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MAP2K3 antibody
MAP2K3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MAP2K3 Antibody
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Target
See all MAP2K3 Antibodies
MAP2K3
(Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
Reactivity
All reactivities for MAP2K3 antibodies
Human
Host
All hosts for MAP2K3 antibodies
Rabbit
Clonality
All clonalities for MAP2K3 antibodies
Polyclonal
Conjugate
All conjugates for MAP2K3 antibodies
This MAP2K3 antibody is un-conjugated
Application
All applications for MAP2K3 antibodies
Western Blotting (WB)
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Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Lyophilized
Storage
4 °C
Target Details for MAP2K3
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Target
MAP2K3
(Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
Alternative Name
MKK3 (MAP Kinase Kinase 3) (MAP2K3 Products )
Synonyms
MAPKK3 antibody, MEK3 antibody, MKK3 antibody, PRKMK3 antibody, SAPKK-2 antibody, SAPKK2 antibody, AW212142 antibody, Prkmk3 antibody, mMKK3b antibody, Mkk3 antibody, mitogen-activated protein kinase kinase 3 antibody, mitogen activated protein kinase kinase 3 antibody, MAP kinase activator XMEK3 antibody, MAP2K3 antibody, Map2k3 antibody, map2k3 antibody
Background
MKK3 is a protein kinase that phosphorylates the p38 MAPK but not ERK MAPK. Phosphorylation by MKK3 occurs on threonine and tyrosine residues and increases the activity of p38 to stimulate transcription factors ATF2 and Elk-1. MKK3, together with MKK6, serve as upstream regulators of p38 MAPK activation. A structural variant, MKK3b, has been identified that contains 29 more amino acids at its N-terminus.
Pathways
MAPK Signaling , TLR Signaling , Activation of Innate immune Response , Toll-Like Receptors Cascades , Autophagy , Signaling Events mediated by VEGFR1 and VEGFR2
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