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Browse our anti-PRKAA2 (PRKAA2) Antibodies

Full name:
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit Antibodies (PRKAA2)
On are 248 Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) Antibodies from 27 different suppliers available. Additionally we are shipping PRKAA2 Kits (11) and PRKAA2 Proteins (9) and many more products for this protein. A total of 279 PRKAA2 products are currently listed.
2310008I11Rik, A830082D05, Ampk, AMPK2, AMPKA2, AMPKalpha2, PRKAA, prkaa1, PRKAA2
list all antibodies Gene Name GeneID UniProt
PRKAA2 5563 P54646
PRKAA2 78975 Q09137
PRKAA2 108079 Q8BRK8

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anti-Human PRKAA2 Antibodies:

anti-Rat (Rattus) PRKAA2 Antibodies:

anti-Mouse (Murine) PRKAA2 Antibodies:

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Top referenced anti-PRKAA2 Antibodies

  1. Human Polyclonal PRKAA2 Primary Antibody for WB - ABIN391306 : Minokoshi, Alquier, Furukawa, Kim, Lee, Xue, Mu, Foufelle, Ferré, Birnbaum, Stuck, Kahn: AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. in Nature 2004 (PubMed)
    Show all 4 references for ABIN391306

  2. Human Polyclonal PRKAA2 Primary Antibody for EIA, IHC (p) - ABIN954298 : Bungard, Fuerth, Zeng, Faubert, Maas, Viollet, Carling, Thompson, Jones, Berger: Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. in Science (New York, N.Y.) 2010 (PubMed)
    Show all 4 references for ABIN954298

  3. Human Polyclonal PRKAA2 Primary Antibody for IHC (p), WB - ABIN391058 : Hamilton, Stapleton, ODonnell, Kung, Dalal, Kemp, Witters: An activating mutation in the gamma1 subunit of the AMP-activated protein kinase. in FEBS letters 2001 (PubMed)
    Show all 3 references for ABIN391058

  4. Cow (Bovine) Polyclonal PRKAA2 Primary Antibody for WB - ABIN151705 : Rubin, Magliola, Feng, Jones, Hale: Metabolic activation of AMP kinase in vascular smooth muscle. in Journal of applied physiology (Bethesda, Md. : 1985) 2004 (PubMed)
    Show all 3 references for ABIN151705

  5. Human Polyclonal PRKAA2 Primary Antibody for EIA, IHC (p) - ABIN359569 : Cheung, Liu, Chow, Lee, Ip, Ho, Fan: Preoperative plasma transcript AA454543 level is an independent prognostic factor for hepatocellular carcinoma after partial hepatectomy. in Neoplasia (New York, N.Y.) 2006 (PubMed)
    Show all 2 references for ABIN359569

  6. Human Polyclonal PRKAA2 Primary Antibody for WB - ABIN2786849 : Qin, De Vries: alpha2 But not alpha1 AMP-activated protein kinase mediates oxidative stress-induced inhibition of retinal pigment epithelium cell phagocytosis of photoreceptor outer segments. in The Journal of biological chemistry 2008 (PubMed)

  7. Cow (Bovine) Polyclonal PRKAA2 Primary Antibody for EIA, WB - ABIN499148 : Dong, Zhang, Liang, Xie, Zhao, Asfa, Choi, Zou: Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo. in Circulation 2010 (PubMed)

  8. Human Polyclonal PRKAA2 Primary Antibody for IF (p), IHC (p) - ABIN680458 : Fu, Zhu, Dodson, Du: AMP-activated protein kinase stimulates Warburg-like glycolysis and activation of satellite cells during muscle regeneration. in The Journal of biological chemistry 2015 (PubMed)

More Antibodies against PRKAA2 Interaction Partners

Human Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) interaction partners

  1. Binding of miR (show MLXIP Antibodies)-27a to the 3'-UTR (show UTS2R Antibodies) of the AMPKalpha2 gene was required to increase the sensitivity of breast cancer cells to metformin.

  2. human cells were infected with lentiviruses expressing shRNA targeting both alpha1 and alpha2 AMPK (show PRKAA1 Antibodies) subunits. AMPK (show PRKAA1 Antibodies) activation inhibits Gli1 (show GLI1 Antibodies)-driven proliferation and that this effect is linked to Ser408 phosphorylation, which represents a key metabolic checkpoint for Hh signaling.

  3. These data are in accordance with R6 binding directly to AMPKbeta2 when both proteins detach from the diminishing glycogen (show GYS1 Antibodies) particle, which is simultaneous with increased AMPKbeta2 Thr (show TRH Antibodies)-148 autophosphorylation.

  4. p-AMPKalpha (show GRK4 Antibodies) was associated with cervical carcinogenesis, and high expression of AMPKalpha2 was correlated with better disease-free survival in patients with early-stage cervical cancer

  5. AMPK-alpha-2 binds to ER-alpha (show ESR1 Antibodies), as well as ER-beta (show ESR2 Antibodies).

  6. Data show that activated AMP-activated protein kinase (AMPK) limits retinal pigment epithelial cells (RPE (show RPE Antibodies)) phagocytic activity by abolishing retinal photoreceptor cell outer segment (POS)-induced activation of c-mer proto-oncogene tyrosine kinase (MerTK (show MERTK Antibodies)).

  7. AMPKalpha (show GRK4 Antibodies) signalling suppresses EMT (show ITK Antibodies) and secretion of chemokines in renal tubular epithelia through interaction with CK2beta (show CSNK2B Antibodies) to attenuate renal injury.

  8. Data (including data from studies in knockout mice) suggest AMPK (show PRKAA1 Antibodies) activation (AMPKa1 (show PRKAA1 Antibodies) or AMPKa2) suppresses inflammation in vascular smooth muscle cells by down-regulation of STAT1 (show STAT1 Antibodies) signaling and up-regulation of MKP-1 (dual specificity phosphatase 1 (show DUSP1 Antibodies)).

  9. A subunit composition of AMPK (show PRKAA1 Antibodies) (alpha2beta2gamma1) is preferred for colorectal cancer cell survival, at least in part, by stabilizing the tumor-specific expression of PGC1B (show PPARGC1B Antibodies).

  10. CaMKKbeta-AMPKalpha2 signaling contributes to mitotic Golgi fragmentation and the G2/M transition in mammalian cells.

Cow (Bovine) Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) interaction partners

  1. Endometrial inflammatory responses to lipopolysaccharide were also reduced by small molecules that activate or inhibit the intracellular sensor of energy, AMP-activated protein kinase (AMPK).

  2. The investigation of PRKAA2 genetic polymorphisms in three Chinese indigenous bovine breeds [Qinchuan (n = 328), Nanyang (n = 278), Jiaxian (n = 148)] and yak (n = 57), is reported.

  3. These data show that the AMPK (show PRKAA1 Antibodies) activator AICAR (show ATIC Antibodies) is inhibitory to nuclear maturation in bovine oocytes due to activation of AMPK (show PRKAA1 Antibodies) [AMP-activated protein kinase alpha (show PAK1 Antibodies) 1 subunit].

Mouse (Murine) Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) interaction partners

  1. Collectively, our data support the notion that the activation of AMPKalpha2 contributes to the atrophic effects of denervation.

  2. The activation of AMPKalpha2 in neutrophils is a decisive event in the initiation of vascular repair after ischemia.

  3. AMPKalpha2 deletion induces vascular smooth muscle cell phenotype switching and promotes features of atherosclerotic plaque.

  4. Data show that metformin may protect against ciaplatin induced acute kidney injury (AKI) through stimulating AMPKalpha (show GRK4 Antibodies) activation.

  5. Suggest that E2 treatment ameliorates estrogen deficiency-induced changes in cardiac contractile function possibly through an AMPK (show PRKAA1 Antibodies)-dependent mechanism.

  6. AMPKalpha2 deletion and high-fat feeding adverse effects are not additive on heart function and myocardial ischemic tolerance.

  7. AMPKalpha2 isoform plays a fundamental role in anti-oxidant stress and anti-senescence

  8. AMPKalpha2 is involved in post-transcriptional and not transcriptional regulation of PDK4 (show PDK4 Antibodies) in muscle.

  9. Deletion of the AMPK (show PRKAA1 Antibodies) alpha-subunits improves oral but not intraperitoneal glucose tolerance.

  10. PKD1 (show PKD1 Antibodies) phosphorylates AMPKalpha2 at Ser485/491, thus diminishing AMPK (show PRKAA1 Antibodies) activity.

Pig (Porcine) Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) interaction partners

  1. Single SNP and haplotype analyses revealed weak associations between the PRKAA2 genotypes and loin muscle area in the investigated populations.

PRKAA2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Alternative names and synonyms associated with PRKAA2

  • protein kinase, AMP-activated, alpha 2 catalytic subunit (prkaa2) antibody
  • protein kinase, AMP-activated, alpha 2 catalytic subunit (PRKAA2) antibody
  • protein kinase, AMP-activated, alpha 2 catalytic subunit (Prkaa2) antibody
  • 2310008I11Rik antibody
  • A830082D05 antibody
  • Ampk antibody
  • AMPK2 antibody
  • AMPKA2 antibody
  • AMPKalpha2 antibody
  • PRKAA antibody
  • prkaa1 antibody
  • PRKAA2 antibody

Protein level used designations for PRKAA2

SNF1-like protein AMPK , 5'-AMP-activated protein kinase catalytic subunit alpha-2 , 5'-AMP-activated protein kinase alpha-2 catalytic subunit , protein kinase, AMP-activated, alpha 2 catalytic subunit , AMPKalpha2 , ampka2 , AMP-activated protein kinase alpha 2 catalytic subunit , ACACA kinase , AMPK subunit alpha-2 , HMGCR kinase , acetyl-CoA carboxylase kinase , hydroxymethylglutaryl-CoA reductase kinase , 5'-AMP-activated protein kinase, catalytic alpha-2 chain , AMPK-alpha-2 chain , AMP-activated protein kinase , AMPK alpha-2 chain , AMP-activated protein kinase alpha-2 variant B , AMP-activated protein kinase alpha 2 , protein kinase AMP-activated alpha 2 catalytic subunit , AMPK-activated protein kinase alpha-2 subunit

399172 Xenopus laevis
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572074 Danio rerio
741802 Pan troglodytes
780945 Meleagris gallopavo
100019066 Monodelphis domestica
100127210 Ovis aries
100172060 Pongo abelii
100216099 Xenopus (Silurana) tropicalis
5563 Homo sapiens
538954 Bos taurus
78975 Rattus norvegicus
108079 Mus musculus
489571 Canis lupus familiaris
397504 Sus scrofa
100034159 Equus caballus
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