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CD14 antibody

CD14 Reactivity: Human, Monkey, Dog, Pig, Sheep, Rabbit, Cow, Goat, Cat, Mink FACS, WB, Func, EIA Host: Mouse Monoclonal Tük4 unconjugated
Catalog No. ABIN118508
  • Target See all CD14 Antibodies
    CD14
    Reactivity
    • 225
    • 45
    • 30
    • 29
    • 28
    • 28
    • 25
    • 24
    • 22
    • 18
    • 15
    • 14
    • 10
    • 9
    • 8
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Monkey, Dog, Pig, Sheep, Rabbit, Cow, Goat, Cat, Mink
    Host
    • 186
    • 58
    • 16
    • 3
    • 1
    Mouse
    Clonality
    • 204
    • 60
    Monoclonal
    Conjugate
    • 109
    • 28
    • 21
    • 15
    • 12
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD14 antibody is un-conjugated
    Application
    • 186
    • 93
    • 56
    • 47
    • 43
    • 42
    • 20
    • 15
    • 14
    • 13
    • 13
    • 12
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography on Protein G
    Endotoxin Level
    Low Endotoxin
    Clone
    Tük4
    Isotype
    IgG2a
    Top Product
    Discover our top product CD14 Primary Antibody
  • Application Notes
    Flow Cytometry: 1/100 - 1/200, use 10 μL of suggested working dilution to label 1x10^6 cells or 100 μL whole blood. ELISA. Western Blot: under reducing conditions. Functional Assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
  • Target
    CD14
    Alternative Name
    CD14 (CD14 Products)
    Synonyms
    CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
    Background
    CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein
    Gene ID
    9606
    UniProt
    P08571
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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