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Ubiquitin-Conjugating Enzyme E2D 3 Proteins (UBE2D3)

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2D 3 Antibodies (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UBE2D3 7323 P61077
Mouse UBE2D3 UBE2D3 66105 P61079
UBE2D3 81920 P61078
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Top Ubiquitin-Conjugating Enzyme E2D 3 Proteins at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag   3 nM Log in to see 2 to 3 Days
$330.75
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 2 to 3 Days
$393.75
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 5 Days
$137.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,321.00
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,321.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,321.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$382.86
Details

UBE2D3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus)

Top referenced Ubiquitin-Conjugating Enzyme E2D 3 Proteins

  1. Human UBE2D3 Protein expressed in Escherichia coli (E. coli) - ABIN667596 : Gonen, Bercovich, Orian, Carrano, Takizawa, Yamanaka, Pagano, Iwai, Ciechanover: Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkappaBalpha. in The Journal of biological chemistry 1999 (PubMed)
    Show all 2 references for ABIN667596

More Proteins for Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3) Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3) interaction partners

  1. Data show that ubiquitin E2 enzymes UBE2D1 (show UBE2D1 Proteins)/2/3 and E3 ligase RNF138 (show RNF138 Proteins) accumulate at DNA-damage sites and act at early resection stages by promoting CtIP (show RBBP8 Proteins) protein ubiquitylation and accrual.

  2. These data reveal novel insights into the Otub1 (show OTUB1 Proteins) inhibition of E2 wherein monoubiquitination promotes the interaction of Otub1 (show OTUB1 Proteins) with UbcH5 (show UBE2D1 Proteins) and the function to suppress it.

  3. UbcH5c~Ubiqitin binding stabilizes an active conformation of the Shigella flexneri OspG kinase, greatly enhancing its activity.

  4. UBE2D3 participates in the process of radiosensitivity in human breast cancer cells by regulating TERT (show TERT Proteins) and cyclin D1 (show CCND1 Proteins).

  5. although a reduction in interdomain dynamics of UbcH5c~Ub is observed upon binding to E4B, Ub retains an extensive degree of flexibility

  6. The crystal structure of a complex of the Bmi1 (show BMI1 Proteins)/Ring1b (show RNF2 Proteins) RING-RING heterodimer & UbcH5c shows that UbcH5c interacts with Ring1b (show RNF2 Proteins) only.

  7. UbcH5c approximately Ub conjugate populates an array of extended conformations, and the population of Ubc13 (show UBE2N Proteins) approximately Ub conjugates favors a closed conformation in which the hydrophobic surface of Ub faces helix 2 of Ubc13 (show UBE2N Proteins)

  8. determined structures of E4B U box free and bound to UbcH5c and Ubc4 (show UBE2D2 Proteins) E2s; findings show E4B U box is a monomer stabilized by a network of hydrogen bonds; findings suggest allosteric regulation of UbcH5c and Ubc4 (show UBE2D2 Proteins) by E4B U box

  9. Combined Actions of UbcH5c and Cdc34 (show CDC34 Proteins) Promote Rapid and Efficient Polyubiquitination of IkBa (show NFKBIA Proteins)

  10. role of WW3 and WW4 domains of Nedd4-2 in dopamine transporter ubiquitination was demonstrated; siRNA analysis demonstrated that this polyubiquitination is mediated by Nedd4-2 cooperation with UBE2D and UBE2L3 E2 ubiquitin-conjugating enzymes

Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3) Protein Profile

Protein Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

Gene names and symbols associated with UBE2D3

  • ubiquitin-conjugating enzyme E2D 3 (UBE2D3)
  • ubiquitin-conjugating enzyme E2D 3 (LOC100223566)
  • ubiquitin-conjugating enzyme E2D 3 (LOC100347511)
  • ubiquitin-conjugating enzyme E2D 3 (ube2d3)
  • ubiquitin-conjugating enzyme E2D 3 (Ube2d3)
  • 1100001F19Rik protein
  • 9430029A22Rik protein
  • AA414951 protein
  • E2(17)KB3 protein
  • eff protein
  • fb36f02 protein
  • UBC4/5 protein
  • UBCH5C protein
  • ube2d2 protein
  • ube2d3.1 protein
  • UBE2D3P protein
  • wu:fb36f02 protein
  • xubc4 protein
  • zgc:56340 protein

Protein level used designations for UBE2D3

ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) , ubiquitin-conjugating enzyme E2D 3 , ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog) , E2(17)KB 3 , PRO2116 , ubiquitin carrier protein D3 , ubiquitin-conjugating enzyme E2 D3 , ubiquitin-conjugating enzyme E2(17)KB 3 , ubiquitin-conjugating enzyme E2-17 kDa 3 , ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5) , ubiquitin-protein ligase D3 , ubiquitin-conjugating enzyme E2D 2 , ubiquitin carrier protein 4 , ubiquitin carrier protein D2 , ubiquitin conjugating enzyme E2 , ubiquitin-conjugating enzyme E2 D2 , ubiquitin-protein ligase D2 , PAPase , phosphoarginine phosphatase

GENE ID SPECIES
745118 Pan troglodytes
100223566 Taeniopygia guttata
100347511 Oryctolagus cuniculus
548818 Xenopus (Silurana) tropicalis
7323 Homo sapiens
321832 Danio rerio
403384 Xenopus laevis
422713 Gallus gallus
326583 Bos taurus
66105 Mus musculus
81920 Rattus norvegicus
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