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seryl-tRNA Synthetase 2, Mitochondrial Proteins (SARS2)

SARS2 encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. Additionally we are shipping SARS2 Antibodies (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SARS2 71984 Q9JJL8
SARS2 54938 Q9NP81
Rat SARS2 SARS2 292759  
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Top SARS2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,367.83
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SARS2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for seryl-tRNA Synthetase 2, Mitochondrial (SARS2) Interaction Partners

Mouse (Murine) seryl-tRNA Synthetase 2, Mitochondrial (SARS2) interaction partners

  1. Identification of an array of 4 CCAAT box elements required for efficient transcription of the Sars2 gene.

Human seryl-tRNA Synthetase 2, Mitochondrial (SARS2) interaction partners

  1. These data further support that the mitochondrial tRNA(Ser(UCN)) gene is the hot spot for mutations associated with hearing loss.

  2. Late-onset mitochondrial myopathy with dystrophic changes due to a G7497A mutation in the mitochondrial tRNA(Ser(UCN)) gene.

  3. NF-Y type CCAAT boxes are found preferentially in bidirectional Mrps12 (show MRPS12 Proteins)/Sarsm promoters, but many such promoters lack them and must be regulated in another way.

SARS2 Protein Profile

Protein Summary

This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with SARS2

  • seryl-aminoacyl-tRNA synthetase 2 (Sars2)
  • seryl-tRNA synthetase 2, mitochondrial (SARS2)
  • seryl-tRNA synthetase 2, mitochondrial (Sars2)
  • 2410015F05Rik protein
  • D7Ertd353e protein
  • mtSerRS protein
  • SARS protein
  • SARSM protein
  • SerRS protein
  • SerRSmt protein
  • SERS protein
  • SYS protein

Protein level used designations for SARS2

serine--tRNA ligase, mitochondrial , seryl-tRNA synthetase, mitochondrial , seryl-tRNA(Ser/Sec) synthetase , mitochondrial seryl-tRNA synthetase , serine tRNA ligase 2, mitochondrial , serine-tRNA ligase, mitochondrial , seryl-aminoacyl-tRNA synthetase 2 , serRSmt

GENE ID SPECIES
71984 Mus musculus
54938 Homo sapiens
292759 Rattus norvegicus
282060 Bos taurus
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