ADAMTS5 antibody (Internal Region)

Catalog No. ABIN1731535

Product Details anti-ADAMTS5 Antibody

Target: ADAMTS5 (ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAMTS5 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with human ADAMTS5

Cross-Reactivity (Details): BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Antigen affinity purified

Immunogen: Synthetic 16 amino acid peptide from internal region of human ADAMTS5. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Monkey (100%), Marmoset (100%), Rat (94%), Dog (94%), Bat (94%), Bovine (94%)

Isotype: IgG

Application Details

Application Notes:

Working dilution: IHC - P (20 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.

Target Details for ADAMTS5

Target: ADAMTS5 (ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5))

Alternative Name: ADAMTS5 (ADAMTS5 Products)

Synonyms: 9530092O11Rik antibody, ADAM-TS5 antibody, ADAMTS1 antibody, ADAMTS11 antibody, AI481094 antibody, ASMP-2 antibody, ADAM-TS 11 antibody, ADAM-TS 5 antibody, ADAMTS-11 antibody, ADAMTS-5 antibody, ADMP-2 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 5 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 5 antibody, ADAMTS5 antibody, adamts5 antibody, Adamts5 antibody

Background: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.

UniProt: Q9UNA0