PTPRM antibody
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- Target See all PTPRM Antibodies
- PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTPRM antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody detects Protein Tyrosine Phosphatase Mu (Family: Protein Phosphatase, Subfamily: R2A), internal domain of human.
- Purification
- Peptide immunogen affinity column.
- Immunogen
- PTPRM antibody was raised against synthetic peptide from internal domain of human PTPRM. Genename: PTPRM
- Top Product
- Discover our top product PTPRM Primary Antibody
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- Application Notes
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Immunohistochemistry on paraffin embedded sections: 15 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.09 % sodium azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody at 2 - 8 °C up to one month or in aliquots at -70 °C for longer.
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- Target
- PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))
- Alternative Name
- PTPRM (PTPRM Products)
- Synonyms
- cb984 antibody, ptprm antibody, zgc:110218 antibody, PTPRM antibody, p-ptp-mu antibody, ptprl1 antibody, r-ptpu antibody, rptpm antibody, rptpu antibody, PTPRL1 antibody, R-PTP-MU antibody, RPTPM antibody, RPTPU antibody, hR-PTPu antibody, RPTPmu antibody, mKIAA4044 antibody, protein tyrosine phosphatase, receptor type, M, a antibody, protein tyrosine phosphatase, receptor type M antibody, protein tyrosine phosphatase, receptor type, M, b antibody, receptor-type tyrosine-protein phosphatase mu antibody, protein tyrosine phosphatase, receptor type, M antibody, ptprma antibody, PTPRM antibody, ptprmb antibody, ptprm antibody, LOC100550127 antibody, LOC100564083 antibody, Ptprm antibody
- Background
- PTP mu, a R2A receptor protein tyrosine phosphatase, is composed of an extracellular segment containing a MAM domain, an immunoglobulin domain and four fibronectin type III repeats, a transmembrane segment, and two intracellular protein phosphatase domains. PTP mu has been shown to affect cell-cell aggregation, regulate cardiac myocyte Kv1.5 channel expression, and promote neurite outgrowth of retinal ganglion cells. The human PTP mu gene is localized on chromosome 18pter-q11, a region with frequent abnormalities implicated in human cancer. PTP mu may be important in responses to pathological conditions associated with the loss of cell-cell interactions in the heart.Synonyms: PTPRL1, Protein-tyrosine phosphatase mu, R-PTP-mu, RPTPU, Receptor-type tyrosine-protein phosphatase mu
- Gene ID
- 5797
- NCBI Accession
- NP_001098714
- UniProt
- P28827
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