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The enzyme encoded by GGT1 catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. Additionally we are shipping gamma Glutamyltransferase 1 Kits (43) and gamma Glutamyltransferase 1 Proteins (17) and many more products for this protein.
Showing 10 out of 131 products:
Human Polyclonal GGT1 Primary Antibody for WB - ABIN1881373
Ikeda, Maki, Yin, Kawate, Adachi, Ohnaka, Takayanagi, Kono: Relation of coffee consumption and serum liver enzymes in Japanese men and women with reference to effect modification of alcohol use and body mass index. in Scandinavian journal of clinical and laboratory investigation 2010
Show all 4 references for ABIN1881373
Human Monoclonal GGT1 Primary Antibody for IHC (p), IP - ABIN561038
West, Segu, Feasley, Kang, Klouckova, Li, Novotny, West, Mechref, Hanigan: Analysis of site-specific glycosylation of renal and hepatic ?-glutamyl transpeptidase from normal human tissue. in The Journal of biological chemistry 2010
Show all 4 references for ABIN561038
Mouse (Murine) Polyclonal GGT1 Primary Antibody for WB - ABIN1881372
Aly, Lightfoot, El-Shemy: Modulatory role of lipoic acid on lipopolysaccharide-induced oxidative stress in adult rat Sertoli cells in vitro. in Chemico-biological interactions 2009
Show all 3 references for ABIN1881372
Human Monoclonal GGT1 Primary Antibody for FACS, IHC (fro) - ABIN180610
Knoll, Wrasidlo, Scherberich, Gaedicke, Fischer: Targeted therapy of experimental renal cell carcinoma with a novel conjugate of monoclonal antibody 138H11 and calicheamicin thetaI1. in Cancer research 2000
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In patients with coronary artery disease, elevated gamma-glutamyltransferase activity is independently associated with the presence of atrial fibrillation.
Specific gene polymorphisms are known to be associated with a different arterial physiology in the younger generation. The present study found that young Russians with the matrix metalloproteinase 3 6A/6A and gamma-glutamyltransferase 1AA genotypes have lower levels of the cardio-ankle vascular index - a recent measure of arterial stiffness.
Preoperative GGT can serve as an independent prognostic biomarker of nonmetastatic renal cell carcinoma (show MOK Antibodies) patients with venous tumor thrombus.
he cardiovascular risk, evaluated with Framingham risk scoring system, increased among fatty liver disease patients compared with control group. Another major finding of this study was the association of higher GGT levels with the increased cardiovascular disease risk.
As a biomarker of GSH status, GGT has several technical advantages such as low cost, easy sample preparation, stability in previously thawed samples and ready availability of clinical laboratory measurement techniques  . However, the limitations of GGT as a novel marker of cardiovascular health need to be acknowledged.
We demonstrated a significant correlation between serum GGT levels and VBI. In addition, higher GGT level was an independent risk factor for the presence of vertebrobasilar system inflammation and atherosclerosis
We conclude that Increased serum GGT levels are associated with some markers of ventricular repolarization abnormalities in the early stage of type 2 diabetes
gamma-glutamyltransferase is present in atherosclerotic lesions in the coronary and carotid arteries, and has a prooxidant role leading to the production of reactive oxygen species and atherosclerosis
Elevated serum GGT levels are independently associated with coronary artery calcification progression
gamma-Glutamyltransferase is an independent risk factor for breast cancer beyond the consumption of alcohol and other life style risk factors
Statins can significantly decrease the expression of GGT in aortic atherosclerotic plaques of ApoE (show APOE Antibodies)-knockout mice.
Gamma-glutamyltransferase levels are an independent predictor of worsening kidney function and mortality in acute heart failure patients.
Disruption of the Mrds1/Ofcc1 gene elicits asymptomatic hyper-gamma-glutamyl-transpeptidasemia in mice.
Mutations in the Ggt1 gene are responsible for the phenotypes of dwg/dwg and dwg(Bayer)/dwg(Bayer) mice.
prooxidant reactions mediated by gamma-GT in turn regulate the levels of tyrosinase (show TYR Antibodies) in pigment cells.
GGT regulates osteoclast biology at least partly independently of sex steroids
GGT stimulates RANKL (show TNFSF11 Antibodies) expression
GGT is implicated as being involved in diseases characterized by accelerated osteoclast development and bone destruction.
This gene encodes a member of the gamma-glutamyl transpeptidase (GGT) family, which are important in the metabolism of glutathione. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. In contrast, the product of this gene only contains homology to the light chain region, and lacks a transmembrane domain. Multiple alternatively spliced variants, encoding the same protein, have been identified.
, gamma-glutamyltranspeptidase 1
, gamma-glutamyl transpeptidase
, ggt 1
, gamma-glutamyltransferase 1 a
, Gamma-glutamyltranspeptidase 1
, gamma-glutamyltranspeptidase 1-like
, glutamyl transpeptidase
, glutathione hydrolase 1
, leukotriene-C4 hydrolase
, GGT 1
, gamma glutamyl-transferase 1
, gamma-glutamyltransferase 2
, gamma-glutamyltransferase-like activity 3
, gamma-glutamyltransferase-like activity 4
, gamma-glutamyltransferase-like protein 6