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MBP/MBL antibody

MBP/MBL Reactivity: Human WB, IHC (fro), EIA, Neut Host: Mouse Monoclonal 3-00E-007 unconjugated
Catalog No. ABIN1108118
  • Target See all MBP/MBL Antibodies
    MBP/MBL (Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL))
    Reactivity
    • 6
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 4
    • 2
    • 1
    Mouse
    Clonality
    • 5
    • 2
    Monoclonal
    Conjugate
    • 6
    • 1
    This MBP/MBL antibody is un-conjugated
    Application
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Neutralization (Neut)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Clone
    3-00E-007
    Isotype
    IgG1
    Top Product
    Discover our top product MBP/MBL Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0,1 mg/mL
    Buffer
    PBS, 0,02 % sodium azide, 0,1 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    MBP/MBL (Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL))
    Alternative Name
    Mannan Binding Protein (MBP/MBL Products)
    Synonyms
    COLEC1 antibody, HSMBPC antibody, MBL antibody, MBL2D antibody, MBP antibody, MBP-C antibody, MBP1 antibody, MBPD antibody, pMBP-27 antibody, MBL1 antibody, cMBl antibody, collectin antibody, L-MBP antibody, MBL-C antibody, RaRF p28A antibody, mbl antibody, mannose binding lectin 2 antibody, mannose-binding lectin (protein C) 2 antibody, mannose-binding protein C-like antibody, MBL2 antibody, Mbl2 antibody, LOC100911854 antibody
    Background
    Mannose Binding Lectin (MBL) also called mannose- or mannan-binding protein (MBP) is a member of the group of Collectins. MBL is an oligomeric lectin that recognizes carbohydrates as mannose and N-acetylglucosamine on pathogens. MBL contains a cysteine rich, a collagen like and a carbohydrate recognition domain. It forms a complex with C1r/C1s like serine proteases designated MASPs that proteolytically cleave C4, C2 and C3. MBL is able to activate the complement pathway independent of the classical and alternative complement activation pathways. The MBL-MASP pathway (better known as the lectin pathway) is antibody and C1q-independent. MBL exhibits complement-dependent antibacterial activity and acts directly as an opsonic and therefore plays an important role in innate immunity. MBL is synthesized by hepatocytes and has been isolated from the liver or serum of various vertebrate species.Synonyms: MBL, MBL2, MBP, MBP-C, MBP1, Mannan-binding protein, Mannose-binding lectin, Mannose-binding protein C
    Gene ID
    9606
    UniProt
    P11226
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