Transforming Growth Factor, beta 1 (TGFB1) (Middle Region) antibody

Details for Product No. ABIN183579
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Antigen
Synonyms
TGF-beta, ai39657, tgfb1, wu:fb13a07, xx:ai39657, TGFB, TGFbeta, TGFB1, TGFBI, csd, cdb1, cdg2, csd1, csd2, csd3, ebmd, lcd1, bigh3, cdgg1, betaig-h3, MGC146225, TGFB4, CED, DPD1, LAP, TGF-BETA-1, Tgf ... show more
TGF-beta, ai39657, tgfb1, wu:fb13a07, xx:ai39657, TGFB, TGFbeta, TGFB1, TGFBI, csd, cdb1, cdg2, csd1, csd2, csd3, ebmd, lcd1, bigh3, cdgg1, betaig-h3, MGC146225, TGFB4, CED, DPD1, LAP, TGF-BETA-1, Tgfb, TGF-beta1, TGFbeta1, Tgfb-1, TGF-beta5, ced, dpd1, lap, tgf-beta, tgfb, tgfb5, tgfbeta, tgf show less
Epitope
Middle Region
(28), (9), (7), (6), (5), (5), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Pig (Porcine), Dog (Canine), Cow (Bovine)
(196), (49), (44), (25), (16), (16), (16), (12), (4), (4), (4), (4), (2), (2), (1), (1), (1)
Host
Rabbit
(170), (74), (4), (3), (2), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(17), (12), (7), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(167), (137), (70), (61), (40), (36), (28), (21), (19), (12), (4), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN183579
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Immunogen Synthetic peptide directed towards the middle region of mouse TGFB1
Sequence DTPEWLSFDV TGVVRQWLNQ GDGIQGFRFS AHCSCDSKDN KLHVEINGIS
Predicted Reactivity Mouse : 100 %, Rat : 90 %, Pig : 90 %, Guinea pig : 80 %, Bovine : 70 %, Dog : 70 %, Horse : 70 %, Sheep : 70 %
Characteristics This is a rabbit polyclonal antibody against TGFB1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TGFB1
Background Tgfb1 is a multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodelling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
Molecular Weight 43 kDa
Gene ID 21803
NCBI Accession NP_035707, NM_011577
UniProt P04202
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 390 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Transforming Growth Factor, beta 1 (TGFB1) (Middle Region) antibody WB Suggested Anti-TGFB1 Antibody Titration: 0.2-1 ug/ml or 1:5000 to 1:1000 dilution.SP2/0 cell lysate
anti-Transforming Growth Factor, beta 1 (TGFB1) (Middle Region) antibody (2) anti-Transforming Growth Factor, beta 1 (TGFB1) (Middle Region) antibody (Image 2)
anti-Transforming Growth Factor, beta 1 (TGFB1) (Middle Region) antibody (3) anti-Transforming Growth Factor, beta 1 (TGFB1) (Middle Region) antibody (Image 3)
anti-Transforming Growth Factor, beta 1 (TGFB1) (Middle Region) antibody (4) rat and mouse
Background publications Cheon, Wei, Gurung et al.: "Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 6, pp. 692-701, 2006 (PubMed).

Validation Images
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