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Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) Proteins (TGM2)

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. Additionally we are shipping Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) Antibodies (282) and Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) Kits (36) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TGM2 7052 P21980
TGM2 21817 P21981
Rat TGM2 TGM2 56083  
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Top Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) Proteins at antibodies-online.com

Showing 10 out of 29 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Human Un-conjugated   100 μg Log in to see 4 to 5 Days
$135.63
Details
HOST_Escherichia coli (E. coli) Human His tag   10 mU Log in to see 2 to 3 Days
$203.70
Details
HOST_Baculovirus infected Insect Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$528.00
Details
HOST_Escherichia coli (E. coli) Mammalian Un-conjugated   250 μg Log in to see 7 to 9 Days
$849.29
Details
HOST_HEK-293 Cells Mouse His tag   50 μg Log in to see 5 Days
$522.50
Details

TGM2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, ,
Mouse (Murine) , ,

Top referenced Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) Proteins

  1. Human TGM2 Protein expressed in Wheat germ - ABIN1322636 : Velez V, Romano, McKown, Green, Zhang, Raab, Ryan, Hutnik, Frierson, Laurie: Tissue transglutaminase is a negative regulator of monomeric lacritin bioactivity. in Investigative ophthalmology & visual science 2013 (PubMed)

  2. Human TGM2 Protein expressed in - ABIN1047979 : Faye, Inforzato, Bignon, Hartmann, Muller, Ballut, Olsen, Day, Ricard-Blum: Transglutaminase-2: a new endostatin partner in the extracellular matrix of endothelial cells. in The Biochemical journal 2010 (PubMed)

More Proteins for Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) Interaction Partners

Human Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) interaction partners

  1. The frequency of TG2-specific plasma cells in the celiac lesion is dynamically regulated in response to gluten exposure.

  2. A gain-of-function mutation in P2X7R (show P2RX7 Proteins) associated with autoimmune disease caused enhanced TG2 externalization from cells, and this correlated with increased pore activity.

  3. We showed the appearance of transglutaminase (TG2) immunoreactivity in leukocytes in multiple sclerosis lesions, and particular in macrophages in rat chronic-relapsing experimental autoimmune encephalomyelitis.

  4. Transglutaminase 2 up-regulation is associated with RANKL/OPG (show TNFSF11 Proteins) pathway

  5. TG2 secreted in the tumor microenvironment orchestrates the cross-talk between cancer cells and stroma fundamentally affecting tumor growth.

  6. Results show no genetic association of the TGM2 gene with schizophrenia in the Chinese cohort.

  7. 3 biomarkers in 44 patients with in situ breast cancers were evaluated: TG2 (transglutaminase 2), HJURP (Holliday junction recognition protein (show HJURP Proteins)), and HIF-1alpha (hypoxia inducible factor-1 alpha (show HIF1A Proteins)).

  8. Data show that transglutaminase 2 (TG2)-mediated self-crosslinking sites locate to the catalytic core and C-terminal part of TG2.

  9. TG2 has an important role in maintaining cancer stem cell survival, invasive, and metastatic behavior in epidermal squamous cell carcinoma.

  10. miR (show MLXIP Proteins)-19 overexpression and subsequent decreased TG2 expression was linked to chromosome-13 amplification events, leading to altered invasive behavior in colorectal cancer cells.

Cow (Bovine) Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) interaction partners

  1. TG2 contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT (show AKT1 Proteins) signaling, likely via its serotonylation.

  2. An important role for TG2, mediated by intracellular calcium fluxes and HIF1A (show HIF1A Proteins), in hypoxia-induced pulmonary artery smooth muscle cells proliferation.

  3. externalized GTP (show AK3 Proteins)-bound TG2 serves as a molecular switch for differentiation of chondrocytes to a hypertrophic, calcifying phenotype in a manner that does not require either TG2 transamidation activity or fibronectin (show FN1 Proteins) binding

Pig (Porcine) Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) interaction partners

  1. small artery remodeling associated with chronic vasoconstriction depends on tissue-type transglutaminase.

Mouse (Murine) Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) interaction partners

  1. TG2 controls the formation of VEGF165-heparan sulfate proteoglycan complexes

  2. TG2 is a novel inhibitor of adipogenesis.

  3. LPS (show TLR4 Proteins)-induced TG2 was involved in the mechanism of pinocytosis and phagocytosis in microglia.

  4. Inhibition of tissue transglutaminase resulted in a reduced rate of compaction compared to controls during early remodeling (up to 2 days). In contrast, inhibition of lysyl oxidase (show LOX Proteins) did not alter the early compaction.

  5. TG2-deficient mice exhibited hyper inflammatory responses after being challenged with monosodium urate crystals.

  6. Data presented in this study show that TG2 plays a key role in cellular dynamics and consequently influences the energetic metabolism.

  7. TG2 functions as a critical signal for allergic lung responses.

  8. TG2 ablation had no effect on either motor or cognitive deficits, or on the weight loss.

  9. TG2 is an important mediator of endothelial cell inflammation and lung PMN (show TBCE Proteins) sequestration associated with intravascular coagulation and sepsis

  10. TG2 promotes neointima formation by mediating the PDGF (show PDGFA Proteins)-BB activation of the PDGFR (show PDGFRB Proteins)/Akt1 (show AKT1 Proteins) and beta-catenin (show CTNNB1 Proteins) pathways in vascular smooth muscle cells.

Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) Protein Profile

Protein Summary

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TGM2

  • transglutaminase 2, C polypeptide (Tgm2)
  • transglutaminase 2 (TGM2)
  • transglutaminase 2 (LOC100352148)
  • transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2)
  • transglutaminase 2b (tgm2b)
  • fc12b04 protein
  • G-ALPHA-h protein
  • GNAH protein
  • G[a]h protein
  • TG2 protein
  • TGase2 protein
  • TgaseII protein
  • TGC protein
  • TGL2 protein
  • TGM2 protein
  • tTG protein
  • tTGas protein
  • wu:fc12b04 protein
  • zgc:136700 protein

Protein level used designations for TGM2

TGase C , protein-glutamine gamma-glutamyltransferase 2 , C polypeptide, protein-glutamine-gamma-glutamyltransferase , TG(C) , TGase H , TGase-2 , TGase-H , protein-glutamine-gamma-glutamyltransferase , tissue transglutaminase , transglutaminase C , transglutaminase H , transglutaminase-2 , TGC , C polypeptide , TG C , tissue-type transglutaminase , transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)

GENE ID SPECIES
100379228 Cavia porcellus
7052 Homo sapiens
100352148 Oryctolagus cuniculus
396432 Gallus gallus
281528 Bos taurus
485867 Canis lupus familiaris
100127492 Sus scrofa
21817 Mus musculus
56083 Rattus norvegicus
323856 Danio rerio
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