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The protein encoded by TNFRSF19 is a member of the TNF-receptor superfamily. Additionally we are shipping Tumor Necrosis Factor Receptor Superfamily, Member 19 Antibodies (86) and Tumor Necrosis Factor Receptor Superfamily, Member 19 Kits (6) and many more products for this protein.
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Human TNFRSF19 Protein expressed in Human Cells - ABIN2005683
Hu, Tamada, Ni, Vincenz, Chen: Characterization of TNFRSF19, a novel member of the tumor necrosis factor receptor superfamily. in Genomics 2000
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Mouse (Murine) TNFRSF19 Protein expressed in Human Cells - ABIN2007405
Eby, Jasmin, Kumar, Sharma, Chaudhary: TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death. in The Journal of biological chemistry 2000
Show all 3 references for ABIN2007405
TNFRSF19 may contribute to the development of colorectal tumors with deregulated beta-catenin (show CTNNB1 Proteins) activity.
Results show aberrant expression and/or signaling by TROY as a contributor to the dispersion of glioblastoma cells and therapeutic resistance.
the association of RhoGDIalpha with TROY contributed to TROY-dependent RhoA (show RHOA Proteins) activation and neurite outgrowth inhibition after Nogo (show RTN4 Proteins)-66 stimulation.
TROY is up-regulated in human colorectal cancer cell lines and in intestinal tumors in mice. It functions as a negative modulator of the Wnt (show WNT2 Proteins) pathway in LGR5 (show LGR5 Proteins)-positive stem cells.
study demonstrated that TNFR2 (show TNFRSF1B Proteins) and TROY mRNA levels are enhanced in cutaneous squamous cell carcinoma cells compared to healthy ones in a Tunisian population
The FAM134B (show FAM134B Proteins) and TNFRSF19 showed a dramatically strong synergistic epistasis in explaining the genetic dissection of the susceptibility to complex vascular dementia.
TNFRSF19 overexpression in glioma cells activates Rac1 signaling in a Pyk2 (show PTK2B Proteins)-dependent manner to drive glioma cell invasion and migration
Findings provide new insights into the pathogenesis of NPC (show NPC1 Proteins) by highlighting the involvement of pathways related to TNFRSF19 and MDS1-EVI1 (show MECOM Proteins) in addition to HLA molecules.
TROY regulates melanoma growth.
the ternary complex of NgR (show RTN4R Proteins)/TROY/LINGO-1 (show LINGO1 Proteins) expressed on astrocytes, macrophages/microglia and neurones, by interacting with Nogo-A (show RTN4 Proteins) on oligodendrocytes, might modulate glial-neuronal interactions in demyelinating lesions of multiple sclerosis
High TROY expression is associated with glioblastoma cell invasion.
TROY negatively modulates remyelination in the central nervous system.
TROY is expressed in microglia, involved in their migration and targeted by propentofylline.
TROY plays some important roles in neurogenesis of embryonic stages.
This gene was a target of WNT (show WNT2 Proteins) signaling in the dorsal somite.
Analysis of expression patterns of eda (show EDA Proteins), edar (show EDAR Proteins) and tnfrsf19 in mouse embryogenesis.
Both mRNA and protein of TROY are detected in the olfactory bulb during embryogenesis; TROY expression is most intense in the inner layer. In the postnatal olfactory bulb, TROY-expressing cells are also detected in the glomerular layer.
Our results implicate TROY in mediating myelin inhibition, offering new insights into the molecular mechanisms of regeneration failure in the adult nervous system.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.
tumor necrosis factor receptor superfamily member 19
, tumor necrosis factor receptor superfamily, member 19
, tumor necrosis factor receptor superfamily member 19-like
, toxicity and JNK inducer
, Toxicity and JNK inducer