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Browse our anti-PRKAA2 (PRKAA2) Antibodies

Full name:
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit Antibodies (PRKAA2)
On www.antibodies-online.com are 235 Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) Antibodies from 26 different suppliers available. Additionally we are shipping PRKAA2 Kits (11) and PRKAA2 Proteins (8) and many more products for this protein. A total of 265 PRKAA2 products are currently listed.
Synonyms:
2310008I11Rik, A830082D05, Ampk, AMPK2, AMPKA2, AMPKalpha2, PRKAA, prkaa1, PRKAA2
list all antibodies Gene Name GeneID UniProt
PRKAA2 5563 P54646
PRKAA2 78975 Q09137
PRKAA2 108079 Q8BRK8

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anti-Human PRKAA2 Antibodies:

anti-Rat (Rattus) PRKAA2 Antibodies:

anti-Mouse (Murine) PRKAA2 Antibodies:

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Top referenced anti-PRKAA2 Antibodies

  1. Human Polyclonal PRKAA2 Primary Antibody for WB - ABIN391306 : Minokoshi, Alquier, Furukawa, Kim, Lee, Xue, Mu, Foufelle, Ferré, Birnbaum, Stuck, Kahn: AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. in Nature 2004 (PubMed)
    Show all 4 references for ABIN391306

  2. Human Polyclonal PRKAA2 Primary Antibody for EIA, IHC (p) - ABIN954298 : Bungard, Fuerth, Zeng, Faubert, Maas, Viollet, Carling, Thompson, Jones, Berger: Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. in Science (New York, N.Y.) 2010 (PubMed)
    Show all 4 references for ABIN954298

  3. Human Polyclonal PRKAA2 Primary Antibody for IHC (p), WB - ABIN391058 : Hamilton, Stapleton, ODonnell, Kung, Dalal, Kemp, Witters: An activating mutation in the gamma1 subunit of the AMP-activated protein kinase. in FEBS letters 2001 (PubMed)
    Show all 3 references for ABIN391058

  4. Human Polyclonal PRKAA2 Primary Antibody for EIA, IHC (p) - ABIN359569 : Cheung, Liu, Chow, Lee, Ip, Ho, Fan: Preoperative plasma transcript AA454543 level is an independent prognostic factor for hepatocellular carcinoma after partial hepatectomy. in Neoplasia (New York, N.Y.) 2006 (PubMed)
    Show all 2 references for ABIN359569

  5. Human Polyclonal PRKAA2 Primary Antibody for WB - ABIN2786849 : Qin, De Vries: alpha2 But not alpha1 AMP-activated protein kinase mediates oxidative stress-induced inhibition of retinal pigment epithelium cell phagocytosis of photoreceptor outer segments. in The Journal of biological chemistry 2008 (PubMed)

  6. Cow (Bovine) Polyclonal PRKAA2 Primary Antibody for EIA, WB - ABIN499148 : Dong, Zhang, Liang, Xie, Zhao, Asfa, Choi, Zou: Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo. in Circulation 2010 (PubMed)

  7. Human Polyclonal PRKAA2 Primary Antibody for IF (p), IHC (p) - ABIN680458 : Fu, Zhu, Dodson, Du: AMP-activated protein kinase stimulates Warburg-like glycolysis and activation of satellite cells during muscle regeneration. in The Journal of biological chemistry 2015 (PubMed)

More Antibodies against PRKAA2 Interaction Partners

Human Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) interaction partners

  1. These data are in accordance with R6 binding directly to AMPKbeta2 when both proteins detach from the diminishing glycogen (show GYS1 Antibodies) particle, which is simultaneous with increased AMPKbeta2 Thr (show TRH Antibodies)-148 autophosphorylation.

  2. p-AMPKalpha (show GRK4 Antibodies) was associated with cervical carcinogenesis, and high expression of AMPKalpha2 was correlated with better disease-free survival in patients with early-stage cervical cancer

  3. AMPK-alpha-2 binds to ER-alpha (show ESR1 Antibodies), as well as ER-beta (show ESR2 Antibodies).

  4. Data show that activated AMP-activated protein kinase (AMPK) limits retinal pigment epithelial cells (RPE (show RPE Antibodies)) phagocytic activity by abolishing retinal photoreceptor cell outer segment (POS)-induced activation of c-mer proto-oncogene tyrosine kinase (MerTK (show MERTK Antibodies)).

  5. AMPKalpha (show GRK4 Antibodies) signalling suppresses EMT (show ITK Antibodies) and secretion of chemokines in renal tubular epithelia through interaction with CK2beta (show CSNK2B Antibodies) to attenuate renal injury.

  6. Data (including data from studies in knockout mice) suggest AMPK (show PRKAA1 Antibodies) activation (AMPKa1 (show PRKAA1 Antibodies) or AMPKa2) suppresses inflammation in vascular smooth muscle cells by down-regulation of STAT1 (show STAT1 Antibodies) signaling and up-regulation of MKP-1 (dual specificity phosphatase 1 (show DUSP1 Antibodies)).

  7. A subunit composition of AMPK (show PRKAA1 Antibodies) (alpha2beta2gamma1) is preferred for colorectal cancer cell survival, at least in part, by stabilizing the tumor-specific expression of PGC1B (show PPARGC1B Antibodies).

  8. CaMKKbeta-AMPKalpha2 signaling contributes to mitotic Golgi fragmentation and the G2/M transition in mammalian cells.

  9. The basal level of ERK (show EPHB2 Antibodies) phosphorylation was suppressed in cells treated with siRNA against PRKAA2 (AMPK-knockdown cells).

  10. These data define the master metabolic regulator AMPK (show PRKAA1 Antibodies) as a novel stress granule constituent that also controls their biogenesis.

Cow (Bovine) Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) interaction partners

  1. Endometrial inflammatory responses to lipopolysaccharide were also reduced by small molecules that activate or inhibit the intracellular sensor of energy, AMP-activated protein kinase (AMPK).

  2. The investigation of PRKAA2 genetic polymorphisms in three Chinese indigenous bovine breeds [Qinchuan (n = 328), Nanyang (n = 278), Jiaxian (n = 148)] and yak (n = 57), is reported.

  3. These data show that the AMPK (show PRKAA1 Antibodies) activator AICAR (show ATIC Antibodies) is inhibitory to nuclear maturation in bovine oocytes due to activation of AMPK (show PRKAA1 Antibodies) [AMP-activated protein kinase alpha (show PAK1 Antibodies) 1 subunit].

Mouse (Murine) Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) interaction partners

  1. AMPKalpha2 isoform plays a fundamental role in anti-oxidant stress and anti-senescence

  2. AMPKalpha2 is involved in post-transcriptional and not transcriptional regulation of PDK4 (show PDK4 Antibodies) in muscle.

  3. Deletion of the AMPK (show PRKAA1 Antibodies) alpha-subunits improves oral but not intraperitoneal glucose tolerance.

  4. PKD1 (show PKD1 Antibodies) phosphorylates AMPKalpha2 at Ser485/491, thus diminishing AMPK (show PRKAA1 Antibodies) activity.

  5. In conclusion, our findings reveal a new functional role of activating AMPK (show PRKAA1 Antibodies) in the CNS to attenuate inflammatory responses and acute lung injury in sepsis.

  6. Data (including data from knockout mice) suggest expression levels/phosphorylation of Ampk (show PRKAA1 Antibodies)-alpha1/Ampk (show PRKAA1 Antibodies)-alpha2 are up-regulated in intestinal mucosa by ingestion of alpha-linolenic acid (which inhibits high-fat diet-induced hypertriglyceridemia).

  7. AMPKalpha (show GRK4 Antibodies) signalling suppresses EMT (show ITK Antibodies) and secretion of chemokines in renal tubular epithelia through interaction with CK2beta (show CSNK2B Antibodies) to attenuate renal injury.

  8. Data (including data from studies in knockout mice) suggest that AMPKa1 (show PRKAA1 Antibodies) and AMPKa2 are key in gene expression regulation in skeletal muscle in acute exercise studies but not in longer exercise training adaptation studies.

  9. the current data suggests that activation of AMPK (show PRKAA1 Antibodies) signaling is sufficient but not required for exercise-induced accumulation in mitochondrial FAT/CD36 (show CD36 Antibodies).

  10. The increase in nuclear PPARalpha (show PPARA Antibodies) protein by four-week exercise training under the intermittent hypoxia was dependent on AMPKalpha2 activation.

Pig (Porcine) Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) interaction partners

  1. Single SNP and haplotype analyses revealed weak associations between the PRKAA2 genotypes and loin muscle area in the investigated populations.

PRKAA2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Alternative names and synonyms associated with PRKAA2

  • protein kinase, AMP-activated, alpha 2 catalytic subunit (prkaa2) antibody
  • protein kinase, AMP-activated, alpha 2 catalytic subunit (PRKAA2) antibody
  • protein kinase, AMP-activated, alpha 2 catalytic subunit (Prkaa2) antibody
  • 2310008I11Rik antibody
  • A830082D05 antibody
  • Ampk antibody
  • AMPK2 antibody
  • AMPKA2 antibody
  • AMPKalpha2 antibody
  • PRKAA antibody
  • prkaa1 antibody
  • PRKAA2 antibody

Protein level used designations for PRKAA2

SNF1-like protein AMPK , 5'-AMP-activated protein kinase catalytic subunit alpha-2 , 5'-AMP-activated protein kinase alpha-2 catalytic subunit , protein kinase, AMP-activated, alpha 2 catalytic subunit , AMPKalpha2 , ampka2 , AMP-activated protein kinase alpha 2 catalytic subunit , ACACA kinase , AMPK subunit alpha-2 , HMGCR kinase , acetyl-CoA carboxylase kinase , hydroxymethylglutaryl-CoA reductase kinase , 5'-AMP-activated protein kinase, catalytic alpha-2 chain , AMPK-alpha-2 chain , AMP-activated protein kinase , AMPK alpha-2 chain , AMP-activated protein kinase alpha-2 variant B , AMP-activated protein kinase alpha 2 , protein kinase AMP-activated alpha 2 catalytic subunit , AMPK-activated protein kinase alpha-2 subunit

GENE ID SPECIES
399172 Xenopus laevis
429110 Gallus gallus
445012 Canis lupus familiaris
572074 Danio rerio
741802 Pan troglodytes
780945 Meleagris gallopavo
100019066 Monodelphis domestica
100127210 Ovis aries
100172060 Pongo abelii
100216099 Xenopus (Silurana) tropicalis
5563 Homo sapiens
538954 Bos taurus
78975 Rattus norvegicus
108079 Mus musculus
489571 Canis lupus familiaris
397504 Sus scrofa
100034159 Equus caballus
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