP1B Antibodies)-Tiam1-Rac1 relay is essential for spine structural plasticity and removal of AMPA (show GRIA3 Antibodies) receptors from synapses during long-term depression.

  6. Tiam1 is a regulator of the dopaminergic neurons development acting in the Wnt/Dvl/Rac1 pathway.

  7. Tiam1, a specific activator of the small GTPase (show RACGAP1 Antibodies) Rac (show AKT1 Antibodies), is required for the polarized outgrowth of protrusions in primary astrocytes during the initial phase of cell polarization after scratch-wounding monolayers of cells.

  8. Embryonic Tiam-1 expression plays a critical role during early brain development in mice.

  9. Study shows that the NR2C (show GRIN2C Antibodies) and Tiam1 maturation genes are synergistically controlled by the activity-dependent induction of Etv1 (show ETV1 Antibodies).

  10. These findings demonstrate a novel Shh pathway that regulates the actin cytoskeleton via Tiam1-Rac1 activation.

Human T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1) interaction partners

  1. Tiam1 expression is frequently up-regulated in breast cancer. Tiam1 expression correlated with clinicopathological parameters.

  2. In colorectal carcinoma TIAM1 suppresses tumor progression by regulating YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) activity.

  3. The expression of TIAM1 is closely related to the occurrence, development and metastasis of oral squamous cell carcinoma , and it can be used as a new marker for reflecting its biological behaviors.

  4. TIAM1 was aberrantly expressed in the oral squamous cell carcinoma group compared with the normal group. Furthermore, high expression of TIAM1 was significantly correlated with lymph node metastasis and the timing of recurrence.

  5. These data suggest a novel link between Tiam1 and RhoG/ILK /ELMO2 pathway as upstream effectors of the Rac1-mediated phagocytic process in trabecular meshwork cells.

  6. we have identified a novel reverse signaling pathway acting through Tiam1 and Rac (show AKT1 Antibodies) that promotes aggressive behavior in OSCC expressing S4D and PB1 (show SMR3A Antibodies).

  7. Taken together, these results suggest that the Par3 (show F2RL2 Antibodies) regulates invasion and metastasis in pancreatic cancers by controlling tight junction assembly via Tiam1.

  8. Tiam1 expression significantly increased in cholangiocarcinoma tissues, and increased along with the degree of malignancy of cholangiocarcinoma. Targeted silencing Tiam1 expression could inhibit proliferation and migration activity of cholangiocarcinoma cells.

  9. fibroblast expression patterns of Tiam1 and osteopontin (show SPP1 Antibodies) in human breast cancers show converse changes correlating with invasion, supporting the hypothesis that this pathway in tumor-associated fibroblasts regulates breast cancer invasiveness

  10. We identified T lymphoma invasion and metastasis 1 (TIAM1) gene as potential target of miR (show MLXIP Antibodies)-329 in gastric cancer

Cow (Bovine) T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1) interaction partners

  1. G protein betagamma subunits, Src kinase (show CSK Antibodies) and the GEF (show SLC2A4RG Antibodies) Tiam1 are upstream modulators of S1P (show MBTPS1 Antibodies)-mediated Rac1 activation, and Rac1 has a role in S1P (show MBTPS1 Antibodies)-mediated activation of PI 3 (show PI3 Antibodies)-kinase/Akt (show AKT1 Antibodies)/endothelial nitric-oxide synthase (show NOS3 Antibodies) signaling in vascular endothelial cells

TIAM1 Antigen Profile

Protein Summary

Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.

Gene names and symbols associated with TIAM1

  • T-cell lymphoma invasion and metastasis 1 (TIAM1) antibody
  • T-cell lymphoma invasion and metastasis 1a (tiam1a) antibody
  • T-cell lymphoma invasion and metastasis (tiam1) antibody
  • T-cell lymphoma invasion and metastasis 1 (LOC100338333) antibody
  • T-cell lymphoma invasion and metastasis 1 (tiam1) antibody
  • T cell lymphoma invasion and metastasis 1 (Tiam1) antibody
  • T-cell lymphoma invasion and metastasis 1 (Tiam1) antibody
  • AI847750 antibody
  • D16Ium10 antibody
  • D16Ium10e antibody
  • tiam1 antibody

Protein level used designations for TIAM1

T-cell lymphoma invasion and metastasis 1 , T-lymphoma invasion and metastasis-inducing protein 1 , T-lymphoma invasion and metastasis-inducing protein 1-like , t-lymphoma invasion and metastasis-inducing protein 1-like , TIAM-1 , human T-lymphoma invasion and metastasis inducing TIAM1 protein

GENE ID SPECIES
100052764 Equus caballus
473949 Pan troglodytes
567621 Danio rerio
702288 Macaca mulatta
734013 Xenopus (Silurana) tropicalis
100338333 Oryctolagus cuniculus
100390844 Callithrix jacchus
100431618 Pongo abelii
100540208 Meleagris gallopavo
100555790 Anolis carolinensis
21844 Mus musculus
7074 Homo sapiens
418491 Gallus gallus
487731 Canis lupus familiaris
536517 Bos taurus
304109 Rattus norvegicus
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