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anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) Antibodies

There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3#-triiodothyronine (T3) in the bloodstream. Additionally we are shipping serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 Kits (48) and serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 Proteins (27) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SERPINA7 331535  
SERPINA7 6906 P05543
SERPINA7 81806 P35577
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Top anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 Antibodies at antibodies-online.com

Showing 10 out of 114 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of SERPINA7 Antibody (C-term) in MDA-MB231 cell line lysates (35ug/lane). SERPINA7 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of SERPINA7 Antibody (C-term) (ABIN390670) in MDA-MB231 cell line lysates (35 µg/lane). SERPINA7 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SERPINA7 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated WB SERPINA7 Antibody (N-term) (ABIN1881790) western blot analysis in human blood plasma tissue lysates (35 µg/lane). This demonstrates the SERPINA7 antibody detected the SERPINA7 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE antibody diluted at 1:1000 ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TBG, antibody at 1:200 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Sheep Un-conjugated RIA   1 mL Log in to see 6 to 8 Days
$324.50
Details
Hormone Mouse Un-conjugated   1 mg Log in to see 4 to 5 Days
$286.00
Details
Human Mouse Un-conjugated   1 mg Log in to see 4 to 5 Days
$286.00
Details
Human Sheep Un-conjugated ID, IHC (fro)   1 mL Log in to see 6 to 8 Days
$456.50
Details

SERPINA7 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 Antibodies

  1. Human Polyclonal SERPINA7 Primary Antibody for WB - ABIN1881790 : Mori, Miura, Takeuchi, Igarashi, Sugiura, Saito, Oiso: Gene amplification as a cause of inherited thyroxine-binding globulin excess in two Japanese families. in The Journal of clinical endocrinology and metabolism 1996 (PubMed)
    Show all 6 references for ABIN1881790

  2. Human Monoclonal SERPINA7 Primary Antibody for ELISA, WB - ABIN1724893 : Duhan, Patston: Explanation for the high heat stability of thyroxine binding globulin-Chicago. in Endocrine regulations 2010 (PubMed)
    Show all 2 references for ABIN1724893

  3. Human Monoclonal SERPINA7 Primary Antibody for ICC, FACS - ABIN1724894 : Yan, Yan, Ou: Human thyroxine binding globulin (TBG) promoter directs efficient and sustaining transgene expression in liver-specific pattern. in Gene 2012 (PubMed)
    Show all 2 references for ABIN1724894

  4. Human Polyclonal SERPINA7 Primary Antibody for FACS, IHC (p) - ABIN390670 : Domingues, Font, Sobrinho, Bugalho: A novel variant in Serpina7 gene in a family with thyroxine-binding globulin deficiency. in Endocrine 2009 (PubMed)

More Antibodies against serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 Interaction Partners

Mouse (Murine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) interaction partners

  1. the TBG promoter has a role in sustaining transgene expression in liver-specific pattern

Human serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) interaction partners

  1. mutation in a liver-specific enhancer region of the TBG gene caused inherited TBG deficiency. To our knowledge, the present study is the first report of an inherited endocrine disorder caused by a mutation in an enhancer region.

  2. TBG allosteric regulation is entropy driven. The presence of multiple S states may allow more efficient T4 release due to protease activity.

  3. the TBG promoter has a role in sustaining transgene expression in liver-specific pattern

  4. Freshly isolated TBG-Chicago exists in loop expelled conformation. At 37C, the protein readily converts to a more stable loop inserted conformation with enhanced heat stability.

  5. an intragenic A/G polymorphism (125 bp upstream from exon 2) was identified. complete TBG deficiency was homozygous for the polymorphic TBG allele.

  6. Two novel variants in the thyroxine-binding globulin gene behind the diagnosis of TBG deficiency. homozygous. One involved codon 23 (TCA-->TAA) and the other, codon 223.

  7. Loop variants of the serpin thyroxine-binding globulin: implications for hormone release upon limited proteolysis.

  8. guanine deletion at position 1711, codon 201 (Asp (show ASIP Antibodies)) in exon 2 (GAC (show GLS Antibodies) --> AC) led to a frame shift and premature termination at codon 206, causing a short TBG protein of 205 amino acids (AA) compared to 395 AA of the normal TBG.

  9. new serpina7 gene variant in three members of the same family results in the replacement of the normal asparagine 233 by isoleucine and, subsequently, in disruption of a glycosylation site

  10. The first exon (exon 0) is a short noncoding sequence located 1.62 kilobase pairs (kbp (show KIAA1279 Antibodies)) upstream from exon 1. HNF-1 (show HNF1A Antibodies) site (located 65 bp upstream of the TSS (show RPL38 Antibodies)) is required for the hepatocyte specific expression of the hTBG gene.

Pig (Porcine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) interaction partners

  1. polymorphism in exon 2 in thyroxine-binding globulin is a candidate for the causative variation affecting testis size in boars.

serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) Antigen Profile

Protein Summary

There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Gene names and symbols associated with SERPINA7

  • serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 (Serpina7) antibody
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 (SERPINA7) antibody
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 (Serpina7) antibody
  • C730040N12Rik antibody
  • TBG antibody
  • THYROXINE-BINDING GLOBULIN antibody

Protein level used designations for SERPINA7

T4-binding globulin , serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antipeptidase, antitrypsin), member 7 , serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 , serpin A7 , thyroxine-binding globulin , thyroxin-binding globulin , serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 , serine (or cysteine) proteinase inhibitor clade A (alpha-1 antiproteinase antitrypsin) member 7 , serine (or cysteine) proteinase inhibitor, clade A, member 7

GENE ID SPECIES
331535 Mus musculus
6906 Homo sapiens
81806 Rattus norvegicus
282518 Bos taurus
481007 Canis lupus familiaris
397125 Sus scrofa
443462 Ovis aries
465791 Pan troglodytes
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