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VDAC3 encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. Additionally we are shipping and many more products for this protein.
Showing 10 out of 45 products:
Cow (Bovine) Polyclonal VDAC3 Primary Antibody for IHC, WB - ABIN2776182
Lefièvre, Chen, Conner, Scott, Publicover, Ford, Barratt: Human spermatozoa contain multiple targets for protein S-nitrosylation: an alternative mechanism of the modulation of sperm function by nitric oxide? in Proteomics 2007
Show all 4 Pubmed References
Human Polyclonal VDAC3 Primary Antibody for WB - ABIN4894329
Tanno, Kuno, Ishikawa, Miki, Kouzu, Yano, Murase, Tobisawa, Ogasawara, Horio, Miura: Translocation of glycogen synthase kinase-3β (GSK-3β), a trigger of permeability transition, is kinase activity-dependent and mediated by interaction with voltage-dependent anion channel 2 (VDAC2). in The Journal of biological chemistry 2014
This cohort study showed that the VDAC3 gene was down regulation between patients with idiopathic Parkinson disease and controls
The works available on VDAC cysteines support the notion that VDAC1 (show VDAC1 Antibodies), VDAC2 (show VDAC2 Antibodies), and VDAC3 proteins are paralogs with a similar pore-function and slightly different, but important, ancillary biological functions. (Review)
VDAC3 is able to modulate its pore size and current by exploiting the mobility of the N-terminal and forming, upon external stimuli, disulfide bridges with cysteine residues located on the barrel and exposed to the inter-membrane space.
channel gating of VDAC3 might be controlled by redox sensing under physiological conditions
These data suggest that an interaction between Mcl-1 (show MCL1 Antibodies) and VDAC promotes lung cancer cell migration by a mechanism that involves Ca(2 (show CA2 Antibodies)+)-dependent reactive oxygen species production.
observed electrophysiological properties of hVDAC3 are surprisingly different from the other isoforms and are discussed in relation to the proposed physiological role of the protein in mammalian cells
a VDAC3-Mps1 (show IDUA Antibodies) module at the centrosome promotes ciliary disassembly during cell cycle entry.
VDAC3 is present at the mother centriole and modulates centriole assembly by recruiting Mps1 (show IDUA Antibodies) to centrosomes.
VDAC 1 (show VDAC1 Antibodies), 2, and 3 recruit Parkin (show PARK2 Antibodies) to defective mitochondria to promote mitochondrial autophagy.
VDAC3 has a limited ability to support mitochondrial respiration and has no influence in the control of ROS (show ROS1 Antibodies) production.
VDAC2 (show VDAC2 Antibodies) and VDAC3 might have an alternative structural organization and different functions in outer dense fibers (show ODF1 Antibodies) than in mitochondria
Bcl-xL (show BCL2L1 Antibodies) interacts functionally with VDAC1 (show VDAC1 Antibodies) and -3 but not VDAC2 (show VDAC2 Antibodies).
(n VDAC3 deficient mice the defect is restricted to the heart and only to complex IV.
Vdacs are dispensable for both MPT and Bcl-2 (show BCL2 Antibodies) family member-driven cell death.
Bid (show BID Antibodies) catalyzes MAC formation in isolated mitochondria containing Bax (show BAX Antibodies) and/or Bak (show BAK1 Antibodies) with a time course of minutes and does not require VDAC1 (show VDAC1 Antibodies) or VDAC3.
This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene.
, voltage-dependent anion channel 3
, voltage-dependent anion channel 5, pseudogene
, voltage-dependent anion-selective channel protein 3
, voltage-dependent anion channel 1 pseudogene 5
, outer mitochondrial membrane protein porin 3
, channel protein VDAC3
, mitochondrial outer membrane protein
, mitochondrial voltage dependent anion channel 3