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Ubiquitin-Like Modifier Activating Enzyme 7 Proteins (UBA7)

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping Ubiquitin-Like Modifier Activating Enzyme 7 Antibodies (83) and Ubiquitin-Like Modifier Activating Enzyme 7 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UBA7 74153  
UBA7 301000  
UBA7 7318 P41226
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Top Ubiquitin-Like Modifier Activating Enzyme 7 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$686.40
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

UBA7 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , , ,
,

More Proteins for Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) Interaction Partners

Mouse (Murine) Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) interaction partners

  1. Bone marrow transplantation experiment revealed a 50% reduction in repopulation potential of Ube1L-deficient cells at 3weeks posttransplantation, but no differences at 6 and 12weeks.

  2. UBE1L and protein ISGylation are not critical for IFN-alpha (show IFNA Proteins)/beta signaling via JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins) activation.

  3. Ube1l is not a tumor suppressor gene in K-ras(LA2) lung cancer mouse model.

  4. Both UbE1L(-/-) and ISG15 (show ISG15 Proteins)(-/-) mice display increased susceptibility to influenza B virus infection, including non-mouse-adapted strains.

  5. The importance of UbE1L was confirmed by demonstrating that mice lacking this ISG15 (show ISG15 Proteins) E1 enzyme (show ENOPH1 Proteins) were highly susceptible to Sindbis virus infection.

Human Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) interaction partners

  1. the cellular effects of progerin expression in Hutchinson-Gilford progeria syndrome are transduced, at least in part, through reduced function of the Ran GTPase (show RAN Proteins) and E2 SUMOylation pathways.

  2. UBE1L is a retinoid target that triggers PML (show PML Proteins)/RARalpha (show RARA Proteins) degradation and apoptosis in acute promyelocytic leukemia (show PML Proteins)

  3. RA treatment of APL (show FASL Proteins) and other RA-responsive leukemic cells induced expression of UBE1L and ISG15 (show ISG15 Proteins) as well as intracellular ISG15 (show ISG15 Proteins) conjugates. A physical association was found between UBE1L and ISG15 (show ISG15 Proteins) in vivo.

  4. Ube1L was required for transfer of ISG15 (show ISG15 Proteins) to UbcH8 (show UBE2E2 Proteins) and for binding of Ube1L to UbcH8 (show UBE2E2 Proteins)

  5. UBE1L-ISG15 (show ISG15 Proteins) preferentially inhibits cyclin D1 (show CCND1 Proteins) in lung cancer

Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) Protein Profile

Protein Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.

Gene names and symbols associated with UBA7

  • ubiquitin-like modifier activating enzyme 7 (Uba7)
  • ubiquitin-like modifier activating enzyme 7 (UBA7)
  • ubiquitin-like modifier activating enzyme 6 (UBA6)
  • ubiquitin-activating enzyme E1-like (LOC567370)
  • ubiquitin-conjugating enzyme E2R 2 (ube2r2)
  • 1300004C08Rik protein
  • D8 protein
  • UBA1B protein
  • UBE1 protein
  • UBE1L protein
  • UBE1L2 protein
  • UBE2 protein
  • xubc3 protein

Protein level used designations for UBA7

ubiquitin-like modifier-activating enzyme 7 , ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing) , ubiquitin-activating enzyme E1-like 2 , ubiquitin-activating enzyme E1-like , ubiquitin-like modifier activating enzyme 7 , ubiquitin-like modifier-activating enzyme 7-like , ubiquitin-conjugating enzyme E2R 2 , ubiquitin conjugating enzyme E2 , UBA1, ubiquitin-activating enzyme E1 homolog B , UBA7, ubiquitin-activating enzyme E1 , ubiquitin-activating enzyme 7 , ubiquitin-activating enzyme E1 homolog , ubiquitin-activating enzyme E1-related protein , ubiquitin-activating enzyme-2

GENE ID SPECIES
74153 Mus musculus
301000 Rattus norvegicus
395178 Gallus gallus
461294 Pan troglodytes
497204 Bos taurus
567370 Danio rerio
608118 Canis lupus familiaris
744322 Pan troglodytes
704875 Macaca mulatta
100028084 Monodelphis domestica
100052809 Equus caballus
100092397 Ornithorhynchus anatinus
100338238 Oryctolagus cuniculus
100399374 Callithrix jacchus
100446669 Pongo abelii
100482099 Ailuropoda melanoleuca
100512631 Sus scrofa
779010 Xenopus laevis
7318 Homo sapiens
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