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Testis Derived Transcript (3 LIM Domains) Proteins (TES)

Cancer-associated chromosomal changes often involve regions containing fragile sites. Additionally we are shipping Testis Derived Transcript (3 LIM Domains) Antibodies (47) and Testis Derived Transcript (3 LIM Domains) Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TES 286916 P15242
TES 21753  
TES 26136 Q9UGI8
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Top Testis Derived Transcript (3 LIM Domains) Proteins at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$385.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,166.17
Details
Yeast Primates His tag   1 mg Log in to see 56 to 66 Days
$3,173.50
Details
Yeast Callithrix jacchus His tag   1 mg Log in to see 56 to 66 Days
$3,173.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,173.50
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$3,173.50
Details

TES Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Mouse (Murine)

Human , ,
,

Top referenced Testis Derived Transcript (3 LIM Domains) Proteins

  1. Human TES Protein expressed in Escherichia coli (E. coli) - ABIN667812 : Qiu, Zhu, Yuan, Yan, Yang, Kong: Frequent hypermethylation and loss of heterozygosity of the testis derived transcript gene in ovarian cancer. in Cancer science 2010 (PubMed)
    Show all 2 references for ABIN667812

More Proteins for Testis Derived Transcript (3 LIM Domains) (TES) Interaction Partners

Mouse (Murine) Testis Derived Transcript (3 LIM Domains) (TES) interaction partners

  1. zyxin (show ZYX Proteins) influences focal adhesion dynamics, that it recruits Tes and that this interaction is functional in regulating cell spreading.

  2. Testin is a mammalian gene involved in coordinated orientation of hair cells in the inner ear and in the development of the female reproductive tract.

  3. TES acts as a tumor suppressor in an established model of carcinogen-induced gastric cancer

Human Testis Derived Transcript (3 LIM Domains) (TES) interaction partners

  1. VASP (show VASP Proteins), zyxin (show ZYX Proteins) and TES are tension-dependent members of focal adherens junctions independent of the alpha-catenin (show CTNNA1 Proteins)-vinculin (show VCL Proteins) module.

  2. we confirm that the TES promoter is unmethylated in normal adult and fetal tissues. Re-expression of TESTIN protein in acute lymphoblastic leukemia cells using expression plasmid transfection results in rapid cell death or cell cycle arrest.

  3. Loss of TES gene expression is associated with nasopharyngeal carcinoma.

  4. findings suggest that the TES gene is a novel tumor suppressor gene

  5. TESTIN was hypermethylated in 43.7% endometrial cancer tissues (p < 0.001). Moreover, TESTIN hypermethylation was significantly correlated with advanced tumor stage, deep myometrial invasion and lymphatic node metastasis.

  6. Downregulation of TES was associated with breast cancer.

  7. TESTIN was commonly downregulated in human endometrial carcinoma and was associated with poor prognostic markers.

  8. A further significant correlation was observed between TES downregulation and the luminal B subtype independent of survivin (show BIRC5 Proteins) expression.

  9. TES, as a valuable marker of breast cancer prognosis, plays an important role in the development and progression of breast cancer. TES may be an effective novel target in breast cancer prevention and treatment.

  10. Low TES gene expression is associated with coronary artery disease.

Xenopus laevis Testis Derived Transcript (3 LIM Domains) (TES) interaction partners

  1. Prickle and tes act together to control axial elongation.

Testis Derived Transcript (3 LIM Domains) (TES) Protein Profile

Protein Summary

Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.

Gene names and symbols associated with TES

  • testis derived transcript (3 LIM domains) (tes)
  • testis derived transcript (3 LIM domains) (TES)
  • testin gene (Testin)
  • testin-like (LOC100407335)
  • testis derived transcript (Tes)
  • D6Ertd352e protein
  • DKFZp469E2320 protein
  • TES protein
  • Tes1 protein
  • Tes2 protein
  • TESS protein
  • TESS-2 protein
  • Testin protein
  • testin2 protein
  • xtes protein
  • zgc:92091 protein

Protein level used designations for TES

testin , testis derived transcript (3 LIM domains) , CMB-23 , testin-2 , testis derived transcript , TES1/TES2 , testin 2 , Testin-like protein , xtes

GENE ID SPECIES
403032 Danio rerio
448383 Xenopus (Silurana) tropicalis
706879 Macaca mulatta
780949 Monodelphis domestica
100126668 Papio anubis
100137158 Nomascus leucogenys
100173774 Pongo abelii
286916 Rattus norvegicus
100407335 Callithrix jacchus
21753 Mus musculus
500040 Rattus norvegicus
26136 Homo sapiens
475293 Canis lupus familiaris
100125376 Sus scrofa
534965 Bos taurus
100137197 Felis catus
395332 Gallus gallus
100071093 Equus caballus
100126564 Oryctolagus cuniculus
100126573 Ovis aries
463669 Pan troglodytes
380398 Xenopus laevis
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