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CD25 antibody
IL2RA
Reactivity: Human
FACS
Host: Mouse
Monoclonal
B-G3
unconjugated
Product Details anti-CD25 Antibody
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Target
See all CD25 (IL2RA) Antibodies
CD25 (IL2RA)
(Interleukin 2 Receptor, alpha (IL2RA))
Reactivity
All reactivities for CD25 antibodies
Human
Host
All hosts for CD25 antibodies
Mouse
Clonality
All clonalities for CD25 antibodies
Monoclonal
Conjugate
All conjugates for CD25 antibodies
This CD25 antibody is un-conjugated
Application
All applications for CD25 antibodies
Flow Cytometry (FACS)
Specificity
Recognises both soluble and membrane bound Interleukin 2 Receptor a chain (IL-2 Ra), a 55 kDa protein.
Purification
Ion exchange chromatography
Sterility
0.22 μm filtered
Immunogen
PHA activated T cells
Clone
B-G3
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1,0 mg/mL
Buffer
Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
Preservative
Without preservative
Storage
4 °C
Storage Comment
Store the antibody undiluted at 2-8 °C.
Target Details for CD25
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Target
CD25 (IL2RA)
(Interleukin 2 Receptor, alpha (IL2RA))
Alternative Name
CD25 / IL2RA (IL2RA Products )
Synonyms
CD25 antibody, IDDM10 antibody, IL2R antibody, TCGFR antibody, IL2RAC antibody, IL-2RA antibody, Il2r antibody, Ly-43 antibody, interleukin 2 receptor subunit alpha antibody, interleukin-2 receptor subunit alpha-like antibody, interleukin 2 receptor, alpha chain antibody, IL2RA antibody, Il2ra antibody, LOC100222957 antibody
Background
Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.Synonyms: IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, Interleukin-2 receptor alpha chain, TAC antigen, p55
Gene ID
3559
NCBI Accession
NP_000408
UniProt
P01589
Pathways
JAK-STAT Signaling , Growth Factor Binding , Activated T Cell Proliferation
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