anti-Transforming Growth Factor, beta-Induced, 68kDa (TGFBI) Antibodies

TGFBI encodes an RGD-containing protein that binds to type I, II and IV collagens. Additionally we are shipping Transforming Growth Factor, beta-Induced, 68kDa Kits (64) and Transforming Growth Factor, beta-Induced, 68kDa Proteins (24) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TGFBI 7045 Q15582
TGFBI 21810 P82198
TGFBI 116487  
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Top anti-Transforming Growth Factor, beta-Induced, 68kDa Antibodies at antibodies-online.com

Showing 10 out of 120 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TGFBI (arrow) using rabbit polyclonal TGFBI Antibody (N-term) . 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TGFBI gene. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated IF, WB Host: Rabbit Target Name: TGFBI Sample Type: Jurkat Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 2.5ug/mL Peptide Concentration: 2.0ug/mL Lysate Quantity: 25ug/lane Gel Concentration: 12% Species, Tissue/Cell Type:Human Cornea tissue (epithelium and stroma) Primary used and dilution: 1:400 100 μL Log in to see 2 to 3 Days
$229.00
Details
Dog Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of TGFBI (arrow) using rabbit polyclonal TGFBI Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TGFBI gene. TGFBI Antibody (N-term)  flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Chicken Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: Hela 7.5% SDS PAGE TGFBI antibody antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p), WB Immunohistochemistry-Paraffin: Beta Ig-h3/TGFBI Antibody [NBP1-47215] - NBP1-47215 (3.8ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Western Blot: Beta Ig-h3/TGFBI Antibody [NBP1-47215] - NBP1-47215 (0.3ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated IHC, IHC (p), SimWes, WB Immunohistochemistry: Beta Ig-h3/TGFBI Antibody [NBP1-88606] - Immunohistochemical staining of human small intestine shows strong cytoplasmic positivity in glandular cells. Simple Western: Beta Ig-h3/TGFBI Antibody [NBP1-88606] - Electropherogram image of the corresponding Simple Western lane view. Beta Ig-h3/TGFBI antibody was used at 1:25 dilution on U-251 MG lysate(s) respectively. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Bat Goat Un-conjugated IHC (p), ELISA, WB Human Kidney, Renal Duct: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 13 to 16 Days
$316.00
Details

TGFBI Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Transforming Growth Factor, beta-Induced, 68kDa Antibodies

  1. Human Polyclonal TGFBI Primary Antibody for EIA, WB - ABIN955176 : Edelstein, Huang, Harocopos, Waltman: Genotype of lattice corneal dystrophy (R124C mutation in TGFBI) in a patient presenting with features of avellino corneal dystrophy. in Cornea 2010 (PubMed)
    Show all 3 references for 955176

  2. Human Polyclonal TGFBI Primary Antibody for IHC, IHC (p) - ABIN4284120 : Kashyap, Harsha, Renuse, Pawar, Sahasrabuddhe, Kim, Marimuthu, Keerthikumar, Muthusamy, Kandasamy, Subbannayya, Prasad, Mahmood, Chaerkady, Meltzer, Kumar, Rustgi, Pandey: SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome. in Cancer biology & therapy 2011 (PubMed)
    Show all 3 references for 4284120

  3. Human Polyclonal TGFBI Primary Antibody for ELISA, IHC - ABIN4284118 : Zenteno, Correa-Gomez, Santacruz-Valdez, Suarez-Sanchez, Villanueva-Mendoza: Clinical and genetic features of TGFBI-linked corneal dystrophies in Mexican population: description of novel mutations and novel genotype-phenotype correlations. in Experimental eye research 2009 (PubMed)

More Antibodies against Transforming Growth Factor, beta-Induced, 68kDa Interaction Partners

Human Transforming Growth Factor, beta-Induced, 68kDa (TGFBI) interaction partners

  1. TGFBI and periostin (show POSTN Antibodies) act similarly in the heart in affecting fibrosis and disease responsiveness.

  2. The p.(Val113Ile) mutation results in an alteration of the atypical LCD phenotype associated with the p.(Leu558Pro) mutation. This represents only the second report of the alteration of the phenotype of a TGFBI dystrophy by a second, non-homozygous pathogenic mutation, and thus provides insight into the phenotype-genotype correlation of the TGFBI dystrophies.

  3. Our findings demonstrate that granular corneal dystrophy type 1 may present with a vortex pattern of anterior stromal deposits. Although this pattern of dystrophic deposits is not recognized by clinicians as a typical phenotype of GCD1, it is consistent with the production of the majority of the TGFBI protein by the corneal epithelium.

  4. The right cornea showed a higher number of lattice lines than the left cornea. Molecular analysis involving bidirectional complete sequencing demonstrated a novel T621P mutation in exon 14 of TGFBI.

  5. ig-h3, Peroxiredoxin-2 (show PRDX2 Antibodies), and NRF2 (show GABPA Antibodies) have roles in cervical carcinogenesis

  6. LASIK surgery of granular corneal dystrophy type 2 patients leads to accumulation and differential proteolytic processing TGFBI protein.

  7. High TGFBI expression in Esophageal squamous cell carcinoma is associated with hematogenous recurrence.

  8. We observed that knockdown of Cul4A was associated with increased sensitivity to gemcitabine through upregulation of TGFBI in lung cancer cells.

  9. TGFBIp expression is positively regulated by TGF-beta1 (show TGFB1 Antibodies) in corneal fibroblasts, whereas TGF-beta1 (show TGFB1 Antibodies)-induced miR (show MLXIP Antibodies)-21 and miR (show MLXIP Antibodies)-181a negatively regulate TGFBIp expression.

  10. Data suggest that periostin and TGFBI (transforming growth factor-beta induced protein) can be considered paralogs in some ways: structural homology, phylogeny, and functions in extracellular matrix formation/cell adhesion/cellular immunity. [REVIEW]

Mouse (Murine) Transforming Growth Factor, beta-Induced, 68kDa (TGFBI) interaction partners

  1. Data suggest that big-h3 protein (BIGH3 (show TGFB1 Antibodies)) acts as a tumor suppressor in the retina.

  2. TGF-beta (show TGFB1 Antibodies)-induced matricellular protein-null lungs displayed diminished elastic recoil and gas exchange efficiency

  3. the data suggest a model by which cytokine-induced Myt3 suppression leads to Tgfbi de-repression and subsequently to impaired islet-cell migration, revealing a novel role for Myt3 in regulating islet-cell migration.

  4. Studies reveal that growth hormone (GH (show GH1 Antibodies))increases TGFBI (show TGFB1 Antibodies) expression in a mouse and rat models of diabetic nephropathy (DN) which correlate with clinical results, and suggest that this mechanism can explain the podocytes depletion in DN.

  5. Tgfbi deficiency is associated with the degradation of cartilage matrix

  6. The results support a novel inflammatory pathway for diabetic retinopathy. This pathway is initiated by TGFbeta (show TGFB1 Antibodies) released from macrophages, which promotes synthesis and release of BIGH3 (show TGFB1 Antibodies) protein by REC (show ZDHHC2 Antibodies) and REC (show ZDHHC2 Antibodies) apoptosis.

  7. TGFBI is a potential risk gene for human diabetes.

  8. High blood TGFBIp levels were observed in cecal ligation and puncture (CLP)-induced septic mice. The absence of the TGFBIp gene in mice attenuated CLP-induced sepsis.

  9. Collectively, our findings indicate that betaig-h3 (show TGFB1 Antibodies) promotes the fibrogenic influence of TGFbeta (show TGFB1 Antibodies) signaling, neutralizing the prochondrogenic influence of the hypoxic-inducible factor 1 activated by the microenvironment of limb mesenchymal aggregates.

  10. the observed effect of TGFBI on bone mass and bone size was largely caused by the effect of TGFBI on periosteal bone formation

Zebrafish Transforming Growth Factor, beta-Induced, 68kDa (TGFBI) interaction partners

  1. This study shows that upregulation of bigh3 and bambia mRNA correlated with the process of fin regeneration and regulation of TGF-b signaling, suggesting a new role for these proteins.

  2. Results describe the distribution of TGFBI in the developing skeletal muscle of zebrafish embryos, and use antisense morpholino oligonucleotides to investigate the function of the endogenous protein.

Arabidopsis thaliana Transforming Growth Factor, beta-Induced, 68kDa (TGFBI) interaction partners

  1. downregulation of CSD2 (show TGFB1 Antibodies) by the heat-inducible miR398 is required for thermotolerance in Arabidopsis.

  2. Data indicate that in the MKK5 (show MAP2K5 Antibodies)-RNAi (RNA interference) lines, the induction of CSD1 and CSD2 (show TGFB1 Antibodies) as well as the activation of MKK5 (show MAP2K5 Antibodies) activity were completely arrested.

  3. Data indicate that transgenic plants expressing miR398-resistant forms of CSD1, CSD2 (show TGFB1 Antibodies) and CCS (show CCS Antibodies) under the control of their native promoters are more sensitive to heat stress.

  4. miR398 links expression of the three major chloroplast copper proteins, plastocyanin, CCS1 and Csd2 (show TGFB1 Antibodies), to copper availability.

  5. CSD2 (show TGFB1 Antibodies) expression is fine-tuned by miR398-directed mRNA cleavage.

  6. Results show that CSD1, but not CSD2 (show TGFB1 Antibodies), mRNA levels were negatively correlated with miR398 levels during ozone, salinity and biotic stress.

Transforming Growth Factor, beta-Induced, 68kDa (TGFBI) Antigen Profile

Protein Summary

This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.

Gene names and symbols associated with TGFBI

  • transforming growth factor, beta-induced, 68kDa (TGFBI) antibody
  • transforming growth factor, beta induced (Tgfbi) antibody
  • transforming growth factor, beta-induced, 68kDa (Tgfbi) antibody
  • transforming growth factor, beta-induced (tgfbi) antibody
  • copper/zinc superoxide dismutase 2 (CSD2) antibody
  • 68kDa antibody
  • AI181842 antibody
  • AI747162 antibody
  • Beta-ig antibody
  • Big-h3 antibody
  • BIGH3 antibody
  • CDB1 antibody
  • CDG2 antibody
  • CDGG1 antibody
  • COPPER/ZINC SUPEROXIDE DISMUTASE antibody
  • copper/zinc superoxide dismutase 2 antibody
  • CSD antibody
  • CSD1 antibody
  • CSD2 antibody
  • CSD3 antibody
  • CZSOD2 antibody
  • EBMD antibody
  • F24D13.2 antibody
  • F24D13_2 antibody
  • hm:zeh0933 antibody
  • LCD1 antibody
  • MP70 antibody
  • MP78 antibody
  • wu:fa13f05 antibody
  • zgc:110495 antibody

Protein level used designations for TGFBI

RGD-CAP , transforming growth factor-beta-induced protein ig-h3 , RGD-containing collagen-associated protein , beta ig-h3 , kerato-epithelin , transforming growth factor, beta induced, 68 kDa , transforming growth factor, beta induced , etID38199.14 , Transforming growth factor-beta-induced protein ig-h3 , transforming growth factor induced protein

GENE ID SPECIES
395897 Gallus gallus
7045 Homo sapiens
21810 Mus musculus
116487 Rattus norvegicus
100717287 Cavia porcellus
100519300 Sus scrofa
539596 Bos taurus
321421 Danio rerio
817365 Arabidopsis thaliana
100009230 Oryctolagus cuniculus
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