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CDKN2D antibody (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4))

Details for Product anti-CDKN2D Antibody No. ABIN119188, Supplier: Log in to see
Antigen
  • ink4d
  • p19
  • p19-ink4d
  • CDKN2D
  • ank2
  • INK4D
  • p19-INK4D
  • INK4d
  • p19INK4d
Alternatives
anti-Human CDKN2D antibody for Immunohistochemistry (Frozen Sections)
Reactivity
Human
64
15
14
Host
Mouse
36
28
Clonality (Clone)
Monoclonal ()
Conjugate
This CDKN2D antibody is un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
38
19
18
12
12
11
8
6
4
3
1
1
Supplier
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Immunogen Full length recombinant p19-His tagged
Clone DCS-100-1
Isotype IgG1
Specificity This antibody recognises p19ink4d, a 19 kDa tumour suppressor protein which is a specific inhibitor of cdk4/cdk6. Clone DCS100.1 co-precipitates cdk4/cdk6 in immunoprecipitation studies.
Purification Affinity chromatography on Protein G
Alternative Name CDKN2D / p19INK4d (CDKN2D Antibody Abstract)
Background P19ink4d is periodically expressed during the cell cycle. Maximum induction of p19ink4d occurs as cells enter S phase.Synonyms: Cyclin-dependent kinase 4 inhibitor D, INK4D, p19, p19-INK4d
Gene ID 1032
NCBI Accession NP_001791
UniProt P55273
Pathways Cell Division Cycle
Application Notes Western Blot. Immunoprecipitation. Immunohistochemistry on frozen sections. Recommended Positive Control: Spleen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL IgG
Buffer PBS containing 0.08 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Hirai, Roussel, Kato et al.: "Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6." in: Molecular and cellular biology, Vol. 15, Issue 5, pp. 2672-81, 1995 (PubMed).