SLC17A7 antibody (C-Term)

Catalog No. ABIN1109032

Product Details anti-SLC17A7 Antibody

Target: SLC17A7 (Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 7 (SLC17A7))

Binding Specificity: C-Term

Reactivity: Rat, Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLC17A7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Detects ~52 kDa. No cross-reactivity against VGLUT2.

Purification: Protein G Purified

Clone: S28-9

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, 50 % Glycerol, 0.09 % Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for SLC17A7

Target: SLC17A7 (Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 7 (SLC17A7))

Alternative Name: SLC17A7 / VGLUT1 (SLC17A7 Products)

Synonyms: 2900052E22Rik antibody, AI851913 antibody, VGluT1 antibody, Vglut1 antibody, BNPI antibody, VGLUT1 antibody, slc17a7 antibody, vglut1 antibody, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 antibody, solute carrier family 17 member 7 antibody, solute carrier family 17 (vesicular glutamate transporter), member 7a antibody, Slc17a7 antibody, SLC17A7 antibody, slc17a7a antibody

Background: VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate (1). Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate (2).Synonyms: BNPI, Brain-specific Na(+)-dependent inorganic phosphate cotransporter, Solute carrier family 17 member 7, Vesicular glutamate transporter 1

Gene ID: 116638