anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) Antibodies

U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. Additionally we are shipping U2 Small Nuclear RNA Auxiliary Factor 2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
U2AF59 22185 P26369
U2AF59 11338 P26368
U2AF59 308335  
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Top anti-U2 Small Nuclear RNA Auxiliary Factor 2 Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-U2AF2 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-U2AF2 <br /> Antibody Titration: 1.25 µg/mL <br /> Positive Control: Jurkat cell lysate <br /> U2AF2 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-U2AF2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: HepG2 cell lysate There is BioGPS gene expression data showing that U2AF2 is expressed in HepG2 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB U2AF2 Antibody (N-term) (ABIN658504) western blot analysis in Jurkat cell line lysates (35 µg/lane). This demonstrates the U2AF2 antibody detected the U2AF2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of U2AF65 staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody Western blot analysis of U2AF65 expression in Jurkat (A), SW620 (B), mouse spleen (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB U2AF2 antibody used at 1.25 ug/ml to detect target protein. 100 μg Log in to see 2 to 3 Days
$388.93
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated WB Western Blot: U2AF2 Antibody [NBP1-57251] - Reccomended Titration: 1.25 ug/ml Positive Control: Jurkat cell lysate U2AF2 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Western Blot: U2AF2 Antibody [NBP1-57251] - Sample Tissue: Human Jurkat Antibody Dilution: 1.0 ug/ml 100 μL Log in to see 8 to 11 Days
$408.19
Details

U2AF59 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human
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Rat (Rattus)


Top referenced anti-U2 Small Nuclear RNA Auxiliary Factor 2 Antibodies

  1. Cow (Bovine) Polyclonal U2AF59 Primary Antibody for WB - ABIN2778722 : Sickmier, Frato, Kielkopf: Crystallization and preliminary X-ray analysis of a U2AF65 variant in complex with a polypyrimidine-tract analogue by use of protein engineering. in Acta crystallographica. Section F, Structural biology and crystallization communications 2006 (PubMed)

More Antibodies against U2 Small Nuclear RNA Auxiliary Factor 2 Interaction Partners

Mouse (Murine) U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) interaction partners

  1. Perturbation of U2AF65/NXF1-mediated RNA nuclear export enhances RNA tox (show NXF1 Antibodies)icity in polyQ diseases.

  2. dephosphorylation of pS776-ATXN1 (show ATXN1 Antibodies) by PP2A (show PPP2R2B Antibodies) regulates the interaction of ATXN1 (show ATXN1 Antibodies) with the splicing factors RBM17 (show RBM17 Antibodies) and U2AF65

  3. Using a yeast two-hybrid system, we found fourteen U2AF(65)-interacting proteins. The validity of the screen was confirmed by identification of five known U2AF(65)-interacting proteins, including its heterodimeric partner, U2AF(35 (show U2AF1 Antibodies)).

Xenopus laevis U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) interaction partners

  1. In vivo binding of U2AF(65) to a polypyrimidine tract requires a flexible RNA backbone.

Human U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) interaction partners

  1. These findings uncovered a hitherto unappreciated function of CD82 (show CD82 Antibodies) in severing the linkage between U2AF2-mediated CD44 (show CD44 Antibodies) alternative splicing and cancer aggressiveness, with potential prognostic and therapeutic implications in melanoma

  2. JMJD6 (show JMJD6 Antibodies) regulated a large set of alternative splicing events, and importantly, its regulated splicing events were significantly overlapped those controlled by U2AF65.

  3. This study therefore establishes a structural basis for specific UHM-ULM interactions by splicing factors such as U2AF35 (show U2AF1 Antibodies), U2AF65, RBM39 (show RBM39 Antibodies) and SF3b155 (show SF3B1 Antibodies), and a platform for continued studies of intermolecular interactions governing disease-related alternative splicing in eukaryotic cells.

  4. The U2AF(65) linker residues between the dual RNA recognition motifs (RRMs) recognize the central nucleotide, whereas the N- and C-terminal RRM extensions recognize the 3' terminus and third nucleotide.

  5. Nuclear retention of full-length HTT (show HTT Antibodies) RNA is mediated by splicing factors MBNL1 (show MBNL1 Antibodies) and U2AF65

  6. U2AF(65) possesses a splicing Inhibitory function that leads to alternative exon skipping.

  7. The spatial distribution of U2AF65 conformations is found to be highly anisotropic, comprising significantly populated interdomain contacts that appear to be electrostatic in origin.

  8. reduced U2AF(65) binding is a molecular consequence of disease-relevant mutations, and a structure-guided U2AF(65) variant is capable of manipulating gene expression in eukaryotic cells

  9. We demonstrated that PRPF40B interacts directly with SF1 and associates with U2AF(65

  10. U2AF65 represents a new route for modulating TRF1 (show TERF1 Antibodies) function at telomeres.

U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) Antigen Profile

Protein Summary

U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.

Gene names and symbols associated with U2AF59

  • U2 small nuclear RNA auxiliary factor 2 (u2af2) antibody
  • U2 small nuclear RNA auxiliary factor 2 (U2AF2) antibody
  • RNA recognition motif-containing protein RRM (u2af2) antibody
  • Splicing factor U2AF 65 kDa subunit (u2af2) antibody
  • U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 (U2af2) antibody
  • U2 small nuclear RNA auxiliary factor 2 (U2af2) antibody
  • 65kDa antibody
  • DDBDRAFT_0186947 antibody
  • DDBDRAFT_0233353 antibody
  • DDB_0186947 antibody
  • DDB_0233353 antibody
  • U2AF2 antibody
  • U2AF65 antibody

Protein level used designations for U2AF59

U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 , U2 small nuclear RNA auxiliary factor 2 , RNA-binding region RNP-1 domain-containing protein , U2 snRNP auxiliary factor large subunit , Splicing factor U2AF 65 kDa subunit , U2 auxiliary factor 65 kDa subunit , U2 small nuclear ribonucleoprotein auxiliary factor (U2AF), 65 kDa , splicing factor U2AF 65 kDa subunit , splicing factor U2AF large chain , U2 (RNU2) small nuclear RNA auxiliary factor 2 , U2 small nuclear ribonucleoprotein auxiliary factor (65kD) , hU2AF65

GENE ID SPECIES
549752 Xenopus (Silurana) tropicalis
703269 Macaca mulatta
8625590 Dictyostelium discoideum AX4
100380519 Salmo salar
22185 Mus musculus
380287 Xenopus laevis
11338 Homo sapiens
100687048 Canis lupus familiaris
507895 Bos taurus
308335 Rattus norvegicus
Selected quality suppliers for anti-U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) Antibodies
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