IL-15 antibody
-
- Target See all IL-15 (IL15) Antibodies
- IL-15 (IL15) (Interleukin 15 (IL15))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Monoclonal
-
Conjugate
- This IL-15 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA
- Specificity
- At least two isoforms of IL-15 are known to exist.
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal IL-15 antibody was raised against a 13 amino acid peptide near the center of human IL-15.
- Isotype
- IgG
- Top Product
- Discover our top product IL15 Primary Antibody
-
-
- Application Notes
- IL-15 antibody can be used for detection of IL-15 by Western blot at 1 - 2 μg/mL.
- Comment
-
(IN) Interleukin-15
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Storage
- 4 °C/-20 °C
-
- Target
- IL-15 (IL15) (Interleukin 15 (IL15))
- Alternative Name
- IL15 (IL15 Products)
- Synonyms
- IL15 antibody, AI503618 antibody, IL-15 antibody, interleukin 15 antibody, IL15 antibody, Il15 antibody
- Background
-
Interleukin 15 (IL-15) is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.
Synonyms: Interleukin-15, IL15 - Molecular Weight
- 18 kDa
- Gene ID
- 3600
- NCBI Accession
- NP_000576
- Pathways
- JAK-STAT Signaling, Glycosaminoglycan Metabolic Process
-