Browse our anti-PRKAA2 (PRKAA2) Antibodies

Full name:
anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit Antibodies (PRKAA2)
On www.antibodies-online.com are 246 Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) Antibodies from 28 different suppliers available. Additionally we are shipping PRKAA2 Kits (12) and PRKAA2 Proteins (10) and many more products for this protein. A total of 279 PRKAA2 products are currently listed.
Synonyms:
2310008I11Rik, A830082D05, Ampk, AMPK2, AMPKA2, AMPKalpha2, PRKAA, prkaa1, PRKAA2
list all antibodies Gene Name GeneID UniProt
PRKAA2 5563 P54646
PRKAA2 78975 Q09137
PRKAA2 108079 Q8BRK8

Show all species

Show all synonyms

Most Popular Reactivities for anti-PRKAA2 (PRKAA2) Antibodies

Select your species and application

anti-Human PRKAA2 Antibodies:

anti-Rat (Rattus) PRKAA2 Antibodies:

anti-Mouse (Murine) PRKAA2 Antibodies:

All available anti-PRKAA2 Antibodies

Go to our pre-filtered search.

Top referenced anti-PRKAA2 Antibodies

  1. Human Polyclonal PRKAA2 Primary Antibody for EIA, IHC (p) - ABIN954298 : Bungard, Fuerth, Zeng, Faubert, Maas, Viollet, Carling, Thompson, Jones, Berger: Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. in Science (New York, N.Y.) 2010 (PubMed)
    Show all 4 references for 954298

  2. Human Polyclonal PRKAA2 Primary Antibody for WB - ABIN391306 : Minokoshi, Alquier, Furukawa, Kim, Lee, Xue, Mu, Foufelle, Ferré, Birnbaum, Stuck, Kahn: AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. in Nature 2004 (PubMed)
    Show all 4 references for 391306

  3. Human Polyclonal PRKAA2 Primary Antibody for IHC (p), WB - ABIN391058 : Hamilton, Stapleton, ODonnell, Kung, Dalal, Kemp, Witters: An activating mutation in the gamma1 subunit of the AMP-activated protein kinase. in FEBS letters 2001 (PubMed)
    Show all 3 references for 391058

  4. Cow (Bovine) Polyclonal PRKAA2 Primary Antibody for WB - ABIN151705 : Rubin, Magliola, Feng, Jones, Hale: Metabolic activation of AMP kinase in vascular smooth muscle. in Journal of applied physiology (Bethesda, Md. : 1985) 2004 (PubMed)
    Show all 3 references for 151705

  5. Human Polyclonal PRKAA2 Primary Antibody for EIA, IHC (p) - ABIN359569 : Cheung, Liu, Chow, Lee, Ip, Ho, Fan: Preoperative plasma transcript AA454543 level is an independent prognostic factor for hepatocellular carcinoma after partial hepatectomy. in Neoplasia (New York, N.Y.) 2006 (PubMed)
    Show all 2 references for 359569

  6. Human Polyclonal PRKAA2 Primary Antibody for IHC (p), WB - ABIN391608 : Wyatt, Mustard, Pearson, Dallas, Atkinson, Kumar, Peers, Hardie, Evans: AMP-activated protein kinase mediates carotid body excitation by hypoxia. in The Journal of biological chemistry 2007 (PubMed)
    Show all 2 references for 391608

  7. Human Polyclonal PRKAA2 Primary Antibody for IF (p), IHC (p) - ABIN680458 : Fu, Zhu, Dodson, Du: AMP-activated protein kinase stimulates Warburg-like glycolysis and activation of satellite cells during muscle regeneration. in The Journal of biological chemistry 2015 (PubMed)
    Show all 2 references for 680458

  8. Cow (Bovine) Polyclonal PRKAA2 Primary Antibody for WB - ABIN2786849 : Qin, De Vries: alpha2 But not alpha1 AMP-activated protein kinase mediates oxidative stress-induced inhibition of retinal pigment epithelium cell phagocytosis of photoreceptor outer segments. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against PRKAA2 Interaction Partners

Human Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) interaction partners

  1. Results highlight the contribution of AMPKalpha2 as a mechanism for controlling bladder cancer growth by regulating proliferation through mTOR (show FRAP1 Antibodies) suppression and induction of p27 (show PAK2 Antibodies) protein levels, thus indicating how AMPKalpha2 loss may contribute to tumorigenesis.

  2. AMPK (show PRKAA1 Antibodies) phosphorylation of cortactin (show CTTN Antibodies) followed by SIRT1 (show SIRT1 Antibodies) deacetylation modulates the interaction of cortactin (show CTTN Antibodies) and cortical-actin in response to shear stress. Functionally, this AMPK (show PRKAA1 Antibodies)/SIRT1 (show SIRT1 Antibodies) coregulated cortactin (show CTTN Antibodies)-F-actin dynamics is required for endothelial nitric oxide synthase (show NOS3 Antibodies) subcellular translocation/activation and is atheroprotective.

  3. Data suggest that the AMPK (show PRKAA1 Antibodies)-TBC1D4 (show TBC1D4 Antibodies) signaling axis is likely mediating the improved muscle insulin (show INS Antibodies) sensitivity after contraction/exercise and illuminates an important and physiologically relevant role of AMPK (show PRKAA1 Antibodies) in skeletal muscle.

  4. inactivation of AMPKalpha2, but not AMPKalpha1 (show PRKAA1 Antibodies), abrogates the tumor attenuation caused by UBE2O (show UBE2O Antibodies) loss.

  5. Our findings demonstrate that the AMPKalpha2 catalytic subunit in Kiss1 (show KISS1 Antibodies) cells is dispensable for body weight and reproductive function in mice but is necessary for the reproductive adaptations to conditions of acute metabolic distress.

  6. Binding of miR (show MLXIP Antibodies)-27a to the 3'-UTR (show UTS2R Antibodies) of the AMPKalpha2 gene was required to increase the sensitivity of breast cancer cells to metformin.

  7. human cells were infected with lentiviruses expressing shRNA targeting both alpha1 and alpha2 AMPK (show PRKAA1 Antibodies) subunits. AMPK (show PRKAA1 Antibodies) activation inhibits Gli1 (show GLI1 Antibodies)-driven proliferation and that this effect is linked to Ser408 phosphorylation, which represents a key metabolic checkpoint for Hh signaling.

  8. These data are in accordance with R6 binding directly to AMPKbeta2 when both proteins detach from the diminishing glycogen (show GYS1 Antibodies) particle, which is simultaneous with increased AMPKbeta2 Thr (show TRH Antibodies)-148 autophosphorylation.

  9. p-AMPKalpha (show GRK4 Antibodies) was associated with cervical carcinogenesis, and high expression of AMPKalpha2 was correlated with better disease-free survival in patients with early-stage cervical cancer

  10. AMPK-alpha-2 binds to ER-alpha (show ESR1 Antibodies), as well as ER-beta (show ESR2 Antibodies).

Cow (Bovine) Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) interaction partners

  1. Endometrial inflammatory responses to lipopolysaccharide were also reduced by small molecules that activate or inhibit the intracellular sensor of energy, AMP-activated protein kinase (AMPK).

  2. The investigation of PRKAA2 genetic polymorphisms in three Chinese indigenous bovine breeds [Qinchuan (n = 328), Nanyang (n = 278), Jiaxian (n = 148)] and yak (n = 57), is reported.

  3. These data show that the AMPK (show PRKAA1 Antibodies) activator AICAR (show ATIC Antibodies) is inhibitory to nuclear maturation in bovine oocytes due to activation of AMPK (show PRKAA1 Antibodies) [AMP-activated protein kinase alpha (show PAK1 Antibodies) 1 subunit].

Mouse (Murine) Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) interaction partners

  1. Rac1 and AMPK (show PRKAA1 Antibodies) together account for almost the entire ex vivo contraction response in muscle glucose transport, whereas only Rac1, but not alpha2 AMPK (show PRKAA1 Antibodies), regulates muscle glucose uptake during submaximal exercise in vivo.

  2. we used the Cre-loxP system to knock down AMPKalpha2 expression in renal epithelial cells. Combining this approach with the systemic deletion of AMPKalpha1 (show PRKAA1 Antibodies) we achieved reduced renal AMPK (show PRKAA1 Antibodies) activity, accompanied by a shift to a moderate water- and salt-wasting phenotype. Thus we confirm the physiologically relevant role of AMPK (show PRKAA1 Antibodies) in the kidney.

  3. AMPK (show PRKAA1 Antibodies) phosphorylation of cortactin (show CTTN Antibodies) followed by SIRT1 (show SIRT1 Antibodies) deacetylation modulates the interaction of cortactin (show CTTN Antibodies) and cortical-actin in response to shear stress. Functionally, this AMPK (show PRKAA1 Antibodies)/SIRT1 (show SIRT1 Antibodies) coregulated cortactin (show CTTN Antibodies)-F-actin dynamics is required for endothelial nitric oxide synthase (show NOS3 Antibodies) subcellular translocation/activation and is atheroprotective.

  4. Findings show that decreased AMPK (show PRKAA1 Antibodies) activity in muscle leads to decreased voluntary activity which is not due to secondary abnormalities in dopamine levels in the ventral striatum or sensitivity to cocaine. Thus, decreased voluntary activity in AMPK (show PRKAA1 Antibodies) muscle deficient mice is most likely unrelated to regulation of brain dopamine content and metabolism.

  5. Hypoxia reduces HNF4alpha/MODY1 (show HNF4A Antibodies) protein expression in pancreatic beta-cells by activating AMP-activated protein kinase.

  6. These studies reveal a novel mechanism in which CYP2J2 (show CYP2J2 Antibodies) and epoxyeicosatrienoic acids enhanced Akt1 (show AKT1 Antibodies) nuclear translocation through interaction with AMPKalpha2beta2gamma1 and protect against cardiac hypertrophy.

  7. Loss of AMPKalpha2 is associated with impaired control of vesicular stomatitis virus infection.

  8. AMPK (show PRKAA1 Antibodies)-mediated HSPB1 (show HSPB1 Antibodies) expression enhanced insulin (show INS Antibodies) sensitivity in the skeletal muscle.

  9. Collectively, our data support the notion that the activation of AMPKalpha2 contributes to the atrophic effects of denervation.

  10. The activation of AMPKalpha2 in neutrophils is a decisive event in the initiation of vascular repair after ischemia.

Pig (Porcine) Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) interaction partners

  1. Single SNP and haplotype analyses revealed weak associations between the PRKAA2 genotypes and loin muscle area in the investigated populations.

PRKAA2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Alternative names and synonyms associated with PRKAA2

  • protein kinase, AMP-activated, alpha 2 catalytic subunit (prkaa2) antibody
  • protein kinase, AMP-activated, alpha 2 catalytic subunit (PRKAA2) antibody
  • protein kinase, AMP-activated, alpha 2 catalytic subunit (Prkaa2) antibody
  • 2310008I11Rik antibody
  • A830082D05 antibody
  • Ampk antibody
  • AMPK2 antibody
  • AMPKA2 antibody
  • AMPKalpha2 antibody
  • PRKAA antibody
  • prkaa1 antibody
  • PRKAA2 antibody

Protein level used designations for PRKAA2

SNF1-like protein AMPK , 5'-AMP-activated protein kinase catalytic subunit alpha-2 , 5'-AMP-activated protein kinase alpha-2 catalytic subunit , protein kinase, AMP-activated, alpha 2 catalytic subunit , AMPKalpha2 , ampka2 , AMP-activated protein kinase alpha 2 catalytic subunit , ACACA kinase , AMPK subunit alpha-2 , HMGCR kinase , acetyl-CoA carboxylase kinase , hydroxymethylglutaryl-CoA reductase kinase , 5'-AMP-activated protein kinase, catalytic alpha-2 chain , AMPK-alpha-2 chain , AMP-activated protein kinase , AMPK alpha-2 chain , AMP-activated protein kinase alpha-2 variant B , AMP-activated protein kinase alpha 2 , protein kinase AMP-activated alpha 2 catalytic subunit , AMPK-activated protein kinase alpha-2 subunit

GENE ID SPECIES
399172 Xenopus laevis
429110 Gallus gallus
445012 Canis lupus familiaris
572074 Danio rerio
741802 Pan troglodytes
780945 Meleagris gallopavo
100019066 Monodelphis domestica
100127210 Ovis aries
100172060 Pongo abelii
100216099 Xenopus (Silurana) tropicalis
5563 Homo sapiens
538954 Bos taurus
78975 Rattus norvegicus
108079 Mus musculus
489571 Canis lupus familiaris
397504 Sus scrofa
100034159 Equus caballus
Selected quality suppliers for anti-PRKAA2 (PRKAA2) Antibodies
Did you look for something else?