Ubiquitin Specific Peptidase 22 Proteins (USP22)

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Additionally we are shipping USP22 Antibodies (87) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
USP22 23326 Q9UPT9
USP22 216825 Q5DU02
Rat USP22 USP22 303201  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top USP22 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_Insect cells (Sf21) Human His tag   50 μg Log in to see 5 to 8 Days
$568.05
Details

USP22 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for Ubiquitin Specific Peptidase 22 (USP22) Interaction Partners

Fruit Fly (Drosophila melanogaster) Ubiquitin Specific Peptidase 22 (USP22) interaction partners

  1. Loss of Ataxin-7 results in a toxic gain of activity of the Non-stop deubiquitinase.

  2. Data establish that Nonstop actually functions as an ubiquitin (show UBA52 Proteins) protease to control the levels of ubiquitinated histone H2B in flies. We further establish that Nonstop is the functional homolog of yeast Ubp8

  3. 3 additional subunits of TFTC/STAGA (dSgf11, non-stop, & en(y)2) help form the deubiquitination module. This module is an enhancer of position effect variegation in Drosophila.

Human Ubiquitin Specific Peptidase 22 (USP22) interaction partners

  1. we demonstrated that USP22 was highly expressed in OS tissues and cells lines. Downregulation of USP22 inhibited OS cell proliferation, invasion, and EMT (show ITK Proteins) in vitro. In addition, downregulation of USP22 suppressed OS tumor growth and metastasis in vivo.

  2. In breast cancer cell lines USP22 increases c-Myc (show MYC Proteins) stability through c-Myc (show MYC Proteins) deubiquitination, which is closely correlated with breast cancer progression.

  3. that nuclear GSK3beta- and USP22-mediated KDM1A (show KDM1A Proteins) stabilization is essential for glioblastoma tumorigenesis

  4. findings suggest that USP22 may be involved in hepatocellular carcinoma progression in cooperation with survivin (show BIRC5 Proteins).

  5. These findings provide evidence that high USP22 expression might be important in tumor progression and serves as an independent molecular marker for poor hepatocellular carcinoma prognosis

  6. USP22 attenuated the invasion capacity of colon cancer cells by inhibiting the STAT3 (show STAT3 Proteins)/MMP9 (show MMP9 Proteins) signaling pathway.

  7. Our data indicated that USP22 may promote lung adenocarcinoma cell invasion by the induction of EMT (show ITK Proteins).

  8. Data show that the aggregates formed by polyQ-expanded ataxin 7 sequester ubiquitin-specific protease (USP22) through specific interactions.

  9. the deubiquitinating enzyme activity of USP22 is necessary for regulating HeLa cell growth, and it promotes cell proliferation via the c-Myc (show MYC Proteins)/cyclin D2 (show CCND2 Proteins), BMI-1 (show BMI1 Proteins) and p53 (show TP53 Proteins) pathways in HeLa cells

  10. ShRNA-mediated silencing of the ubiquitin-specific protease 22 gene restrained cell progression and affected the Akt (show AKT1 Proteins) pathway in nasopharyngeal carcinoma.

Mouse (Murine) Ubiquitin Specific Peptidase 22 (USP22) interaction partners

  1. high D-glucose induces increased expression of USP22 in cultured podocytes and diabetic rats. USP22 inhibition confers a protective effect against high glucose-induced podocyte depletion, apoptosis and inflammation.

  2. that nuclear GSK3beta- and USP22-mediated KDM1A (show KDM1A Proteins) stabilization is essential for glioblastoma tumorigenesis

  3. Usp22 deficiency impairs intestinal epithelial lineage specification.

  4. USP22 is a transcriptional repressor of the locus encoding the core pluripotency factor sex-determining region Y-box 2 (SOX2 (show SOX2 Proteins)) in embryonic stem cells.

  5. Genetic deletion of the usp22 gene results in Sirt1 (show SIRT1 Proteins) instability, elevated p53 (show TP53 Proteins) transcriptional activity and early embryonic lethality.

USP22 Protein Profile

Protein Summary

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators, where it is required for transcription (By similarity).

Gene names and symbols associated with USP22

  • ubiquitin specific peptidase 22 (USP22)
  • ubiquitin specific peptidase 22 (usp22)
  • non-stop (not)
  • hypothetical LOC454511 (USP22)
  • ubiquitin specific protease 22 (USP22)
  • universal stress protein (usp22)
  • ubiquitin specific peptidase 22 (Usp22)
  • AI427806 protein
  • anon-WO0257455.9 protein
  • CG4166 protein
  • Dmel\\CG4166 protein
  • i155 protein
  • l(3)02069 protein
  • l(3)j9A6 protein
  • nonstop protein
  • NOT protein
  • UBP8 protein
  • Upb8 protein
  • USP3L protein
  • USP22 protein
  • zgc:136342 protein

Protein level used designations for USP22

ubiquitin specific peptidase 22 , ubiquitin thiolesterase 22 , ubiquitin carboxyl-terminal hydrolase 22-like , CG4166-PB , nonstop , not-PB , ubiquitin specific protease 22 , universal stress protein , deubiquitinating enzyme 22 , ubiquitin carboxyl-terminal hydrolase 22 , ubiquitin thioesterase 22 , ubiquitin-specific processing protease 22 , ubiquitin-specific-processing protease 22

GENE ID SPECIES
712098 Macaca mulatta
100053238 Equus caballus
100340977 Oryctolagus cuniculus
100379835 Xenopus (Silurana) tropicalis
100456449 Pongo abelii
100476428 Ailuropoda melanoleuca
40030 Drosophila melanogaster
454511 Pan troglodytes
694018 Macaca mulatta
3129313 Haloarcula marismortui ATCC 43049
23326 Homo sapiens
216825 Mus musculus
692275 Danio rerio
509694 Bos taurus
303201 Rattus norvegicus
416501 Gallus gallus
609588 Canis lupus familiaris
Selected quality suppliers for USP22 Proteins (USP22)
Did you look for something else?