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Tumor Necrosis Factor Receptor Superfamily, Member 8 Proteins (TNFRSF8)

The protein encoded by TNFRSF8 is a member of the TNF-receptor superfamily. Additionally we are shipping TNFRSF8 Antibodies (571) and TNFRSF8 Kits (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNFRSF8 21941 Q60846
TNFRSF8 943 P28908
TNFRSF8 25069 P97525
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Top TNFRSF8 Proteins at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$286.00
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$319.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_HEK-293 Human His tag 50 μg Log in to see 2 to 3 Days
$630.00
Details
HOST_Human Cells Human His tag,Fc Tag 100 μg Log in to see 16 Days
$272.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_HEK-293 Human His tag   0.1 mg Log in to see 2 to 3 Days
$515.63
Details

TNFRSF8 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , , , , , ,
, , , , ,
Rat (Rattus)

Top referenced TNFRSF8 Proteins

  1. Human TNFRSF8 Protein expressed in HEK-293 Cells - ABIN2180740 : Ansieau, Scheffrahn, Mosialos, Brand, Duyster, Kaye, Harada, Dougall, Hübinger, Kieff, Herrmann, Leutz, Gruss: Tumor necrosis factor receptor-associated factor (TRAF)-1, TRAF-2, and TRAF-3 interact in vivo with the CD30 cytoplasmic domain; TRAF-2 mediates CD30-induced nuclear factor kappa B activation. in Proceedings of the National Academy of Sciences of the United States of America 1997 (PubMed)
    Show all 2 references for ABIN2180740

  2. Human TNFRSF8 Protein expressed in Escherichia coli (E. coli) - ABIN1098550 : Berro, Perry, Agrawal: Increased expression and activation of CD30 induce apoptosis in human blood eosinophils. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
    Show all 2 references for ABIN1098550

More Proteins for Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) Interaction Partners

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) interaction partners

  1. This study demonstrated the amelioration of MOG35-55 peptide-induced active EAE in CD30 KO mice. CD30 was expressed limitedly on CD4 (show CD4 Proteins) T cells at the induction phase of experimental autoimmune encephalomyelitis.

  2. Data indicate that CD30L (show TNFSF8 Proteins)/CD30 axis plays a modulatory role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE).

  3. role in the maintenance and activation of IL-17A (show IL17A Proteins)-producing gammadelta T cells

  4. These results suggest that CD30 signaling plays an important role in the activation of IL-17A (show IL17A Proteins)-producing Vgamma1(-) Vgamma4(-) gammadelta T cells bearing Vgamma6 at an early stage of BCG (show SLC11A1 Proteins) infection.

  5. Interference of the CD30-CD30L (show TNFSF8 Proteins) pathway reduces atherosclerosis development.

  6. CD30L (show TNFSF8 Proteins)/CD30 pathway acts as an accelerator of enteritis in a murine disease model

  7. role of CD30L (show TNFSF8 Proteins)/CD30 interactions in allergic rhinitis; results suggest that CD30L (show TNFSF8 Proteins) plays an important role in allergic rhinitis

  8. Abrogation of CD30 and OX40 (show TNFRSF4 Proteins) signals prevents autoimmune disease in FoxP3 (show FOXP3 Proteins)-deficient mice.

  9. Studies demonstrate that CD30L (show TNFSF8 Proteins)/CD30 signaling executed by the T-T cell interaction plays a critical role in Th17 cell differentiation.

  10. CD30 can signal in a completely TCR-independent fashion to induce IL-13 (show IL13 Proteins) production by effector T cells.

Human Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) interaction partners

  1. this review is focused on the role of CD30 receptor and p53 as novel targets for therapy in ALK+ ALCL, and also provides an update on their potential involvement in ALK+ ALCL pathogenesis

  2. Most angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma-not otherwise specified express variable levels of CD30.

  3. Upregulated expression of CD30 is commonly found in sclerosing angiomatoid nodular transformation of the spleen.

  4. Our results demonstrated significantly elevated sCD30 levels in AS patients compared to healthy controls (HCs (show HLCS Proteins)) with mean values of 32.0 +/- 12.2 and 24.9 +/- 8.0 ng/mL, (P(**) = 0.007), suggesting a p role of sCD30 in the pathogenesis of AS.

  5. With the introduction of the immunoconjugate brentuximab vedotin, the CD30 antigen has become an effectively targetable molecule. Therefore, we investigated the frequency and level of CD30 expression in post-transplant lymphoproliferative disorders.

  6. Data susggest that CD30 antigen may be useful as a prognostic factor and therapeutic target in extranodal natural killer/T-cell lymphoma (NKTCL).

  7. Data indicate that CD30 antigen downregulation and P-Glycoprotein (MDR1) upregulation are associated with drug resistance to brentuximab vedotin.

  8. Intralymphatic variant of ALCL and LyP (show PTPN22 Proteins) may be explained, at least in part, by a particular lymphotropism of the neoplastic cells of cutaneous CD30 lymphoproliferative disorders.

  9. BAG-3 (show BAG3 Proteins) expression correlated with increased HSP70 (show HSP70 Proteins) expression in a subset of systemic T cell lymphoma cases co-expressing the CD30 antigen.

  10. Single threonine residue at position 61 in CD30v that is critical for TRAF2 interaction, NFkappaB activation, and downstream CD30-NFkappaB-dependent phenotypes in hESCs was identified.

TNFRSF8 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene names and symbols associated with TNFRSF8

  • tumor necrosis factor receptor superfamily, member 8 (TNFRSF8)
  • tumor necrosis factor (ligand) superfamily, member 8 (TNFSF8)
  • tumor necrosis factor receptor superfamily, member 8 (Tnfrsf8)
  • Cd30 protein
  • D1S166E protein
  • Ki protein
  • Ki-1 protein
  • TNFRSF8 protein

Protein level used designations for TNFRSF8

tumor necrosis factor receptor superfamily member 8 , tumor necrosis factor receptor superfamily, member 8 , tumor necrosis factor ligand superfamily member 8 , tumor necrosis factor receptor superfamily member 8-like , CD30L receptor , lymphocyte activation antigen CD30 , Ki-1 antigen , cytokine receptor CD30 , Tumor necrosis factor superfamily member 8 , tumor necrosis factor superfamily, member CD30

GENE ID SPECIES
395090 Gallus gallus
457960 Pan troglodytes
487438 Canis lupus familiaris
574055 Sus scrofa
574056 Bos taurus
614780 Bos taurus
722773 Macaca mulatta
777365 Gallus gallus
100385465 Callithrix jacchus
100579424 Nomascus leucogenys
21941 Mus musculus
943 Homo sapiens
25069 Rattus norvegicus
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