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Paxillin antibody (C-Term)
PXN
Reactivity: Human, Mouse, Rat, Chicken
WB, IF
Host: Mouse
Monoclonal
PAX-14
unconjugated
Product Details anti-Paxillin Antibody
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Target
See all Paxillin (PXN) Antibodies
Paxillin (PXN)
Binding Specificity
All epitopes for Paxillin antibodies
AA 305-559, C-Term
Reactivity
All reactivities for Paxillin antibodies
Human, Mouse, Rat, Chicken
Host
All hosts for Paxillin antibodies
Mouse
Clonality
All clonalities for Paxillin antibodies
Monoclonal
Conjugate
All conjugates for Paxillin antibodies
This Paxillin antibody is un-conjugated
Application
All applications for Paxillin antibodies
Western Blotting (WB), Immunofluorescence (IF)
Specificity
This antibody reacts to Paxillin.
Purification
Affinity chromatography
Immunogen
C-terminal part of recombinant chicken paxillin (amino acids 305-559)
Clone
PAX-14
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Reconstitution
Restore with 1.2 % sodium acetate or neutral PBS
Concentration
0,1 mg/mL
Buffer
1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Paxillin
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Target
Paxillin (PXN)
Alternative Name
Paxillin / PXN (PXN Products )
Synonyms
AW108311 antibody, AW123232 antibody, Pax antibody, CG18061 antibody, CG18576 antibody, CG31794 antibody, CT40481 antibody, CT42454 antibody, DPaxillin antibody, DPxn antibody, DPxn37 antibody, Dmel\\CG31794 antibody, Dpax antibody, DpaxA antibody, PDLP antibody, dPax antibody, pax antibody, wu:fw71f12 antibody, PXN antibody, LOC100220858 antibody, paxillin antibody, Paxillin antibody, paxillin S homeolog antibody, paxillin a antibody, PXN antibody, Pxn antibody, Pax antibody, pxn.S antibody, pxna antibody, LOC696336 antibody, pxn antibody
Background
The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68- kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells.Synonyms: FLJ16691
Gene ID
5829
NCBI Accession
NP_001074324
UniProt
P49023
Pathways
MAPK Signaling , EGFR Signaling Pathway , Response to Growth Hormone Stimulus , Cell-Cell Junction Organization , Maintenance of Protein Location , CXCR4-mediated Signaling Events , Signaling Events mediated by VEGFR1 and VEGFR2 , Signaling of Hepatocyte Growth Factor Receptor , VEGF Signaling
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