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anti-serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) Antibodies

SHMT1 encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. Additionally we are shipping serine Hydroxymethyltransferase 1 (Soluble) Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SHMT1 287379  
SHMT1 6470 P34896
SHMT1 20425 P50431
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Top anti-serine Hydroxymethyltransferase 1 (Soluble) Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB SHMT1 Antibody (N-term) (ABIN658344) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the SHMT1 antibody detected the SHMT1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB SHMT1 monoclonal antibody (M01), clone 4F9 Western Blot analysis of SHMT1 expression in HeLa on formalin-fixed paraffin-embedded human colon tissue. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SHMT1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: A549 cell lysate  SHMT1 is supported by BioGPS gene expression data to be expressed in A549 100 μL Log in to see 2 to 3 Days
$289.00
Details
Arabidopsis thaliana Rabbit Un-conjugated WB Western Blot detection of SHMT protein in Arabidopsis thaliana leaf extract, loaded on a leaf disc area. 200 μL Log in to see 5 to 6 Days
$467.78
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to SHMT1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 1 ug/ml] Immunoperoxidase of monoclonal antibody to SHMT1 on formalin-fixed paraffin-embedded human colon tissue. [antibody concentration 1 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: U87-MG 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated IHC, ELISA, WB 0.05 mg Log in to see 2 to 3 Days
$618.75
Details
Human Rabbit FITC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

SHMT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human , ,
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Mouse (Murine)


Top referenced anti-serine Hydroxymethyltransferase 1 (Soluble) Antibodies

  1. Human Monoclonal SHMT1 Primary Antibody for WB - ABIN393802 : Porter, Basu, Hubbard, Bates, Kalman, Rey, Smith, Smith, Steinmaus, Skibola: Association of genetic variation in cystathionine-beta-synthase and arsenic metabolism. in Environmental research 2010 (PubMed)
    Show all 5 references for ABIN393802

  2. Human Polyclonal SHMT1 Primary Antibody for IHC (p), WB - ABIN658344 : Summers, Mitchell, Stanislawska-Sachadyn, Baido, Blair, Von Feldt, Whitehead: Genetic and lifestyle variables associated with homocysteine concentrations and the distribution of folate derivatives in healthy premenopausal women. in Birth defects research. Part A, Clinical and molecular teratology 2010 (PubMed)
    Show all 4 references for ABIN658344

  3. Arabidopsis thaliana Polyclonal SHMT1 Primary Antibody for WB - ABIN93560 : Wei, Sun, Sandoval, Cross, Gordon, Kang, Roje: Folate polyglutamylation eliminates dependence of activity on enzyme concentration in mitochondrial serine hydroxymethyltransferases from Arabidopsis thaliana. in Archives of biochemistry and biophysics 2013 (PubMed)
    Show all 2 references for ABIN93560

  4. Human Monoclonal SHMT1 Primary Antibody for IHC (p), ELISA - ABIN562870 : Genovese, Gualandi, Taddia, Marverti, Pirondi, Marraccini, Perco, Pelà, Guerrini, Amoroso, Esposito, Martello, Ponterini, DArca, Costi: Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides. in Journal of proteome research 2014 (PubMed)

More Antibodies against serine Hydroxymethyltransferase 1 (Soluble) Interaction Partners

Human serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) interaction partners

  1. an association between MTRR (show MTRR Antibodies) 66 and SHMT1 1420 polymorphisms and spaceflight-induced vision changes

  2. our meta-analysis suggested that the SHMT1 C1420T polymorphism was associated with decreased risk of breast cancer.

  3. SHMT1 knockdown in lung cancer cells leads to cell cycle arrest and to p53 (show TP53 Antibodies)-dependent apoptosis.

  4. In this meta-analysis, SHMT1 C1420T polymorphism did not have a significant association with the risk of cancer overall.

  5. SHMT1 exists in solution as a tetramer, both in the absence and presence of PLP (show PLP1 Antibodies), while SHMT2 (show SHMT2 Antibodies) undergoes a dimer-to-tetramer transition.

  6. found evidence for association of SHMT1 C1420T polymorphism with significantly reduced risk of breast cancer in Asians

  7. SHMT1 C1420T polymorphism is not associated with overall cancer development.

  8. serine hydroxymethyltransfarase C1420T reduces risk for both acute lymphoblastic leukemia and acute myeloid leukemia (show BCL11A Antibodies) and influences disease progression in acute lymphoblastic leukemia

  9. SHMT1 C1420T and DNMT3B (show DNMT3B Antibodies) C46359T polymorphisms are not associated with HNC (show MMP8 Antibodies) development in Brazilian population, however, SHMT1 C1420T polymorphism is less frequent in patients with primary site of tumor in larynx

  10. geography-specific effects of the SHMT1 polymorphism that render Europeans susceptible to colorectal caner, but not Americans.

Mouse (Murine) serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) interaction partners

  1. Shmt1 and dietary folate deficiency influence metabolic markers of homocysteine remethylation in mice.

  2. SHMT1 and TYMS (show TYMS Antibodies) localization to the nucleus is essential to prevent uracil accumulation in DNA

  3. Data show that Shmt1 hemizygosity was associated with increased risk for intestinal cancer in Apc (show APC Antibodies)(min)(/+) mice through a gene-by-diet interaction.

  4. These results provide evidence that disruption of Shmt1 expression causes NTDs by impairing thymidylate biosynthesis and shows that changes in the expression of genes that encode folate-dependent enzymes may be key determinates of NTD risk.

  5. Shmt1 (SHMT1), but not Srr (show SRR Antibodies), is likely to be one of the genetic components regulating prepulse inhibition in mice and possibly relevant to human schizophrenia.

  6. mitochondrial SHMT-derived one-carbon units are essential for folate-mediated one-carbon metabolism in the cytoplasm

  7. SHMT1 and SHMT2 (show SHMT2 Antibodies) are functionally redundant in nuclear de novo thymidylate biosynthesis

Rabbit serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) interaction partners

  1. we have expressed, characterized, and determined the crystal structures of rabbit cytosolic serine hydroxymethyltransferase T254A and T254C mutant forms, in the absence and presence of substrates.

Arabidopsis thaliana serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) interaction partners

  1. SHM1 and SHM2 operate in a redundant manner in one-carbon metabolism of nonphotorespiring cells with a high demand of one-carbon units.

  2. The senescence is initiated in shm1-1 under photorespiratory conditions. Transcription of the senescence marker SAG12 is enhanced in shm1-1.

  3. Structural modeling of SHM1, SHM2, and SHM4 presented features that may explain the activity differences between the mitochondrial and cytosolic isozymes.

  4. The characterization and expression of SHMT1 in A. thaliana. [SHMT1]

  5. SHM1 expression is required for mitochondrial serine hydroxymethyltransferase (show SHMT2 Antibodies) activity and proper function of the C2 cycle during growth in ambient air.

  6. SHMT1 interacts with GLU1 and this interaction is necessary for photorespiratory serine hydroxymethyltransferase (SHMT) activity.

serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) Antigen Profile

Protein Summary

This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.

Gene names and symbols associated with SHMT1

  • serine hydroxymethyltransferase 1 (soluble) (Shmt1) antibody
  • serine hydroxymethyltransferase 1 (soluble) (shmt1) antibody
  • serine hydroxymethyltransferase 1 (soluble) (SHMT1) antibody
  • serine transhydroxymethyltransferase 1 (SHM1) antibody
  • AI324848 antibody
  • AI385541 antibody
  • C81125 antibody
  • CSHMT antibody
  • F20D10.50 antibody
  • F20D10_50 antibody
  • LRRGT00032 antibody
  • MEL-32 antibody
  • MGC53442 antibody
  • mshmt antibody
  • mshmt1 antibody
  • mshmt2 antibody
  • SERINE HYDROXYMETHYLTRANSFERASE 1 antibody
  • SERINE TRANSHYDROXYMETHYLASE antibody
  • SERINE TRANSHYDROXYMETHYLTRANSFERASE antibody
  • serine transhydroxymethyltransferase 1 antibody
  • SHMT antibody
  • Shmt1 antibody
  • SHMT2 antibody
  • STM antibody
  • zgc:66171 antibody
  • zgc:77524 antibody

Protein level used designations for SHMT1

serine hydroxymethyltransferase, cytosolic , serine hydroxymethyltransferase 1 (soluble) , zSHMT-1 , SHMT , glycine hydroxymethyltransferase , serine methylase , cytoplasmic serine hydroxymethyltransferase , cytosolic serine hydroxymethyltransferase , serine hydroxymethyl transferase , serine hydroxymethyltransferase 2 (mitochondrial)

GENE ID SPECIES
287379 Rattus norvegicus
380048 Xenopus laevis
394021 Danio rerio
416520 Gallus gallus
454490 Pan troglodytes
489536 Canis lupus familiaris
548668 Xenopus (Silurana) tropicalis
100117303 Nasonia vitripennis
100159628 Acyrthosiphon pisum
100171460 Pongo abelii
100600675 Nomascus leucogenys
6470 Homo sapiens
20425 Mus musculus
100009405 Oryctolagus cuniculus
443544 Ovis aries
509002 Bos taurus
829949 Arabidopsis thaliana
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