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rho GTPase Activating Protein 24 Proteins (ARHGAP24)

ARHGAPs, such as ARHGAP24, encode negative regulators of Rho GTPases (see ARHA\; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).[supplied by OMIM, Mar 2008].. Additionally we are shipping ARHGAP24 Antibodies (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ARHGAP24 83478 Q8N264
ARHGAP24 231532 Q8C4V1
Rat ARHGAP24 ARHGAP24 305156 Q5U2Z7
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Top ARHGAP24 Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 69 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 69 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

ARHGAP24 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

More Proteins for rho GTPase Activating Protein 24 (ARHGAP24) Interaction Partners

Human rho GTPase Activating Protein 24 (ARHGAP24) interaction partners

  1. Src (show SRC Proteins) family tyrosine kinase (show TXK Proteins) signaling may regulate FilGAP through association with RBM10 (show RBM10 Proteins)

  2. FilGAP may contribute to change in cell motility of B-lymphocytes and in addition, its expression appears to be useful for predicting the behavior of B-cell lymphoma, in particular follicular lymphoma.

  3. study suggests that Arf6 (show ARF6 Proteins) and phosphorylation of FilGAP may regulate FilGAP, and phosphorylation of Ser (show SIGLEC1 Proteins)-402 may play a role in the regulation of cell spreading on fibronectin (show FN1 Proteins)

  4. Polymorphism rs346473 in the ARHGAP24 gene might be a part of the genetic variants.

  5. FilGAP may function as a mediator of the regulation of Rac (show AKT1 Proteins) by Arf6 (show ARF6 Proteins).

  6. Data indicate that phosphorylation of FilGAP by ROCK appears to promote amoeboid morphology.

  7. Consistent with structural predictions, strain increases beta-integrin binding to FLNA (show FLNA Proteins), whereas it causes FilGAP to dissociate from FLNA (show FLNA Proteins), providing a direct and specific molecular basis for cellular mechanotransduction

  8. sequencing of the ARHGAP24 gene in patients with focal segmental glomerulosclerosis (FSGS (show ACTN4 Proteins)) identified a mutation that impaired its Rac1-GAP activity and was associated with disease in a family with FSGS (show ACTN4 Proteins)

  9. p73 (show TP73 Proteins), a vascular cell-specific GTPase-activating protein (show RASA1 Proteins), is an important modulator of angiogenesis

  10. propose that RC-GAP72 affects cellular morphology by targeting activated Cdc42 and Rac1 GTPases to specific subcellular sites, triggering local morphological changes

Mouse (Murine) rho GTPase Activating Protein 24 (ARHGAP24) interaction partners

  1. TAp73 (show TP73 Proteins) as necessary and sufficient for basal body docking, axonemal extension, and motility during the differentiation of Motile multiciliated cell progenitors.

  2. p73 drives multiciliogenesis, both through transcriptional activation of a master ciliogenesis transcription factor FoxJ1 (show FOXJ1 Proteins) and through regulation of multiple genes central to ciliogenesis.

  3. The p73 acts as a critical regulator of multiciliogenesis in its capacity as a sequence-specific transcription factor, through genomic binding and regulation of genes.

  4. Data show that the Mdm4 (show MDM4 Proteins)-p73 axis cannot override the dominant role of p53 (show TP53 Proteins) in development and tumorigenesis and that Mdm4 (show MDM4 Proteins) and p73 interaction during development and tumorigenesis suggests new insight into the role of p53 (show TP53 Proteins) family members.

  5. In vivo inhibition of both p63 (show CKAP4 Proteins) and p73 in combination accelerates tumor regression and increases survival of p53 (show TP53 Proteins)-deficient mice.

  6. Results indicate that p73 regulates basal and starvation-induced fuel metabolism in the liver, a finding that is likely to be highly relevant for metabolism-associated disorders, such as diabetes and cancer.

  7. MDM2 (show MDM2 Proteins) mediates p73 ubiquitination

  8. p73 is required for endothelial cell differentiation, migration and the formation of vascular networks regulating VEGF (show VEGFA Proteins) and TGFbeta (show TGFB1 Proteins) signaling

  9. Although mouse TIGAR (show C12orf5 Proteins) expression is clearly induced in the intestines of mice following DNA-damaging stress of ionizing radiation, that was not dependent on p53 (show TP53 Proteins) or TAp73 (show TP73 Proteins).

  10. Ribosomal proteins L11 (show RPL11 Proteins) and L5 activate TAp73 (show TP73 Proteins) by overcoming MDM2 (show MDM2 Proteins) inhibition.

ARHGAP24 Protein Profile

Protein Summary

ARHGAPs, such as ARHGAP24, encode negative regulators of Rho GTPases (see ARHA\; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004

Gene names and symbols associated with ARHGAP24

  • Rho GTPase activating protein 24 (ARHGAP24)
  • Rho GTPase activating protein 24 (Arhgap24)
  • transformation related protein 73 (Trp73)
  • tumor protein p73 (Tp73)
  • 0610025G21Rik protein
  • FILGAP protein
  • P73 protein
  • p73RhoGAP protein
  • RC-GAP72 protein
  • RCGAP72 protein
  • Tp73 protein
  • Trp73 protein

Protein level used designations for ARHGAP24

RAC1- and CDC42-specific GTPase-activating protein of 72 kDa , filamin-A-associated RhoGAP , rho GTPase-activating protein 24 , rho-type GTPase-activating protein 24 , rhoGAP of 73 kDa , sarcoma antigen NY-SAR-88 , Down-regulated in nephrectomized rat kidney 2 , p53-like transcription factor , p53-related protein , tumor protein p73 , transformation related protein 73

100052555 Equus caballus
83478 Homo sapiens
478463 Canis lupus familiaris
100522450 Sus scrofa
539902 Bos taurus
231532 Mus musculus
305156 Rattus norvegicus
22062 Mus musculus
362675 Rattus norvegicus
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