ARHGAP24 Protein (His tag)
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- Target See all ARHGAP24 Proteins
- ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ARHGAP24 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Purified recombinant protein of Human Rho GTPase activating protein 24 (ARHGAP24), transcript variant 3, full length, with N-terminal HIS tag, expressed in E. coli, 50 μg (full length, N-term HIS tag, transcript variant 3) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- Purification
- Purified
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ARHGAP24 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
- Alternative Name
- Rho GTPase activating protein 24 (ARHGAP24 Products)
- Synonyms
- FILGAP Protein, RC-GAP72 Protein, RCGAP72 Protein, p73 Protein, p73RhoGAP Protein, 0610025G21Rik Protein, si:ch211-65i12.2 Protein, Rho GTPase activating protein 24 Protein, ARHGAP24 Protein, Arhgap24 Protein, arhgap24 Protein
- Background
- This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 73.1 kDa
- NCBI Accession
- NP_001036134
- Pathways
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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