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TRF2 antibody (AA 324-500)

TERF2 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 3H6B4 unconjugated
Catalog No. ABIN1724941
  • Target See all TRF2 (TERF2) Antibodies
    TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 324-500
    Reactivity
    • 44
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 40
    • 4
    • 2
    Mouse
    Clonality
    • 42
    • 4
    Monoclonal
    Conjugate
    • 23
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRF2 antibody is un-conjugated
    Application
    • 34
    • 21
    • 18
    • 11
    • 10
    • 8
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human TERF2 (AA: 324-500) expressed in E. coli.
    Clone
    3H6B4
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Galati, Magdinier, Colasanti, Bauwens, Pinte, Ricordy, Giraud-Panis, Pusch, Savino, Cacchione, Gilson: "TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner." in: PLoS ONE, Vol. 7, Issue 4, pp. e34386, (2012) (PubMed).

    Diehl, Idowu, Kimmelshue, York, Jackson-Cook, Turner, Holt, Elmore: "Elevated TRF2 in advanced breast cancers with short telomeres." in: Breast cancer research and treatment, Vol. 127, Issue 3, pp. 623-30, (2011) (PubMed).

  • Target
    TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
    Alternative Name
    TERF2 (TERF2 Products)
    Synonyms
    TERF2 antibody, TRBF2 antibody, TRF2 antibody, trf2 antibody, telomeric repeat binding factor 2 antibody, telomeric repeat binding factor 2 L homeolog antibody, TERF2 antibody, Terf2 antibody, terf2.L antibody
    Background

    Description: This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. , , ,

    Aliases: TRF2, TRBF2

    Molecular Weight
    55.6 kDa
    Gene ID
    7014
    HGNC
    7014
    Pathways
    Cell Division Cycle, Telomere Maintenance
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