NEFM antibody (C-Term)
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- Target See all NEFM Antibodies
- NEFM (Neurofilament Triplet M Protein (NEFM))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Cow, Rabbit, Dog, Horse, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NEFM antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- EVEGKEEVEQ ETKEKGSGRE EEKGVVTNGL DLSPADEKKG GDKSEEKVVV
- Predicted Reactivity
- Cow: 93%, Dog: 86%, Horse: 86%, Human: 100%, Rabbit: 93%, Rat: 86%, Sheep: 93%
- Characteristics
- This is a rabbit polyclonal antibody against NEFM. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human NEFM
- Top Product
- Discover our top product NEFM Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 540 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NEFM (Neurofilament Triplet M Protein (NEFM))
- Alternative Name
- NEFM (NEFM Products)
- Synonyms
- NEF3 antibody, NF-M antibody, NFM antibody, Nef3 antibody, Nfm antibody, NF160 antibody, NF165 antibody, nef-m antibody, nef3 antibody, nefm antibody, nf-m antibody, zgc:112359 antibody, nefm-a antibody, nefm-b antibody, neurofilament medium antibody, neurofilament triplet M protein antibody, neurofilament, medium polypeptide antibody, neurofilament medium polypeptide antibody, neurofilament medium L homeolog antibody, neurofilament, medium polypeptide a antibody, neurofilament medium S homeolog antibody, NEFM antibody, Nefm antibody, TVAG_582010 antibody, TVAG_379630 antibody, nefm.L antibody, nefma antibody, nefm.S antibody
- Background
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Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: NEF3, NF-M, NFM
Protein Interaction Partner: SART3, PARK2, RB1, SMAD2, FOS, IQCB1, SIRT7, UBC, DISC1, TNIK, SQSTM1, MINK1, STXBP1, NEFH, APOE,
Protein Size: 540 - Molecular Weight
- 59 kDa
- Gene ID
- 4741
- NCBI Accession
- NM_001105541, NP_001099011
- UniProt
- E9PBF7
- Pathways
- Brown Fat Cell Differentiation
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