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ZNF274 encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. Additionally we are shipping Zinc Finger Protein 274 Proteins (4) and many more products for this protein.
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Human Polyclonal ZNF274 Primary Antibody for WB - ABIN1882019
Casademunt, Carter, Benzel, Frade, Dechant, Barde: The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death. in The EMBO journal 2000
Show all 5 Pubmed References
Human Polyclonal ZNF274 Primary Antibody for ELISA, WB - ABIN564699
Frietze, OGeen, Blahnik, Jin, Farnham: ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes. in PLoS ONE 2010
A proximal promoter construct for the MAS (show MAS1 Antibodies) gene was repressed by the SOX (show PIPOX Antibodies) [SRY (show SRY Antibodies) (sex-determining region on the Y chromosome) box] proteins SRY (show SRY Antibodies), SOX2 (show SOX2 Antibodies), SOX3 (show SOX3 Antibodies) and SOX14 (show SOX14 Antibodies), of which SRY (show SRY Antibodies) is known to interact with the KRAB domain.
analysis of a KRAB domain-containing ZNF (show ZNF629 Antibodies) (ZNF274) that is involved in recruitment of the KAP1 (show CDKN3 Antibodies) and SETDB1 (show SETDB1 Antibodies) to specific regions of the human genome
KAP1 (show CDKN3 Antibodies) functions to coordinate activities that dynamically regulate changes in histone modifications and deposition of HP1 (show DEFA1 Antibodies) to establish a de novo microenvironment of heterochromatin, which is required for repression of gene transcription by KRAB-zfps.
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals.
zinc finger protein 274
, KRAB zinc finger protein HFB101
, neurotrophin receptor-interacting factor homolog
, zinc finger protein HFB101
, zinc finger protein with KRAB and SCAN domains 19
, zinc finger protein zfp2