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CD14 antibody

CD14 Reactivity: Human FACS, IHC, ELISA Host: Mouse Monoclonal unconjugated
Catalog No. ABIN1843073
  • Target See all CD14 Antibodies
    CD14
    Reactivity
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    Human
    Host
    • 186
    • 58
    • 16
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    Mouse
    Clonality
    • 204
    • 60
    Monoclonal
    Conjugate
    • 109
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    This CD14 antibody is un-conjugated
    Application
    • 186
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CD14 expressed in E. Coli.
    Isotype
    IgG1
    Top Product
    Discover our top product CD14 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • Target
    CD14
    Alternative Name
    CD14 (CD14 Products)
    Synonyms
    CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
    Background
    CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.
    Molecular Weight
    40 kDa
    Gene ID
    929
    UniProt
    P08571
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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