Integrin Alpha2b antibody (CD41)

Details for Product anti-CD41 Antibody No. ABIN118658, Supplier: Log in to see
Antigen
  • AI172977
  • CD41
  • CD41B
  • GpIIb
  • alphaIIb
  • BDPLT16
  • BDPLT2
  • GP2B
  • GPIIb
  • GT
  • GTA
  • HPA3
  • integrin alpha 2b
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • Itga2b
  • ITGA2B
Alternatives
anti-Human Integrin Alpha2b antibody for Biochemical Assay
Reactivity
Human
416
149
28
25
20
18
16
11
7
5
2
2
1
1
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1
Host
Mouse
377
115
58
Clonality (Clone)
Monoclonal ()
Conjugate
This Integrin Alpha2b antibody is un-conjugated
64
51
41
15
14
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12
10
10
9
8
7
7
7
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6
5
5
5
5
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3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
422
112
105
92
61
49
48
36
27
15
13
8
7
6
5
3
2
2
2
2
1
1
1
Options
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Immunogen Human platelet plasma membrane. Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Clone PM6-248
Isotype IgG1
Purification Affinity chromatography on Protein G
Alternative Name CD41 / ITGA2B (CD41 Antibody Abstract)
Background CD41 is a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb
Gene ID 9606
UniProt P08514
Pathways Integrin Complex
Application Notes Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0mg/mL
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Michelson, Page, Casey, Trucksess, Love, Milstien, Wilson, Massaquoi, Crofford, Hallett: "An eosinophilia-myalgia syndrome related disorder associated with exposure to L-5-hydroxytryptophan." in: The Journal of rheumatology, Vol. 21, Issue 12, pp. 2261-5, 1995 (PubMed).

Hornby, Brown, Wilkinson, Mattock, Authi: "Activation of human platelets by exposure to a monoclonal antibody, PM6/248, to glycoprotein IIb-IIIa." in: British journal of haematology, Vol. 79, Issue 2, pp. 277-85, 1992 (PubMed).