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phosphorylase Kinase, alpha 1 (Muscle) Proteins (PHKA1)

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. Additionally we are shipping PHKA1 Antibodies (12) and PHKA1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PHKA1 18679 P18826
Rat PHKA1 PHKA1 64561 Q64649
PHKA1 5255 P46020
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Top PHKA1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PHKA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for phosphorylase Kinase, alpha 1 (Muscle) (PHKA1) Interaction Partners

Rabbit phosphorylase Kinase, alpha 1 (Muscle) (PHKA1) interaction partners

  1. The investigation is concerned with the effects of arginine on protein-protein interactions using phosphorylase kinase (PhK (show PHKA2 Proteins)) as an example.

Human phosphorylase Kinase, alpha 1 (Muscle) (PHKA1) interaction partners

  1. muscle PHKA deficiency may present as an almost asymptomatic condition, despite a mild impairment of muscle

  2. alpha- and beta-subunits possess amino-terminal glucoamylase-like domains and suggests that they might possess a previously overlooked amylase (show AMY Proteins) activity

  3. X-linked PHK (show PHKA2 Proteins) deficiency causes a mild metabolic myopathy with blunted muscle glycogen (show GYS1 Proteins) breakdown and impaired lactate production during dynamic exercise, which impairs oxidative capacity only marginally

PHKA1 Protein Profile

Protein Summary

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9D, also known as X-linked muscle glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. A pseudogene has been found on chromosome 1.

Gene names and symbols associated with PHKA1

  • phosphorylase kinase, alpha 1 (muscle) (PHKA1)
  • phosphorylase kinase, alpha 1 (muscle) (phka1)
  • phosphorylase kinase alpha 1 (Phka1)
  • phosphorylase kinase alpha subunit (LOC100303771)
  • phosphorylase kinase, alpha 1 (Phka1)
  • 5330411D17 protein
  • 9830108K24Rik protein
  • Pcyt1b protein
  • PHKA protein
  • PHKA1 protein
  • wu:fl37h01 protein

Protein level used designations for PHKA1

phosphorylase kinase, alpha 1 (muscle) , phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform , phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform-like , phosphorylase kinase alpha M subunit , Phosphorylase kinase alpha M subunit , PhK-alpha-subunit , phosphorylase B kinase alpha subunit , phosphorylase kinase alpha-subunit , phosphorylase b kinase regulatory subunit alpha skeletal muscle isoform , phosphorylase kinase, alpha 1 (muscle), muscle glycogenosis

GENE ID SPECIES
422181 Gallus gallus
465713 Pan troglodytes
572183 Danio rerio
699764 Macaca mulatta
100051524 Equus caballus
100158624 Xenopus (Silurana) tropicalis
100396892 Callithrix jacchus
100435132 Pongo abelii
100479757 Ailuropoda melanoleuca
100587383 Nomascus leucogenys
18679 Mus musculus
100303771 Oryctolagus cuniculus
64561 Rattus norvegicus
5255 Homo sapiens
491956 Canis lupus familiaris
525990 Bos taurus
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