GABRA2 antibody (Middle Region)

Catalog No. ABIN184227

Product Details anti-GABRA2 Antibody

Target: GABRA2 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRA2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PMDAHSCPLK FGSYAYTTSE VTYIWTYNAS DSVQVAPDGS RLNQYDLLGQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GABRA2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GABRA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 451 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GABRA2 antibody (ABIN184227)

Kitayama, Morita, Sultana, Kikushige, Mgita, Ueno, Hirata, Kanematsu: "Phospholipase C-related but catalytically inactive protein modulates pain behavior in a neuropathic pain model in mice." in: Molecular pain, Vol. 9, pp. 23, (2013) (PubMed).

Tian, Chen, Cross, Edenberg: "Alternative splicing and promoter use in the human GABRA2 gene." in: Brain research. Molecular brain research, Vol. 137, Issue 1-2, pp. 174-83, (2005) (PubMed).

Target Details for GABRA2

Target: GABRA2 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2))

Alternative Name: GABRA2 (GABRA2 Products)

Synonyms: C630048P16Rik antibody, Gabra-2 antibody, gamma-aminobutyric acid type A receptor alpha2 subunit antibody, gamma-aminobutyric acid type A receptor alpha1 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 2 antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 2 S homeolog antibody, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 antibody, GABRA2 antibody, GABRA1 antibody, gabra2 antibody, Gabra2 antibody, gabra2.S antibody

Background: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the gaba/benzodiazepine receptor and opening an integral chloride channel.
Protein Interaction Partner: UBQLN1,
Protein Size: 451

Molecular Weight: 51 kDa

Gene ID: 2555

NCBI Accession: NM_000807, NP_000798

UniProt: P47869