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VPS29 belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. Additionally we are shipping Vacuolar Protein Sorting 29 Homolog (S. Cerevisiae) Proteins (19) and many more products for this protein.
Showing 10 out of 51 products:
Human Polyclonal VPS29 Primary Antibody for ELISA, WB - ABIN565652
Miura, Hasegawa, Konno, Suzuki, Sugeno, Fujikake, Geisler, Tabuchi, Oshima, Kikuchi, Baba, Wada, Nagai, Takeda, Aoki: VPS35 dysfunction impairs lysosomal degradation of ?-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease. in Neurobiology of disease 2014
Human Polyclonal VPS29 Primary Antibody for ICC, IF - ABIN4365830
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Human Polyclonal VPS29 Primary Antibody for ELISA, WB - ABIN250157
Haft, de la Luz Sierra, Bafford, Lesniak, Barr, Taylor: Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes. in Molecular biology of the cell 2000
Human Polyclonal VPS29 Primary Antibody for IHC (p), IHC - ABIN251587
Nakada-Tsukui, Saito-Nakano, Ali, Nozaki: A retromerlike complex is a novel Rab7 effector that is involved in the transport of the virulence factor cysteine protease in the enteric protozoan parasite Entamoeba histolytica. in Molecular biology of the cell 2005
The retromer complex is a highly conserved membrane trafficking assembly composed of three proteins - Vps26 (show VPS26A Antibodies), Vps29 and Vps35 (show vps35 Antibodies), which are impaired in neurodegenerative diseases. (Review)
Heterotrimer composed of DSCR3 (show DSCR3 Antibodies), C16orf62 and VPS29 orchestrates endosomal cargo retrieval and recycling.
This study demonstrated that Genetic variability of VPS29 in parkinsonism.
Data indicate that vesicular transport proteins VPS35 (show vps35 Antibodies) and VPS29 influence the levels of the other subunit of retromer.
Conclusion is that VPS29 is a metal ion-independent, rigid scaffolding domain, which is essential but not sufficient for incorporation of retromer into functional endosomal transport assemblies.
analysis of the phosphodiesterase/nuclease (show DCLRE1C Antibodies)-like fold and two protein-protein interaction sites in human VPS29
It was demonstrated that recombinant human Vps29 displays in vitro phosphatase activity towards a serine-phosphorylated peptide, containing the acidic-cluster dileucine motif of the cytoplasmatic tail of the CI-M6PR (show IGF2R Antibodies).
These observations indicate that the mammalian retromer complex assembles by sequential association of SNX1 (show SNX1 Antibodies)/2 and Vps26 (show VPS26A Antibodies)-Vps29-Vps35 (show vps35 Antibodies) subcomplexes on endosomal membranes and that SNX1 (show SNX1 Antibodies) and SNX2 (show SNX2 Antibodies) play interchangeable but essential roles.
crystal structure of a VPS29-VPS35 (show vps35 Antibodies) subcomplex showing how the metallophosphoesterase-fold subunit VPS29 acts as a scaffold for the carboxy-terminal half of VPS35 (show vps35 Antibodies)
Membrane recruitment of the cargo-selective retromer subcomplex VPS35 (show vps35 Antibodies)/29/26 is catalysed by the small GTPase (show RACGAP1 Antibodies) Rab7 (show RAB7B Antibodies) and inhibited by the Rab (show HRB Antibodies)-GAP TBC1D5 (show TBC1D5 Antibodies).
These results suggest that mouse Vps26b (show VPS26B Antibodies)-Vps29-Vps35 (show vps35 Antibodies) retromer complex is implicated in the transport of sortilin (show SORT1 Antibodies) from endosomes to the trans-Golgi network.
Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly.
VPS29 plays a crucial role in recycling VSRs from the PVC to the trans-Golgi network during the trafficking of soluble proteins to the lytic vacuole .
A combination of immunoelectron and fluorescence microscopy show that VPS29p localize to the trans-Golgi network (TGN (show TG Antibodies)), which is considered to represent the early endosome of plants.
Findings suggest that MAG1/VPS29 protein is involved in recycling a plant receptor for the efficient sorting of seed storage proteins
VPS29 is required for endosome homeostasis, PIN (show DYNLL1 Antibodies) protein cycling, and dynamic PIN1 repolarization during plant organ development.
This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms, and usage of multiple polyadenylation sites have been found for this gene.
, retromer protein
, vacuolar protein sorting-associated protein 29
, vacuolar sorting protein VPS29/PEP11
, vesicle protein sorting 29
, x 007 protein
, vacuolar sorting protein 29
, Vesicle protein sorting 29
, vacuolar protein sorting 29 homolog
, Vacuolar protein sorting-associated protein 29
, vacuolar protein sorting 29 homolog (S. cerevisiae)
, hypothetical protein
, protein involved in endosome to golgi protein transport
, subunit of retromer complex
, vacuolar protein sorting 29