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Tyrosinase-Related Protein 1 Proteins (TYRP1)

TYRP1 encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Additionally we are shipping Tyrosinase-Related Protein 1 Antibodies (150) and Tyrosinase-Related Protein 1 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat TYRP1 TYRP1 89821 Q9QX01
TYRP1 7306 P17643
TYRP1 22178 P07147
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Top Tyrosinase-Related Protein 1 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Human Cells Human His tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Baculovirus infected Insect Cells Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Baculovirus infected Insect Cells Mouse His tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Fruit Fly Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

TYRP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, ,
Mouse (Murine) , ,
,

More Proteins for Tyrosinase-Related Protein 1 (TYRP1) Interaction Partners

Zebrafish Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. a mutation in tyrp1A, one of the two tyrp1 paralogs in zebrafish, causes melanophore death leading to a semi-dominant phenotype

  2. The Fugu tyrp1 promoter can direct transgene expression in a cell-type-specific manner in zebrafish. Our findings provide evidence supporting differential regulations of melanin-synthesizing genes in RPE (show RPE Proteins) cells and the NCDM in zebrafish.

Rabbit Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. A mutation in exon 2 of the TYRP1 gene leads to a premature stop codon at position 190 of the deduced amino acid sequence. Genotyping 203 rabbits of 32 different breeds identified this mutation only in brown Havana rabbits.

Human Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. Single nucleotide polymorphisms in TYRP1 gene is associated with multiple primary melanoma.

  2. Mutation in TYRP1 is associated with oculocutaneous albinism.

  3. Polymorphisms in 3'UTR of TYRP1 mRNA can affect TYRP1 mRNA regulation by miR (show MLXIP Proteins)-155 and its subsequent translation into protein. These SNPs can render TYRP1 mRNA and protein expression nonsusceptible to miR (show MLXIP Proteins)-155 activity

  4. These data suggest that UVB-stimulated Ucn1 contributes to TRP1 production via the transcription of both Nurr-1 and Nur77. Ucn1, produced in melanoma cells, acts on melanoma cells themselves in an autocrine manner.

  5. These data indicate that galectin-3 (show LGALS3 Proteins) is a regulatory component in melanin synthesis affecting the expression of Tyrp-1.

  6. p53 (show TP53 Proteins) regulation by TRP2 (show DCT Proteins) is not pervasive in melanoma.

  7. Due to mutation in Tyrp1 protein, it became more rigid and might disturb the structural conformation and catalytic function of the structure and might also play a significant role in inducing oculocutaneous albinism type III.

  8. in human melanoma HMV-II cells both CRF (show CRH Proteins) and Ucn1 regulate TRP1 (show PRSS1 Proteins) gene expression via Nurr-1 (show NR4A2 Proteins)/Nur77 (show NR4A1 Proteins) production, independent of pro-opiomelanocortin (show POMC Proteins) or alpha-melanocyte-stimulating hormone (show POMC Proteins) stimulation.

  9. High TYRP1/S100B (show S100B Proteins) mRNA expression in lymph node metastases from melanoma patients is associated with unfavourable clinical outcome.

  10. We report four Pakistani albinism mutations, including three SLC45A2 (show SLC45A2 Proteins) alleles and one 22-nucleotide deletion in TYRP1.

Pig (Porcine) Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. A 6-bp deletion in the TYRP1 gene causes the brown colouration phenotype in Chinese indigenous pigs.

Cow (Bovine) Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. Sequence analysis revealed variation in the TYRP1 (exon 5) and MC1R genes; restriction enzyme analysis of these two genes could distinguish between different colours of Hanwoo cattle.

Mouse (Murine) Tyrosinase-Related Protein 1 (TYRP1) interaction partners

  1. Genetic modulators of IOP thus may be independently identified using the full array of BXD mice without concern for the presence of transillumination defect or mutations in Typr1 and/or Gpnmb.

  2. the results from the present study demonstrate that the MA extract increases melanogenesis through the upregulation of TRP-1 (show TRPC1 Proteins) protein expression by post-transcriptional control in B16F10 cells

  3. Studied upregulation by Kaliziri extract of tyrosinase (show TYR Proteins), TRP-1 (show TRPC1 Proteins), TRP-2 (show DCT Proteins) and MITF (show MITF Proteins) expression in murine B16 melanoma cells.

  4. The SNARE (show VTI1B Proteins) machinery composed of VAMP7 (show VAMP7 Proteins) on Tyrp1-containing vesicles and syntaxin-3 (show STX3 Proteins) and SNAP23 (show SNAP23 Proteins) on melanosomes regulates Tyrp1 trafficking to the melanosome in melanocytes.

  5. Addition of a TRP-1 (show TRPC1 Proteins)-directed monoclonal antibody to the treatment protocol for B16F10 skin melanoma mediates eradication of subcutaneous lesions.

  6. analysis of tyrosinase-related protein 1 in mouse melanocytes at early embryonic stage

  7. GILT (show IFI30 Proteins)-deficient mice have an increase in TRP1 (show TRPC1 Proteins)-specific regulatory T (Treg) cells compared with TRP1 (show TRPC1 Proteins)-deficient mice, and depletion of Treg cells partially restores the ability of GILT (show IFI30 Proteins)-deficient TRP1 (show TRPC1 Proteins)-specific CD4 (show CD4 Proteins)(+) T cells to induce vitiligo (show MITF Proteins).

  8. The Tyrp1b mutation modifies the pathways and gene networks in which Tyrp1 functions.

  9. DNA vaccination with a melanoma-shared antigen Trp1 (show TRPC1 Proteins), combined with systemic TGF-beta (show TGFB1 Proteins) blockade during the perioperative period of primary tumor resection, confers protection against B16 melanoma.

  10. both the Rab32 (show RAB32 Proteins)/38 binding activity and VAMP7 (show VAMP7 Proteins) binding activity of Varp (show ANKRD27 Proteins) are essential for trafficking of Tyrp1 in melanocytes but activation of Rab21 (show RAB21 Proteins) by the VPS9 domain is not necessary for Tyrp1 trafficking

Tyrosinase-Related Protein 1 (TYRP1) Protein Profile

Protein Summary

This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.

Gene names and symbols associated with TYRP1

  • tyrosinase-related protein 1b (tyrp1b)
  • tyrosinase-related protein 1 (TYRP1)
  • tyrosinase-related protein 1 (tyrp1)
  • tyrosinase-related protein 1 (LOC100136490)
  • tyrosinase-related protein 1 (tyrp-1)
  • tyrosinase-related protein 1 (LOC100218715)
  • tyrosinase-related protein 1 (LOC100342170)
  • transient receptor potential cation channel, subfamily C, member 1 (Trpc1)
  • tyrosinase-related protein 1 (Tyrp1)
  • tyrosinase-related protein 1a (tyrp1a)
  • B protein
  • b-PROTEIN protein
  • brown protein
  • CAS2 protein
  • CATB protein
  • GP75 protein
  • hm:zeh0659 protein
  • isa protein
  • OCA3 protein
  • TRP protein
  • TRP-1 protein
  • TRP1 protein
  • Trrp1 protein
  • Tyrp protein
  • tyrp-1 protein
  • TYRP1 protein
  • zgc:100893 protein

Protein level used designations for TYRP1

5,6-dihydroxyindole-2-carboxylic acid oxidase , oca3 , tyrosinase-related protein 1 , 5,6-dihydroxyindole-2-carboxylic acid oxidase-like , TRP-1 , short transient receptor potential channel 1 , transient receptor protein 1 , DHICA oxidase , catalase B , glycoprotein 75 , melanoma antigen gp75 , TRP1 , tyrosinase-related protein-1 , brown locus protein , iris stromal atrophy , tyrosine phosphatase 1, same as B (Brown)

GENE ID SPECIES
437022 Danio rerio
464994 Pan troglodytes
549230 Xenopus (Silurana) tropicalis
554339 Felis catus
714646 Macaca mulatta
100033886 Equus caballus
100034666 Ovis aries
100136490 Salmo salar
100136925 Salmo salar
100218715 Taeniopygia guttata
100342170 Oryctolagus cuniculus
100396341 Callithrix jacchus
100460406 Pongo abelii
100590830 Nomascus leucogenys
89821 Rattus norvegicus
7306 Homo sapiens
395913 Gallus gallus
403479 Canis lupus familiaris
574065 Sus scrofa
282105 Bos taurus
22178 Mus musculus
298182 Rattus norvegicus
380184 Xenopus laevis
100333145 Danio rerio
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