UBE2D3 Protein (AA 1-149) (His tag)
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- Target See all UBE2D3 Proteins
- UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-149
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UBE2D3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- UBE2D3, 1-149aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT
- Storage
- 4 °C
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- Target
- UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))
- Alternative Name
- UBE2D3 (UBE2D3 Products)
- Synonyms
- E2(17)KB3 Protein, UBC4/5 Protein, UBCH5C Protein, eff Protein, fb36f02 Protein, wu:fb36f02 Protein, zgc:56340 Protein, 1100001F19Rik Protein, 9430029A22Rik Protein, AA414951 Protein, UBE2D3P Protein, Xubc4 Protein, e2(17)kb3 Protein, ubc4/5 Protein, ubch5c Protein, ube2d3.1 Protein, ube2d2 Protein, xubc4 Protein, wu:fj13d01 Protein, zgc:73200 Protein, ubiquitin conjugating enzyme E2 D3 Protein, ubiquitin-conjugating enzyme E2D 3 Protein, ubiquitin conjugating enzyme E2 D3 L homeolog Protein, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like Protein, UBE2D3 Protein, ube2d3 Protein, Ube2d3 Protein, LOC100223566 Protein, ube2d3.L Protein, ube2d2l Protein
- Background
- UBE2D3, also known as ubiquitin-conjugating enzyme E2 D3. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Recombinant human UBE2D3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Ubiquitin-conjugating enzyme E2 D3, UBC5C, UBCH5C. NCBI no.: NP_871622
- Molecular Weight
- 19.1 kDa (169aa), confirmed by MALDI-TOF
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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