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CD14 antibody

CD14 Reactivity: Human, Cynomolgus, Rhesus Monkey, Baboon, Dog FACS, Neut Host: Mouse Monoclonal M5E2 unconjugated
Catalog No. ABIN1177335
  • Target See all CD14 Antibodies
    CD14
    Reactivity
    • 229
    • 46
    • 30
    • 29
    • 28
    • 28
    • 25
    • 24
    • 22
    • 18
    • 15
    • 14
    • 10
    • 9
    • 8
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Cynomolgus, Rhesus Monkey, Baboon, Dog
    Host
    • 187
    • 62
    • 16
    • 3
    • 1
    Mouse
    Clonality
    • 205
    • 64
    Monoclonal
    Conjugate
    • 113
    • 28
    • 21
    • 16
    • 12
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD14 antibody is un-conjugated
    Application
    • 187
    • 97
    • 58
    • 47
    • 43
    • 42
    • 20
    • 19
    • 14
    • 13
    • 13
    • 12
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Neutralization (Neut)
    Brand
    BD Pharmingen™
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    Clone
    M5E2
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CD14 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    Preservative
    Azide free
    Storage
    4 °C
    Storage Comment
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Wright, Ramos, Tobias, Ulevitch, Mathison: "CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein." in: Science (New York, N.Y.), Vol. 249, Issue 4975, pp. 1431-3, (1990) (PubMed).

  • Target
    CD14
    Alternative Name
    CD14 (CD14 Products)
    Synonyms
    CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
    Background
    The M5E2 monoclonal antibody specifically binds to CD14, a 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein expressed at high levels on monocytes. Additionally, the anti-CD14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some Langerhans cells. CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB.
    Synonyms: LPS receptor, LPS-R, Myeloid cell-specific leucine-rich glycoprotein
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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