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MBP/MBL Products

(Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL))
This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008].

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Featured MBP/MBL Categories

MBP/MBL Antibodies

High quality antibodies with extensive validation data.

MBP/MBL ELISA Kits

Reliable ELISA kits for a wide range of species.

MBP/MBL Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MBP/MBL Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application IHC (fro), ELISA, IF, ICC, IHC (p)
Validations
  • (3)
Cat. No. ABIN731663
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (fro), FACS, IA, BR
Validations
  • (5)
Cat. No. ABIN2191923
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (fro), FACS, IA
Validations
  • (5)
Cat. No. ABIN2191924
Quantity 100 μg
Datasheet Datasheet

Recommended MBP/MBL ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968436
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN1380039
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1979526
Quantity 96 tests
Datasheet Datasheet

Recommended MBP/MBL Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2181498
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2725272
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN5608462
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MBP/MBL products

Singh, Nathamu, Adame, Alire, Dumaop, Gouaux, Moore, Masliah: "Expression of mannose binding lectin in HIV-1-infected brain: implications for HIV-related neuronal damage and neuroAIDS." in: Neurobehavioral HIV medicine, Vol. 3, pp. 41-52, (2011) (PubMed).

Matthijsen, de Winther, Kuipers, van der Made, Weber, Herias, Gijbels, Buurman: "Macrophage-specific expression of mannose-binding lectin controls atherosclerosis in low-density lipoprotein receptor-deficient mice." in: Circulation, Vol. 119, Issue 16, pp. 2188-95, (2009) (PubMed).

Saevarsdottir, Oskarsson, Aspelund, Eiriksdottir, Vikingsdottir, Gudnason, Valdimarsson: "Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced risk." in: The Journal of experimental medicine, Vol. 201, Issue 1, pp. 117-25, (2005) (PubMed).

de Vries, Walter, Peutz-Kootstra, Wolfs, van Heurn, Buurman: "The mannose-binding lectin-pathway is involved in complement activation in the course of renal ischemia-reperfusion injury." in: The American journal of pathology, Vol. 165, Issue 5, pp. 1677-88, (2004) (PubMed).

Nauta, Castellano, Xu, Woltman, Borrias, Daha, van Kooten, Roos: "Opsonization with C1q and mannose-binding lectin targets apoptotic cells to dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 5, pp. 3044-50, (2004) (PubMed).

Nauta, Raaschou-Jensen, Roos, Daha, Madsen, Borrias-Essers, Ryder, Koch, Garred: "Mannose-binding lectin engagement with late apoptotic and necrotic cells." in: European journal of immunology, Vol. 33, Issue 10, pp. 2853-63, (2003) (PubMed).

Yang, Seeney, Wolter, Anders, McCormack, Tunnicliffe, Rabnott, Shaw, Dent, Kim, Zimmerman, Fong: "Mannose-binding lectin gene polymorphism predicts hospital admissions for COPD infections." in: Genes and immunity, Vol. 4, Issue 4, pp. 269-74, (2003) (PubMed).

Hisano, Matsushita, Fujita, Endo, Takebayashi: "Mesangial IgA2 deposits and lectin pathway-mediated complement activation in IgA glomerulonephritis." in: American journal of kidney diseases : the official journal of the National Kidney Foundation, Vol. 38, Issue 5, pp. 1082-8, (2001) (PubMed).

Muto, Takada, Matsumoto: "Biological activities of human mannose-binding lectin bound to two different ligand sugar structures, Lewis A and Lewis B antigens and high-mannose type oligosaccharides." in: Biochimica et biophysica acta, Vol. 1527, Issue 1-2, pp. 39-46, (2001) (PubMed).

Matsushita, Takahashi, Hatsuse, Kawakami, Fujita: "Human mannose-binding protein is identical to a component of Ra-reactive factor." in: Biochemical and biophysical research communications, Vol. 183, Issue 2, pp. 645-51, (1992) (PubMed).

Synonyms and alternative names related to MBP/MBL

mannose binding lectin 2 (MBL2), mannose-binding lectin (protein C) 2 (Mbl2), mannose-binding protein C-like (LOC100911854), cMBl, COLEC1, collectin, HSMBPC, L-MBP, MBL, mbl, MBL-C, MBL1, MBL2D, MBP, MBP-C, MBP1, MBPD, pMBP-27, RaRF p28A

Protein level used designations for MBP/MBL

  • collectin-1
  • mannan-binding lectin
  • mannose-binding lectin (protein C) 2, soluble (opsonic defect)
  • mannose-binding lectin 2, soluble (opsonic defect)
  • mannose-binding protein C
  • 27 kDa mannan-binding protein monomeric subunit
  • c-type lectin
  • mannose binding lectin, liver (A)
  • mannose-binding lectin 2
  • soluble mannose-binding lectin
  • MBP-C
  • MBP1
  • mannan-binding protein
  • RA-reactive factor P28A subunit
  • RARF/P28A
  • mannose binding lectin (C)
  • mannose binding lectin, liver (C)
  • Mannan-binding protein
  • Ra-reactive factor polysaccharide-binding component p28A
  • mannose-binding lectin (protein C) 2, soluble
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