GJA1 antibody (Gap Junction Protein, alpha 1, 43kDa) (pSer367)

Details for Product anti-GJA1 Antibody No. ABIN1531807, Supplier: Log in to see
Antigen
  • cx43
  • gjal
  • oddd
  • dfnb38
  • connexin43
  • cx43a1
  • gja1
  • zfCx43.3
  • AU042049
  • AW546267
  • Cnx43
  • Cx43
  • Cx43alpha1
  • Gja-1
  • Npm1
  • AVSD3
  • CX43
  • DFNB38
  • GJAL
  • HLHS1
  • HSS
  • ODDD
  • connexin 43
  • gja1-A
  • Cnx46
  • Cx46
  • Gja-3
  • AI118175
  • Cnx32
  • Cx32
  • Gjb-1
  • gap junction protein, alpha 1, 43kDa
  • connexin 43
  • CONNEXIN 43 protein
  • connexin 43-like
  • gap junction protein, alpha 1
  • gap junction protein, alpha 3
  • gap junction protein, beta 1
  • gja1
  • cx43
  • CX43
  • CONNEXIN 43
  • LOC100359132
  • Gja1
  • GJA1
  • Gja3
  • Gjb1
Alternatives
anti-Cow (Bovine) GJA1 antibody for Immunohistochemistry (Frozen Sections)
Epitope
pSer367
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Reactivity
Human, Mouse (Murine), Rat (Rattus)
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Host
Rabbit
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Clonality
Polyclonal
Conjugate
This GJA1 antibody is un-conjugated
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Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
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Options
Supplier
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Supplier Product No.
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Immunogen The antiserum was produced against synthesized peptide derived from human Connexin 43 around the phosphorylation site of Ser367.
Isotype IgG
Specificity Connexin 43 (Phospho-Ser367) Antibody detects endogenous levels of Connexin 43 only when phosphorylated at Ser367.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation.
Purity > 95 %
Alternative Name Connexin 43 (GJA1 Antibody Abstract)
Background Molecular weight of target protein: 43 kDa
Synonyms: Connexin 43, CX43, CXA1, CXN-43, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein, GJA1
Molecular Weight 43 kDa
Gene ID 2697
OMIM 121014
UniProt P17302
Research Area Extracellular Matrix, Cytoskeleton, Signaling
Pathways MAPK Signaling, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
Application Notes WB: 1:500-1:1000
IHC: 1:50-1:100
ELISA: 1:20000
Optimal working dilution should be determined by the investigator.
Comment

Unigene-Number: Hs.74471 (NCBI Gene Symbol: GJA1)

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 52 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Stable at -20 °C for at least 1 year.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (pSer367) antibody (ABIN1531807) Western blot analysis of extracts from K562 cells treated with PMA 200ng/ml 10', usin...
Immunohistochemistry (IHC) image for anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (pSer367) antibody (ABIN1531807) Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Conn...
Background publications Boengler, Schulz, Heusch: "Connexin 43 signalling and cardioprotection." in: Heart (British Cardiac Society), Vol. 92, Issue 12, pp. 1724-7, 2006 (PubMed).

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