anti-clathrin, Heavy Chain (Hc) (CLTC) Antibodies

Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLTC 1213 Q00610
CLTC 67300 Q68FD5
CLTC 54241 P11442
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Top anti-clathrin, Heavy Chain (Hc) Antibodies at antibodies-online.com

Showing 10 out of 146 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Mouse Un-conjugated EIA, FACS, IF, IP, WB 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Cow Mouse Un-conjugated ICC, FACS, IF, IM, IHC (p), IP, IHC, WB Flow Cytometry: Clathrin Heavy Chain 1/CHC17 Antibody (X22) [ABIN152766] - Analysis of Alexa Fluor (R) 488 conjugate of ABIN152766. A cell surface stain was performed on HeLa cells with Clathrin Heavy Chain 1 antibody ABIN152766AF488 (blue) along with a matched isotype control NBP2-27287AF488 (orange). Cells were incubated in an a Western Blot: Clathrin Heavy Chain 1/CHC17 Antibody (X22) [ABIN152766] - Analysis of 25 ug of human brain lysates. 0.1 mL Log in to see 7 to 9 Days
$408.19
Details
Cow Mouse Un-conjugated WB Western Blot: Clathrin heavy chain Antibody (TD.1) [ABIN2658781] - Cell line lysates were separated on SDS-PAGE and probed with 4 ug/mL Monoclonal Anti-Clathrin Heavy Chain Clone: TD.1. The antibody was developed using Goat Anti-Mouse IgG-Peroxidase and a chemiluminescent substrate. Lanes 1. HEK-293T 2. HeLa 3. SH-SY5Y 4. SK-N-SH 5. COS7 6. PC12 7. Neuro-2a 0.1 mL Log in to see 7 to 9 Days
$408.19
Details
Arabidopsis thaliana Rabbit Un-conjugated IF, IL, WB 100 μg Log in to see 6 to 8 Days
$497.81
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB CLTC Antibody (Center) (ABIN652092) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the CLTC antibody detected the CLTC protein (arrow). CLTC antibody (Center) (ABIN652092) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Bat Goat Un-conjugated IHC (p) Adrenal, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Kidney, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of Clathrin Heavy Chain staining in rat kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incuba Western blot analysis of Clathrin Heavy Chain expression in Hela (A), MCF7 (B), mouse lung (C), rat brain (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Amphibian Mouse Un-conjugated IHC (fro), WB   0.1 mg Log in to see 6 to 8 Days
$346.50
Details
Bat Goat Un-conjugated IHC (p) Immunohistochemistry-Paraffin: Clathrin Heavy Chain 1/CHC17 Antibody [NBP1-52529] - Analysis of anti-CLTC antibody with human kidney at concentration 3.75 ug/ml. Immunohistochemistry-Paraffin: Clathrin Heavy Chain 1/CHC17 Antibody [NBP1-52529] - Analysis of anti-CLTC antibody with human adrenal at concentration 3.75 ug/ml. 0.05 mg Log in to see 10 to 13 Days
$500.06
Details

CLTC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-clathrin, Heavy Chain (Hc) Antibodies

  1. Cow (Bovine) Monoclonal CLTC Primary Antibody for ICC, FACS - ABIN152766 : Fernandez, McVicker, Tuma, Tuma: Ethanol selectively impairs clathrin-mediated internalization in polarized hepatic cells. in Biochemical pharmacology 2009 (PubMed)
    Show all 6 Pubmed References

  2. Cow (Bovine) Monoclonal CLTC Primary Antibody for WB - ABIN265878 : Grossman, Ebke, Beight, Jang, Crabb, Hagstrom: Protein partners of dynamin-1 in the retina. in Visual neuroscience 2013 (PubMed)

  3. Human Polyclonal CLTC Primary Antibody for IF (p) - ABIN891159 : Kuhn, Vanhecke, Michen, Blank, Gehr, Petri-Fink, Rothen-Rutishauser: Different endocytotic uptake mechanisms for nanoparticles in epithelial cells and macrophages. in Beilstein journal of nanotechnology 2014 (PubMed)

More Antibodies against clathrin, Heavy Chain (Hc) Interaction Partners

Caenorhabditis elegans (C. elegans) clathrin, Heavy Chain (Hc) (CLTC) interaction partners

  1. The clathrin heavy chain CHC-1 negatively regulates pulling forces acting on centrosomes during interphase and on spindle poles during mitosis in one-cell C. elegans embryos.

  2. Inactivating epn-1 (show EPN1 Antibodies) or chc-1 disrupts engulfment by impairing actin polymerization. CHC-1 is enriched on extending pseudopods together with EPN-1 (show EPN1 Antibodies), in an EPN-1 (show EPN1 Antibodies)-dependent manner.

  3. These results indicate that a high level of CHC activity is required for receptor-mediated endocytosis in nonneuronal cells but is largely dispensable for maintenance of synaptic vesicle pools.

  4. Loss of SNX-1 (show SNX1 Antibodies), RME-8, or the clathrin chaperone Hsc70 (show HSPA8 Antibodies)/HSP-1 leads to over-accumulation of endosomal clathrin, reduced clathrin dynamics, and missorting of MIG-14 (show RAE1 Antibodies) to the lysosome.

Arabidopsis thaliana clathrin, Heavy Chain (Hc) (CLTC) interaction partners

  1. Data indicate that MTV1 (AT3G16270) and AGD5 (AT5G54310) Physically Interact with clathrin.

  2. study presents a genetic characterization of the role of clathrin in endocytosis and auxin-mediated plant development; data demonstrate a fundamental role for clathrin function in cell polarity, growth, patterning, and organogenesis

Pig (Porcine) clathrin, Heavy Chain (Hc) (CLTC) interaction partners

  1. Taken together, these results demonstrate that Japanese encephalitis virus enters porcine kidney epithelial PK15 cells through cholesterol- and clathrin-mediated endocytosis.

  2. Clathrin plays a crucial role in meiotic spindle function in maturing oocytes, possibly through spindle stabilization

Human clathrin, Heavy Chain (Hc) (CLTC) interaction partners

  1. this study shows that clathrin, including the clathrin population associated to internal vesicles, controls lymphocyte migration by regulating actin rearrangements occurring at the leading age

  2. The novel association of several endocytosis-associated proteins has been demonstrated, in particular, of CLTC and SCAMP3 (show SCAMP3 Antibodies) with hepatocellular carcinoma progression.

  3. MiR (show MLXIP Antibodies)-199a-5p suppresses tumorigenesis by targeting CLTC in hepatocellular carcinoma.

  4. Data indicate that clathrin-mediated endocytosis of proto-oncogene (show RAB1A Antibodies) protein erbB-3 (ErbB3 (show ERBB3 Antibodies)) is depending on epsin-1 (show EPN1 Antibodies).

  5. SMAP2 (show BRD8 Antibodies) immunoprecipitated clathrin and AP-1 (show FOSB Antibodies) through a putative clathrin-binding domain and a CALM-binding domain, and SMAP2 (show BRD8 Antibodies) mutants that did not interact with clathrin or AP-1 (show FOSB Antibodies) could not localize to recycling endosomes

  6. autophagy contributed to Cx31.1 (show GJB5 Antibodies) degradation, and clathrin might be involved in the autophagy of Cx31.1 (show GJB5 Antibodies).

  7. Data suggest that by binding to both clathrin and F-actin, mammalian actin-binding protein 1 (mAbp1 (show DBNL Antibodies); HIP-55 (show DBNL Antibodies) or SH3P7 (show DBNL Antibodies)) is specifically recruited at a late stage of clathrin-coated pits (CCPs) formation, which subsequently recruits dynamin (show DNM1 Antibodies) to CCPs.

  8. In conclusion these data suggest that Streptococcus pneumoniae PspC-promoted uptake via the polymeric immunoglobulin receptor of epithelial cells is mediated by both clathrin and caveolin dependent pathway.

  9. Our data support a model in which nascent Hepatits C Virus particles associate with apoE in the endoplasmic reticulum and exit cells following a clathrin-dependent transendosomal secretory route.

  10. clathrin-mediated and caveolae-mediated endocytosis of VE-cad (show CDH5 Antibodies) contribute to lipopolysaccharide-induced vascular hyperpermeability.

Cow (Bovine) clathrin, Heavy Chain (Hc) (CLTC) interaction partners

  1. three different clathrin-box motif peptides can each simultaneously bind not only to the previously characterized clathrin-box site but also to the W-box site and the beta-arrestin splice loop site on a single TD.

  2. Structure of clathrin coat with bound Hsc70 (show HSPA8 Antibodies) and auxilin (show DNAJC6 Antibodies).

  3. clathrin-FKBP36-Hsp72 complexes resulting from both identified interactions are bound to the matrices of clathrin-coated vesicles in spermatocytes, which indicates a possible role of FKBP36 and Hsp72 in the disassembly of clathrin coats

Mouse (Murine) clathrin, Heavy Chain (Hc) (CLTC) interaction partners

  1. our results demonstrate that CKAP5 (show CKAP5 Antibodies) is important in oocyte maturation and early embryo development, and CKAP5 (show CKAP5 Antibodies) might work together with CLTC in mouse oocyte maturation

  2. SP-A (show SFTPA1 Antibodies) transiently enhances the basal protein expression of CHC and alpha-adaptin (show AP2A2 Antibodies).

  3. MiR (show MLXIP Antibodies)-199a-5p suppresses tumorigenesis by targeting CLTC in hepatocellular carcinoma.

  4. PTEN-like domains of GAK and auxilin are not essential for Hsc70-dependent chaperoning and uncoating of clathrin, but depending on the tissue, these domains appear to increase the efficiency of these co-chaperones.

  5. The clathrin-mediated endocytic machinery combines with Dab2 (show DAB2 Antibodies) to facilitate the endocytosis of RGD-integrin-beta3 clusters.

  6. Taken together, these results show that CLTC plays an important role in spindle assembly and chromosome congression through a microtubule correlation mechanism during mouse oocyte maturation.

  7. Auditory inner hair cells use dynamin-dependent endocytosis via clathrin-mediated endocytosis.

  8. Data indicate that dynamin (show DNM1 Antibodies), clathrin, adaptor protein complex-2 (AP2 (show TFAP2A Antibodies)), and amphiphysin (show AMPH Antibodies) contribute to the depolarization-evoked entry in endocytosis.

  9. This study reveals a novel functional role of clathrin-coated structure in GMR (show CSF2RA Antibodies) signaling and the oncogenesis of JAK2V617F.

  10. The authors report that Dab2, previously described as an inhibitor of Wnt/beta-catenin signalling, selectively recruits LRP6 to the clathrin-dependent endocytic route, thereby sequestering it from caveolin-mediated endocytosis.

clathrin, Heavy Chain (Hc) (CLTC) Antigen Profile

Protein Summary

Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains.

Gene names and symbols associated with CLTC

  • clathrin heavy chain (CHC1) antibody
  • Probable clathrin heavy chain 1 (chc-1) antibody
  • clathrin heavy chain (CLTC) antibody
  • clathrin heavy chain (Chc) antibody
  • clathrin heavy chain (TP03_0480) antibody
  • clathrin heavy chain (LOC5578293) antibody
  • putative clathrin heavy chain (LMJF_36_1630) antibody
  • clathrin heavy chain (CpipJ_CPIJ014882) antibody
  • clathrin heavy chain 1 (CNJ03270) antibody
  • clathrin heavy chain 1 (ATEG_05434) antibody
  • clathrin heavy chain 1 (CMU_025200) antibody
  • clathrin heavy chain (PMAA_094250) antibody
  • clathrin heavy chain Chc1 (SJAG_02282) antibody
  • clathrin heavy chain (Smp_154420.1) antibody
  • clathrin heavy chain 1 (PAAG_00730) antibody
  • clathrin heavy chain (MCYG_06136) antibody
  • clathrin heavy chain 1 (VDBG_05048) antibody
  • clathrin heavy chain 1 (MGYG_04658) antibody
  • clathrin heavy chain (cgd8_1270) antibody
  • clathrin heavy chain (Tc00.1047053506167.50) antibody
  • clathrin heavy chain (CHC) antibody
  • clathrin, heavy polypeptide (Hc) (Cltc) antibody
  • clathrin heavy chain (Cltc) antibody
  • Clathrin, heavy chain (AT3G11130) antibody
  • clathrin, heavy chain (Hc) L homeolog (cltc.L) antibody
  • 3110065L21Rik antibody
  • Chc antibody
  • CHC17 antibody
  • CLH-17 antibody
  • cltc antibody
  • CLTCL2 antibody
  • F11B9.30 antibody
  • Hc antibody
  • R74732 antibody

Protein level used designations for CLTC

clathrin heavy chain , Clathrin Heavy Chain family member (chc-1) , clathrin heavy chain 1 , clathrin heavy-chain , clathrin, heavy polypeptide (Hc) , clathrin heavy chain on chromosome 17 , clathrin, heavy polypeptide-like 2 , clathrin, heavy chain (Hc) , clathrin, heavy chain (Hc) L homeolog

GENE ID SPECIES
5725357 Chlamydomonas reinhardtii
176434 Caenorhabditis elegans
395272 Gallus gallus
100271929 Sus scrofa
100233163 Bombyx mori
1213 Homo sapiens
3499985 Theileria parva strain Muguga
5578293 Aedes aegypti
5655418 Leishmania major strain Friedlin
6047964 Culex quinquefasciatus
281080 Bos taurus
455168 Pan troglodytes
3254223 Cryptococcus neoformans var. neoformans JEC21
4320947 Aspergillus terreus NIH2624
6995013 Cryptosporidium muris RN66
7026543 Talaromyces marneffei ATCC 18224
7049029 Schizosaccharomyces japonicus yFS275
8340532 Schistosoma mansoni
9100448 Paracoccidioides sp. 'lutzii' Pb01
9227238 Arthroderma otae CBS 113480
9532124 Verticillium alfalfae VaMs.102
10027332 Arthroderma gypseum CBS 118893
100228172 Taeniopygia guttata
480578 Canis lupus familiaris
3374266 Cryptosporidium parvum Iowa II
3540437 Trypanosoma cruzi strain CL Brener
7449343 Thalassiosira pseudonana CCMP1335
67300 Mus musculus
54241 Rattus norvegicus
820284 Arabidopsis thaliana
444287 Xenopus laevis
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