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Tumor Suppressor Candidate 2 Proteins (TUSC2)

TUSC2 is a highly conserved lung cancer candidate gene. Additionally we are shipping Tumor Suppressor Candidate 2 Antibodies (44) and Tumor Suppressor Candidate 2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TUSC2 11334 O75896
Mouse TUSC2 TUSC2 80385 Q9WVF8
Rat TUSC2 TUSC2 501052  
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Top Tumor Suppressor Candidate 2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$486.07
Details

TUSC2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Tumor Suppressor Candidate 2 (TUSC2) Interaction Partners

Human Tumor Suppressor Candidate 2 (TUSC2) interaction partners

  1. FOXP1 (show FOXP1 Proteins), TP53INP1, TNFAIP3 (show TNFAIP3 Proteins), and TUSC2 were identified as miR (show MLXIP Proteins)-19a targets.

  2. The therapeutic activity of TUSC2 could extend the use of erlotinib to lung cancer patients with wildtype EGFR (show EGFR Proteins).

  3. TUSC2P and TUSC2 3'-UTR expression inhibits cell proliferation, survival, migration, invasion and colony formation, and increases tumor cell death. TUSC2P and TUSC2 3'-UTR bind to miRNAs and arrest their functions, leading to increased TUSC2 translation.

  4. The tumor suppressor gene TUSC2 (FUS1) sensitizes NSCLC to the AKT (show AKT1 Proteins) inhibitor MK2206 in LKB1 (show STK11 Proteins)-dependent manner.

  5. RNA sequence elements in FUS1 (show FUS Proteins) UTRs that regulate FUS1 (show FUS Proteins) protein express were identified.

  6. Absence of tumor suppressor FUS1 (show FUS Proteins) protein expression is associated with bone and soft tissue sarcomas.

  7. Data show that the recombinant FUS1 (show FUS Proteins) plasmid has been successfully cloned, which allows highly efficient FUS1 (show FUS Proteins) expression in E.coli strain Rosetta (DE3)2 plys.

  8. The goal of this study was to analyze possible involvement of TUSC2 in malignant pleural mesothelioma.

  9. Myristoylation is required for Fus1 (show FUS Proteins)-mediated tumor-suppressing activity and suggest a novel mechanism for the inactivation of tumor suppressors in lung cancer.

  10. These results suggest that miR (show MLXIP Proteins)-378 enhances cell survival, tumor growth, and angiogenesis through repression of the expression of two tumor suppressors, Sufu (show SUFUH Proteins) and Fus-1 (show FUS Proteins).

Mouse (Murine) Tumor Suppressor Candidate 2 (TUSC2) interaction partners

  1. Fus1 achieves its protective role in inflammation, autoimmunity, and cancer via the regulation of mitochondrial calcium and calcium-coupled parameters.

Tumor Suppressor Candidate 2 (TUSC2) Protein Profile

Protein Summary

This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available.

Gene names and symbols associated with TUSC2

  • tumor suppressor candidate 2 (TUSC2)
  • tumor suppressor candidate 2 (tusc2)
  • tumor suppressor candidate 2 (Tusc2)
  • 1190001E22Rik protein
  • AA407686 protein
  • C3orf11 protein
  • Fus1 protein
  • Lgcc protein
  • PAP protein
  • Pdap2 protein
  • TUSC2 protein

Protein level used designations for TUSC2

tumor suppressor candidate 2 , PDGFA associated protein 2 , PDGFA-associated protein 2 , fus-1 protein , fusion 1 protein , lung cancer candidiate, FUS

GENE ID SPECIES
702614 Macaca mulatta
100137709 Xenopus laevis
11334 Homo sapiens
80385 Mus musculus
501052 Rattus norvegicus
608576 Canis lupus familiaris
448842 Sus scrofa
100848754 Bos taurus
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