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The protein encoded by VCY is a member of a family of human VCX/Y genes.
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Identified members of the VCX/Y gene family as novel CT antigens.
Human VCX/Y, SPANX, and CSAG2 gene families together with the murine SPANX gene and the CYPT family may share a common ancestor.
The protein encoded by this gene is a member of a family of human VCX/Y genes. This gene family has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. Members of the VCX/Y family share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. VCX/Y genes encode small and highly charged proteins of unknown function. This gene encodes a small, positively charged protein. The presence of a putative bipartite nuclear localization signal suggests that this gene encodes a nuclear protein. The genome has two identical copies of this gene within a palindromic region\; this record represents the more centromeric copy.
basic charge, Y-linked 1
, basic protein on Y chromosome, 1
, testis-specific basic protein Y 1
, testis-specific basic protein on Y, 1
, variable charge, Y chromosome
, variably charged protein Y